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Recent Submissions

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Exploring the Material Bases for Outmigration and Human Trafficking in the Farming Communities of Kwara State, Nigeria
(African Studies Centre Univesrity of Leiden, 2023) Sheu-Usman Oladipo Akanbi; Mercy Funke Salami; Olanrewaju Solomon
The perception of human trafficking among selected rural-farming households, analysis of data obtained from 120 heads of farming households using descriptive statistics and 5-point Likert-type scale indicate that the probability of exposure to human trafficking is not gender-selective. About 77.5% of the respondents claimed to have out-migrants in their household, more than half (54.2%) of which were in the age range 10-20 years at the time of move. Major reasons for this push include : lack of employment opportunities (mean score=4.6 out of 5), lack of better social services and amenities (mean = 4.5 out of 5) and unequal access to better education (mean=4.4 out of 5) while high wage and income difference in working destination (mean=4.2 out of 5) was a major pull factor. This study found that most of the victims get into agents’ hands as a result of taking decision to search for employment opportunities, better social services and amenities and furtherance of education in intended destination.
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Conflict resolution and management for sustainable peace and security in Nigerian’s educational System.
(Institute of Education, University of Nigeria, Nsukka., 2020-12-15) Olaniyi, A. J.
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Atazanavir/ritonavir increased tizoxanide exposure from oral nitazoxanide through pharmacokinetic interaction in healthy volunteers
(2024-02-22) Abdulafeez Akinloye; Timothy Oyedeji; Oluwasegun Eniayewu; Babatunde Adeagbo; Oluseye Bolaji; Steve Rannard; Andrew Owen; Adeniyi Olagunju
Nitazoxanide use is limited by gastrointestinal side effects associated with increasing dose. In this drug repurposing study, we investigated the possibility of enhancing the exposure of its active metabolite, tizoxanide, through pharmacokinetic interaction with atazanavir/ritonavir. In this crossover drug-drug interaction study, 18 healthy participants received a single dose of 1000mg of nitazoxanide alone and in combination with 300/100mg atazanavir/ritonavir in period 1 and 2 re-spectively. On both days, blood samples for intensive pharmacokinetic analyses were collected at 0–12 hours post-dose. To explore the utility of dried blood spots (DBS) as alternative to plasma for tizoxanide quantification, 50µL of blood from some participants was spotted on DBS cards and correlated with plasma concentrations. Pharmacokinetic parameters were derived by non-compartmental analysis and compared between both periods. Co-administration of nita-zoxanide with atazanavir/ritonavir resulted in a significant increase in tizoxanide plasma exposure [GMR (90% CI) of AUC0-12h, Cmax and C12h being 1.872 (1.870–1.875), 2.029 (1.99–2.07) and 3.14 (2.268–4.352) respectively]. DBS concentration (%CV) was 46.3% (5.6%) lower than plasma con-centrations, and strong correlation (R = 0.95, P<0.001) between DBS-derived plasma concentration and plasma concentrations. Co-administration with atazanavir/ritonavir enhanced tizoxanide ex-posure with no report of adverse events in healthy volunteers.
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Quality teacher education for social reconstruction in Nigeria.
(Department of Health Promotion and Environmental Health Education, University of Ilorin, Ilorin, Nigeria,, 2017-12-20) Lawal, R.T., Olaniyi, A. J. & Abolade S. B.
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Historical Interpretation of Eternal Security in the Evangelical Church Winning All (ECWA) in Nigeria
(Joes Publications (learnwithjoes), 2023) Mary Taiye Daniel
ONE OF THE MAJOR doctrines in Christianity is the doctrine of salvation, which finds its deepest meaning in the spiritual aspect of life. Its fulfillment is held vigorously in the death and resurrection of Jesus Christ which brought about salvation which is the highest goal of Christianity. In the 'Articles of faith and practice' of different churches, teachings on salvation vary in content but not in goal. This variation became unavoidable from the point of view of God's sovereignty and omnipotency. This variation was further compounded by the unanimity in the doctrines of churches that God is holy and has zero tolerance for sin in His sovereignty. Within this context, these schools of thought emerged namely: Calvinism and Armenianism. In Calvinism, God offered irresistible grace to those whom He elected to save in the exercise of His sovereign power, while in Armenianism God's grace was the source of redemption but could be resisted by people through free choice. The doctrine of ECWA as their articles of faith and practice (8) confirmed Calvinism. The objectives of the paper were to determine the import of sin and how the doctrine of eternal security could remain intact where sin did not abound; to determine the significance of dependence on God and how the conditions can be fulfilled as requirement for ' eternal security. The research methods used were historical and interpretative. Some major findings were as follows; though some Christian denominations do not profess the doctrine of eternal security, but there is a reflection of the doctrine in some, and once God's exercise of sovereignty was not denied this attribute would as well blend with God's grace not to sin; sin and the practice of it could be said to be voluntary and those who chose God would not see the beauty of sin over belief in God; the imminence of eternal salvation was a design of God and He remained its guarantor and; the Calvinism and Arminians need God's grace as strong bottom-line for the achievement of eternity. The Calvinist argument dovetails into the acceptance of the view that God remained the author of Christian conversion. (Acts 11;18). The element of faith accompanied with repentance is the acknowledgment of the truth of the gospel. Apparently, the stable life in Christ is taken to be vulnerable to regeneration and transformation; thereby guaranteeing eternal security. It is recommended that Christians should be diligent, hopeful and upright for the attainment of eternal security.