Browsing by Author "Lawal, Amudat"

Now showing 1 - 4 of 4
  • Item
    Characterisation and treatment of spent deposited sludge of transformer oil (DSTO) by acid leaching and solvent extraction
    (Published by Taylor & Francis on behalf of the Institute and The AusIMM, 2017-08-31) Baba, Alafara A.; Ayodele, Joshua S.; Ameen, Oloduowo M.; Jimoh, Abdulrasaq; Johnson, Uduakobong; Jimoh, Bilikisu A.; Lawal, Amudat
    The characterisation of spent transformer oil to determine its fitness for re-refining as well as the recovery of metals by hydrometallurgical treatment in chloride medium has been investigated. The leaching experiments on the spent material showed that its dissolution increases with leachant concentration performed at 75°C. Leaching studies showed that at optimal conditions, the dissolution reached 93% by 1.0 mol L−1 HCl solution within 120 min at 75°C. The solvent extraction of copper by bis(2,2,4-trimethylpentyl) phosphinic acid (CYANEX®272) in kerosene from a pregnant solution of aqueous spent deposited sludge of transformer oil containing 1243.4 mg L−1 Cu++, 389.2 mg L−1 Fe++/+++, 110.7 mg L−1 Ca++ and 235 mg L−1 Al+++ was studied. The results for the solvent extraction give an extraction efficiency of 91.77% total copper acquired via 0.2 mol L−1 CYANEX®272 in kerosene at 27 ± 2°C within 25 min at pH 4.0. A 0.1 mol L−1 HCl solution was found to be sufficient for the stripping of about 94.77% copper from the loaded organic phase. The Fourier transform–infrared spectroscopic analysis of the loaded organic phase supports the stripping experiment as there was no Cu metal ion present in the separated organic phase.
  • Item
    Chelation, Characterization and Antimicrobial Screening of Some Mixed Antituberculosis–Vitamin Metal Drug Complexes
    (Al-Hikmah University, 2017-05-04) Bamigboye, Mercy O; Obaleye, Joshua A; Lawal, Amudat; Babamale, Halimah Funmilayo; Ajibola, A. A; Adimula, Vincent O; Lawal, Mistura
    In this study, mixed Zn(II), Cu(II), Co(II) complexes of Isoniazid and vitamin C were synthesized and characterized by melting point, conductivity measurement, Fourier Transform Infra-red (FT-IR), Atomic Absorption Spectroscopy and elemental analyses. The bonding nature of the mixed parent ligands and the structure of the complexes were based on analytical and spectroscopic techniques. The complexes were proposed to have the formula [M1L1L2(Cl2)], [M2L1L2(SO4)], [M3L1L2(Cl2)] where M1 = Zn(II), M2 = Cu(II), M3= Co (II) L1= Isoniazid and L2 = Vitamin C. The infra-red data relate to the results of the most informative and indicative region. The result of spectra data confirmed that the two ligands were bidentate in their mode of coordination with the metal ions. The complexes are in octahedral geometry and the molar conductance was found to be non-electrolytic in nature. Antimicrobial test was carried out against four bacterial species namely Bacillus subtilus, Staphylococuss aureus, Escherichia coli and Pseudomonas aeroginosa. All the complexes showed higher antibacterial activity at the same concentration against the microorganisms used compared to the ligands.
  • Item
    Mixed metal complexes of Artemether, Lumefantrine and Ascorbic acid: Synthesis, characterization and biological activity studies
    (Library and Publications Committee, University of Ilorin, Ilorin, Nigeria., 2019) Babamale, Halimah Funmilayo; Rajee, Abdullahi Ola; Obaleye, Joshua Ayoola; Lawal, Amudat; Bamigboye, Mercy Obaleye; Lawal, Misitura; Sa'ad, H.O.
    Some transition metal complexes of mixed artemether, ascorbic acid and lumefantrine have been synthesized and characterized using UV/Vis, FTIR, Atomic Absorption Spectroscopy (AAS) and Gas chromatography-Mass Spectroscopy (GC-MS). The results revealed that the artemether and ascorbic acid are chelating ligands and coordinates through the oxygen of the carbonyl groups while lumefantrine coordinates through the hydroxyl group in a monodentate fashion. The metal complexes were investigated for biological activity using five bacterial species - Staphylococcus aureus, Escherichia coli, Bacillus aureus and Pseudomonas aeruginosa. It was observed that the synthesized complexes were more effective towards the five bacteria species than the free drugs.
  • Item
    Synthesis, Characterization and Antimicrobial Activity of Amodiaquine and Sulphadoxine Mixed Ligand-metal Complexes
    (The Nigerian Society of Biochemistry and Molecular biology., 2014) Obaleye, Joshua Ayoola; Lawal, Amudat; Rajee, Abdullahi Ola; Shittu, Fatimah B.
    Four mixed ligand metal complexes [Co(AMD)(SUF)Cl2],[Cu(AMD)(SUF)Cl2], [Ni(AMD)(SUF)Cl2] and [Zn(AMD)(SUF)Cl2] of Amodiaquine and Sulphadoxine were synthesized. The complexes formed were characterized by solubility and melting point determination, conductivity measurements,, infrared, ultraviolet and NMR spectroscopy and elemental analysis. The analytical and spectroscopic data revealed the formation of new complexes. The ligands used were found to acts as monodentates. Sulphadoxine, coordination occurs through the N atom of the NH, group in the complexes while for amodiaquine, coordination occurs also through the nitrogen of the quinoline group. Hence, tetrahedral geometry was assigned for all the synthesized complexes, since they also coordinate with the chloride ions. Investigation of the antibacterial study was also carried out which indicated that the synthesized complexes exhibits some inhibitory activities higher than their parent ligands most especially for the Co(II) and Cu(I) complexes.