Browsing by Author "Issa, A"
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Item Reference values for the six-minute walk test in Nigerian adolescents aged 10 to 18 years(College of Health Sciences, Osun State University, 2019) Abdulkadir, Mohammed Baba; Ibraheem, Rasheedat Mobolaji; Akintade, O.O; Suberu, H.D.; Issa, A; Alabi, K.OObjective: To determine baseline six-minute walk distance in Nigerian adolescents and establish its relationship with age, gender and anthropometric parameters. Methods: One hundred and eighty healthy adolescents (10 – 18 years) were recruited from three schools. Six-minute walk test was conducted as described by the American Thoracic Society. Demographic and anthropometric characteristics were related to achieve six-minute walk distance. Amathematical formula for predicting six-minute walk distance was generated. Results: The mean ± SD six-minute walk distance was 590.1 ± 72.02 m and was significantly longer in males (p= 0.001) among adolescents aged 10- 16 years. Age was the only characteristic significantly associated with six-minute walk distance following multiple linear regression analyses. The formulae, [six-minute walk distance = 317.3 + 21.5 x age (years) in males and 117 + 33.0 x age (years) in females] closely approximated to measured six-minute walk distance. Conclusion: This study has derived reference values for 6-minute walk test in adolescents; the use of these reference values should consider age and gender variations.Item Relationship Between Teachers’ Competence and Pupils’ Attitude to Learning of Basic Science and Technology in Kwara Central.(A publication of the Department of Counselling and Human Development Studies, University of Ibadan, Nigeria., 2024-03-06) Adedigba, O.; Issa, A; Ahmed, T. A.The role of teachers in shaping students' attitudes towards learning is crucial in achieving educational goals. Competent teachers can effectively engage and motivate their pupils, particularly in subjects such as Basic Science and Technology. The study investigated teachers’ competence as a determinant of pupils’ attitude to learning of Basic Science and Technology in Kwara Central. The study adopted a descriptive research design of correlation type. The population for this study comprised all 12,134 primary school teachers in Kwara State while the target population included all 5,393 teachers in Kwara Central. A sample size of 341 was selected using a proportional and simple random sampling technique. Teachers’ Competence Rating Scale (TCRS) with r=0.86 and Pupils' Attitude to Learning of Basic Science and Technology Rating Scale (PALBSTRS) with 0.82 were the two instruments used for data gathering. The study was guided by two research questions and one hypothesis. Data gathered were analyzed using frequency, mean and percentage and Pearson Product Moment Correlation (PPMC). The findings showed relationship between teachers’ competence and pupils’ attitude to learning of Basic Science and Technology. It was recommended that government and private school owners should provide professional development opportunities for teachers to improve their competence in teaching Basic Science and Technology. This may motivate pupils to have right attitude towards learning basic science and technology.Item Relationships between cardiovascular signs and neurological signs in asphyxiated neonates in Ilorin, North Central Nigeria(Makarere University Medical School, Kampala, Uganda, 2021) Issa, A; Abdulkadir, Mohammed Baba; Adesiyun, OO; Owolabi, B; SUberu, H; Alabi, K.O; Bakare, R.R.Background: Perinatal asphyxia is a condition associated with multiple organ dysfunctions inclusive of cardiovascular dys function. Neurologic predictors of survival have been studied, but little has been reported regarding cardiovascular signs and their role in determining outcome in asphyxia. Objective: The study aimed to determine the relationship between cardiovascular signs and outcomes in asphyxiated new borns with hypoxic ischaemic encephalopathy. Methods: This was a cross sectional study involving asphyxiated new-born babies recruited within the first 24 hours of life. Hypoxic ischaemic encephalopathy staging was done using Sarnat and Sarnat staging. All patients had a detailed cardi ovascular examination on admission, after initial resuscitation (30 – 60 minutes) into admission, and were followed till final outcome: discharge or death. Results: Eighty-five asphyxiated new-borns with HIE were studied over seven months. Abnormal cardiovascular-related signs identified in the patients included respiratory distress (64.7%), small volume pulse (57.6%), hypotension (52.9%), hy poxemia (48.2%) and shock (32.9%). Five babies died. None of the clinical signs had a significant relationship with mortality. Conclusion: Abnormal cardiovascular signs increased with the progression of HIE staging but had no relationship with mortality.Item Relationships between troponin I and hypoxic–ischemic encephalopathy among newborn babies(Saudi Neonatology Society, 2021) Issa, A; Abdulkadir, Mohammed Baba; Ibraheem, Rasheedat Mobolaji; Ibrahim, O.R; Bello, S.O; Suberu, H.D.; Sanusi, IBackground: A proper evaluation of cardiovascular status, with a view to ensuring early diagnosis of cardiac dysfunction and prompt intervention where necessary, is a recognized approach in the management of asphyxiated neonates. Hence, we determined the levels of a cardiac biomarker (troponin I), its relationship with disease severity, and mortality in asphyxiated neonates with hypoxic–ischemic encephalopathy (HIE). Methods: This was a descriptive study that involved 85 asphyxiated, term appropriate‑for‑gestational age newborn babies with HIE (subjects) and 85 healthy controls within the first 72 h of life. Asphyxiated neonates were classified into HIE stages using Sarnat and Sarnat staging. Blood samples were collected between 24 and 72 h of life to determine the level of troponin I using enzyme‑linked immunosorbent assay. The asphyxiated babies were followed up till discharge or death. Results: The median interquartile range level of troponin I in the subjects was higher compared with the controls, 1.26 (0.97–3.16) ng/ml versus 0.79 (0.79–1.42) ng/ml, P < 0. 001. The levels of troponin I in HIE I, HIE II, and HIE III were 1.26 (1.00–2.37) ng/ml, 1.11 (0.86– 2.96) ng/ml, and 3.58 (1.34–5.58) ng/ml, respectively. Nonsurvivors had a higher cardiac troponin I (4.00 [2.30–6.34] ng/ml) compared with survivors (1.21 [0.95– 2.37] ng/ml), P = 0.015. Conclusion: Cardiac troponin I was significantly higher in asphyxiated subjects compared with healthy controls. Elevated troponin I was associated with higher mortality. Troponin I levels in the first 72 h can help as a prognostic indicator of HIE in term babiesItem Serum brain natriuretic peptide in healthy Nigerian newborn babies(Paediatric Association of Nigeria, 2021) Issa, A; Abdulkadir, Mohammed Baba; Adesiyun, O.O.; Owolabi, B; Bello, S.O.; Bakare, R.R.Background: Brain natriuretic peptide (BNP) is a sensitive biomarker that is valuable in the management of childhood heart failure. Studies have reported racial differences in the level of BNP, especially in the adult population. The level of BNP in healthy Nigerian newborn babies is unknown. Hence, we determined the level of BNP in healthy term appropriate for gestational age (AGA) newborn babies. Methods: This was a cross- sectional study,85 healthy term AGA newborn babies aged 24 to 72 hours. The babies had relevant demographic parameters docu mented in a proforma and BNP assay analysed using ELISA method. Results: The median IQR serum BNP level was 341.43 (313.39 to 425.45) pg/ml. The median level in females, was higher than males, {393.86 (296.97- 460.62) pg/ml vs328.05 (313.61-389.39) pg/ml, p >0.05}.There was no significant relationship between serum BNP and birth weight, chronological age, gestational age, or mode of delivery (p>0.05 in each case). Conclusion: The study demonstrated high BNP levels in healthy term Nigerian newborns. There was no relationship between BNP, the chronological age, birth weight, gender, gestational age or mode of delivery in babies between 24 to 72 hours of life