Browsing by Author "Ameen, Hafsat Abolore"

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    A framework for stakeholder engagement in the adoption of new anti-malarial treatments in Africa:
    (Malaria Journal, 2023) Mokuolu, Olugbenga Ayodeji; Bolarinwa,Oladimeji Akeem; Opadiran, Oluwatumobi Racheal; Ameen, Hafsat Abolore; Dhorda, Mehul; Cheah, Phaik Yeong; Amaratunga,Chanaki; de Haan, Freek; Tindana,Paulina; Dondorp,Arjen M.
    Background Recent reports of artemisinin partial resistance from Rwanda and Uganda are worrisome and suggest a future policy change to adopt new anti-malarials. This is a case study on the evolution, adoption, and implementation of new anti-malarial treatment policies in Nigeria. The main objective is to provide perspectives to enhance the future uptake of new anti-malarials, with an emphasis on stakeholder engagement strategies. Methods This case study is based on an analysis of policy documents and stakeholders’ perspectives drawn from an empirical study conducted in Nigeria, 2019–2020. A mixed methods approach was adopted, including historical accounts, review of programme and policy documents, and 33 qualitative in-depth interviews and 6 focus group discussions. Results Based on policy documents reviewed, the adoption of artemisinin-based combination therapy (ACT) in Nigeria was swift due to political will, funding and support from global developmental partners. However, the implementation of ACT was met with resistance from suppliers, distributors, prescribers, and end-users, attributed to market dynamics, costs and inadequate stakeholder engagement. Deployment of ACT in Nigeria witnessed increased developmental partner support, robust data generation, ACT case-management strengthening and evidence on anti malarial use in severe malaria and antenatal care management. A framework for efective stakeholder engagement for the future adoption of new anti-malarial treatment strategies was proposed. The framework covers the pathway from generating evidence on drug efcacy, safety and uptake; to making treatment accessible and afordable to end-users. It addresses which stakeholders to engage with and the content of engagement strategies with key stakeholders at diferent levels of the transition process. Conclusion Early and staged engagement of stakeholders from global bodies to community level end-users is critical to the successful adoption and uptake of new anti-malarial treatment policies. A framework for these engage ments was proposed as a contribution to enhancing the uptake of future anti-malarial strategies.
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    Assessment of Willingness and Attitude of Female Undergraduates of Universities in Kwara State, Nigeria towards Egg Donation to Infertile Couples
    (2022-07) Ameen, Hafsat Abolore; Ibraheem, Rasheedat M; Oladiji, F; Abdulraheem, HA; Salaudeen, AG; Musa, OI; Aderibigbe, SA; Akande, TM; Abdulraheen, IS; Abdulsalam, TS
    Background: Literature is limited on research focusing on attitudes and willingness of undergraduate females, who are the target population for egg donation clinics. This study investigated the attitude of female undergraduates in Kwara State, north-central Nigeria, towards ethical issues in egg donation and their willingness to donate egg to infertile couples. Methods: We used a descriptive cross-sectional study design. A multistage sampling technique was also used to select 559 female undergraduates in universities in Kwara State enrolled for the 2017/2018 academic session. An adapted questionnaire validated and tested for reliability (r = 0.86) was used for data collection. IBM SPSS version 20 was used to analyse the data. Percentage was used to answer research questions, while Chi-square was employed to test the hypotheses at 0.05 level of significance. The Results: Majority of the respondents were 15-20 years old 371 (66.3%), unmarried 541 (96.8%), Muslims 338 (60.5%), Yoruba (82.8%) and first-year students 304 (54.4%). Only a few respondents 100 (17.8%) believed it is good to support egg donation. Majority 357 (63.9%) believed that egg donors should be compensated (in cash or kind). Only 187 (33.4%) respondents agreed that egg donor and egg recipient should know each other. In addition, majority 503 (89.9%) of the respondents said they would not disclose their involvement in egg donation to their spouses. Slightly more than half (54.9%) of the respondents are not willing to donate their eggs for fear of the procedure, religious and cultural reasons. Conclusion: Female undergraduates in the study area are not in support of egg donation and are mostly unwilling to donate their eggs. The university authorities should include egg donation as a topic in General Studies (GNS) to keep female students abreast of issues in egg donation to enable them make informed decisions prior to donation.
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    Burden and outcome of respiratory morbidities among children and adolescents with sickle cell disease—A retrospective review of emergency presentations in some Nigerian tertiary institutions.
    (Public Library of Science, United States of America, 2024-05-16) Ibraheem, Rasheedat Mobolaji; Abdulkadir, Mohanned Baba; Aliu, Rasaki; Issa, Amudalat; Ibrahim Olayinka Rasheed; Bello, Abdulafeez Oyesola; Abubakar, Fatima Ishaq; Oloyede, Precious Iso; Olasinde, Yetunde Toyin; Briggs, Datonye Christopher; Bashir, MuhammedFaruk; Salau, Qassim Olakunle; Garba, Bilkisu Ilah; Ameen, Hafsat Abolore; Suleiman, Mohammed Bello; Bewaji, Temitayo Olubunmi; Shina, Hassan Kamiludeen
    Background Despite the huge burden of sickle cell disease (SCD) among Nigerian children, the burden and outcome of respiratory illnesses remain undocumented. Thus, we aimed to describe the spectrum and outcome of respiratory illnesses among SCD childrenand adolescentadmissions in ten Nigerian tertiary hospitals. Method A retrospective review of the SCD admission records of children and adolescents with a confirmed diagnosis of respiratory illnesses from 2012 to 2021 in ten tertiary health facilities across five geopolitical zones in Nigeria was conducted. The data, collectedbetween March and June 2023, included the age, sex, diagnosis, complications, duration and outcome of hospitalization. Results Of the 72,333 paediatric admissions, 7,256 (10.0%) had SCD; the proportion of SCD from the total admission ranged from 2.1 to 16.3% in the facilities. Of the 7,256 children and adolescents with SCD, 1,213 (16.7%) had respiratory morbidities. Lower respiratory disease was the most common (70.0%) respiratory entity and the majority were pneumonia (40.1.0%), followed by acute chest syndrome (26.7%). Seventeen (1.4%) patients died; all had lower respiratory diseases [(acute chest syndrome ACS (11, 64.7%), pneumonia; 5, 29.4%, and asthma (1, 5.9%). Based on the proportion of deaths among overall SCD, the 17 death cases contributed 9.4% (95% CI 5.9 to 14.5). Factors associated with deaths included duration of hospitalization less than 72 hours and lower respiratory tract diseases. Conclusion Sickle cell disease is a major contributor to hospitalization among Nigerian children and adolescents, with high respiratory morbidity and mortality. Pneumonia and acute chest syndrome were associated with mortality, andthe highest risk of death within the first 72 hours.
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    Domestic Resource Mobilisation for Sustainable Healthcare Financing in Nigeria
    (Nigerian Postgraduate Medical Journal, 2024-12-04) Bello,Amina Idris; Jimoh,Maryam Abimbola; Tijani, Abdul‑Rasheed Olalekan; Ameen, Hafsat Abolore
    Domestic resource mobilisation (DRM) is vital for achieving sustainable healthcare financing in Nigeria, where dependence on external funding and oil revenues has long hindered health sector progress. The Nigerian healthcare system faces persistent challenges, including inadequate funding, inefficiencies and limited access to essential services, particularly in rural areas. This paper explores the challenges and prospects of DRM as a means of financing healthcare in Nigeria. A Medline search and a search of other internet search engines were carried out for published studies on healthcare financing in Nigeria, Africa and worldwide, we also examined policy documents and healthcare financing data to analyse the potential of DRM in Nigeria. A total of 38 publications were reviewed revealing that mechanisms such as general tax revenue, social insurance systems and community‑based health insurance are central to DRM efforts. However, challenges such as inadequate budgetary allocations, corruption, poor database management and the emigration of health workers persist. Despite these obstacles, there are promising prospects, including increased tax revenue, development of the domestic capital market and the potential for sustainable and equitable healthcare financing through public–private partnerships. To harness these opportunities, the Nigerian government must implement effective policies, strengthen governance structures and promote transparency and accountability. DRM offers a promising path towards reducing dependency on external aid and achieving a more resilient and equitable healthcare system in Nigeria.
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    Evaluation of the awareness and experiences of the primary and secondary school teachers on asthma:
    (Journal of the Pan African Thoracic Society, 2022-10-04) Ibraheem,Rasheedat Mobolaji; Hamzah , Abdul-Lateef Olanrewaju; Ameen, Hafsat Abolore; Katibi,Oludolapo Sherifat; Johnson,Abdul-Wahab Rotimi
    Objectives: Children spend the daytime participating in classes and sports. Hence, as the general caregiver of children during school hours, the teacher has a role in managing those with asthma. The present study aims to identify teachers’ knowledge, attitude, and experiences about childhood asthma in primary and secondary schools in Ilorin, Nigeria. Materials and Methods: A cross-sectional study was conducted among 1532 teachers from 64 schools (24 primary and 40 secondaries) selected through multistage sampling. A 40-item Asthma Knowledge Questionnaire was used to assess teachers’ knowledge about childhood asthma. A  score of <22 out of 40 was considered suboptimal knowledge of childhood asthma. Results: The response rate was 92.8%. Two-thirds of respondents were female. The overall mean age was 33.8 ± 8.1 years. The median (interquartile range [IQR]) teaching duration was 6 (3–11) years. The teachers had the highest median score (60.0%) in the triggers domain and the lowest median score (33.3%) in the symptoms domain. The overall median (IQR) knowledge score of the primary school teachers was 50.0 (30.0–65.0%), and for the secondary school teachers was 52.5 (30.0–65.0%), P = 0.689. Two hundred and ninety-one (55.1%) primary teachers and 479 (53.6%) secondary teachers had suboptimal knowledge. Teachers with an asthmatic relative, an asthmatic child in the class, or who previously witnessed a child with an asthmatic attack had – significantly better asthma knowledge, with each P < 0.05. Conclusion: About half of the teachers surveyed had suboptimal knowledge of asthma. Strategies to improve teachers’ knowledge are crucial for improved childhood asthma management in Ilorin schools.
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    Knowledge and Acceptance of Covid-19 Vaccine Among Adult Residents of a Rural Community in Kwara State, Nigeria
    (2022-07-19) Ameen, Hafsat Abolore; Adana, NS; Aibinuomo, OR; Ibraheem, Rasheedat M; Oladiji, F; Alatishe-Muhammed, BW; Tijani, RO; Adeyemi, OM; Bolarinwa, OA; Uthman, MMB; Abdulraheem, IS; Ahmed, KA
    Background: The rapid production and approval for the use of the Covid-19 vaccine has attracted a lot of skepticism leading to hesitancy in taking the vaccine among many people globally, and in sub-Saharan Africa in particular. Objective: This study aimed at determining the reasons behind the non-acceptance or outright refusal of the Covid-19 vaccine by the people of Ogbondoroko, a rural community in Kwara State, Nigeria. Methods: Descriptive cross-sectional study design was employed and 568 respondents were selected using multistage sampling. IBM Statistical Package for Social Sciences was used for data analysis. Test of association was done using Chi-square at a significance level of P< 0.05 at a 95% confidence. Results: The mean age of the respondents was 48 ± 18.29 years and there was a female preponderance of 408 (71.9%). Majority of the respondents were married (82%); are mostly artisans and earn less than 50 US dollars per month. About half (49.0 %) of the respondents have no formal education. Most of the respondents 544 (95.8%) heard about the Covid-19 vaccine over the radio/television 260 (47.8%) and from health workers 233 (42.8%). Most of the respondents 481 (88.4%) were willing to receive the vaccine. Factors such as age, marital status, employment status, and income of the respondents were significantly associated with awareness of Covid-19 vaccine among them (p≤ 0.05). Conclusion: There was a high level of awareness and acceptance of Covid-19 vaccine amongst rural dwellers in the study area. The use of audience-targeted mass media should be upheld in the dissemination of health messages in the study area in order to continue to achieve the desired results.
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    Knowledge and Pre-marital Haemoglobin Genotype Screening Practices of Religious Leaders in Ilorin Metropolis, North central Nigeria
    (2022-05-15) Ameen, Hafsat Abolore; Aibinuomo, OR; Abdulsalam, ST; Ibraheem, Rasheedat M; Alatishe-Muhammed, BW; Oladiji, F
    Nigeria has a high prevalence of Sickle Cell Disease (SCD) which results in significant morbidity and mortality. Premarital genetic screening for Sickle Cell Trait (SCT) is a cost-effective means of curbing the menace. This study determined the knowledge and practices of religious leaders in the Ilorin metropolis towards pre-marital genotype determination. A descriptive cross-sectional study design and multistage sampling technique were used to select 271 respondents. IBM Statistical Package for Social Sciences (SPSS) version 23 was used for data analysis. Results were presented in prose, tables, and frequency counts while the test of association between variables was done using Chi-square and Fischer's Exact test at a significance level of < 0.05 and confidence level of 95%. Less than half 93 (39.4%) of the respondents knew both parents contribute to a child acquiring SCD while up to 109 (40.2%) strongly agreed that SCD is serious and should be a hindrance to marriage. More than half of 160 (59.0%) respondents recommend pre-marital genotype counseling for intending couples and 156 (57.6%) had recommended pre-marital genotype screening for couples. Up to 165 (60.7%) of the respondents with a tertiary level of education practiced premarital screening of their congregants (p=0.004) and 127 (58.3%) of respondents with good knowledge of SCD also practiced pre-marital screening (p=0.001). Religious leaders in the study area have a considerably high level of knowledge of pre-marital genotype screening and demonstrated a moderate level of practice. Religious leaders in the study area could serve as advocates in awareness creation and community mobilization for pre-marital haemoglobin genotype screening.
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    Knowledge of Oocyte Donation procedure and Health Consequences: a Cross-Sectional Survey of Female Undergraduates in North-Central Nigeria.
    (2022-05) Ameen, Hafsat Abolore; Olaitan, OL; Arimiyau, S; Musa, OA; Ibraheem, Rasheedat M; Abdulrahim, HA; Aderibigbe, SA
    Egg donation is a form of assisted reproductive technology used to help women with infertility. Though egg donation might attract some material benefit, potential egg donors often do not have knowledge of the associated health risks. This study investigated the knowledge of female undergraduates in Kwara State, north-central Nigeria, about oocyte donation to infertile couples. It was a descriptive cross-sectional study carried out in 2018 involving 559 female undergraduates recruited through a multi-stage sampling technique. An adapted questionnaire validated and tested for reliability was used for data collection. Data were analyzed using IBM SPSS version 25 software. Descriptive statistics of frequency count and percentages were used to answer research questions and Chi-square was employed to test the hypotheses at a <0.05 level of significance. Majority of the respondents were 15-20 years old (66.3%, 371) unmarried (96.8%, 541), Muslims (60.5%, 338), Yoruba (82.8%, 463), first-year students (54.4%, 304). Most of the respondents had poor knowledge of oocyte donation (60.3%, 337); poor knowledge of oocyte donation procedure (69.9%, 391), and poor knowledge of the health risks associated with oocyte donation (65.5%, 366). The study revealed that female undergraduates in the study area have poor knowledge of oocyte donation, its procedure, and the attendant health consequences. Universities in the study area should include oocyte donation as a topic in General Studies (GNS) in order to equip students with adequate information on the potential benefits and drawbacks of oocyte donation.
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    Pattern and Predictive Factors of Health‑related Quality of Life of Patients with Hypertension, Diabetes and Concomitant Hypertension with Diabetes in Ilorin, Nigeria
    (Nigerian Postgraduate Medical Journal, 2016) Bolarinwa,Oladimeji Akeem; Ameen, Hafsat Abolore; Sanya, Emmanuel Olatunde; Kolo,Philip Manma; Durowade,Kabir Adekunle; Uthman,Mohammed-Mubashir Babatunde; Ogunmodede,James Ayodele; Biliaminu,Sikiru Ayobami; Odeigah , Loius Okeibunor; Akande,Tanimola Makanjuola
    Background: Hypertension and diabetes are the two most important modifiable risk factors for cardiovascular disease (CVD) among Nigerian population. Because of the lifelong nature of the two diseases and the attendant long treatment regimen required, assessing the health‑related quality of life (HRQoL) is an important outcome of these diseases. Objective: This study assessed the pattern and predictive factors of HRQoL among patients with hypertension, diabetes and concomitant hypertension and diabetes using the 36‑item short‑form version 2. Patients and Methods: A cross‑sectional study of 1203 patients attending the outpatient clinics of the University of Ilorin Teaching Hospital, Ilorin; the patients were sampled using systematic random sampling methods. Patients were divided into those with hypertension, diabetes and both diseases. The predictors of physical and mental component summaries of HRQoL were analysed using Norm‑based Scoring. The level of significance was set at P < 0.05 and 95% confidence interval. Results: The patients with both diseases have lowest physical HRQoL (45.6), while the diabetic patients have the worst mental HRQoL (39.5). Negative predictors of physical HRQoL across the three groups were: drug regimen (hypertension P < 0.001, diabetes P < 0.001, both P = 0.005), CVD complication (hypertension P < 0.001, diabetes P = 0.025) and accompanying persons (P < 0.001). The positive predictors of physical HRQoL across the three groups were medication adherence (hypertension P < 0.001, diabetes P < 0.001 and both P = 0.002). Similarly, medication adherence was the positive predictor for mental HRQoL across the three groups of patients (hypertension P < 0.001, diabetes P = 0.001 and both P < 0.001). Conclusion: This study provided evidence to show that HRQoL across the three categories of patients in Ilorin, Nigeria, is suboptimal. Drug regimen, medication adherence and support from accompanying persons were important predictive factors of HRQoL.
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    Pattern and Predictive Factors of Health‑related Quality of Life of Patients with Hypertension, Diabetes and Concomitant Hypertension with Diabetes in Ilorin, Nigeria
    (Nigerian Postgraduate Medical Journal - Wolters Kluwer: Medknow, 2016) Bolarinwa, Oladimeji Akeem; Ameen, Hafsat Abolore; Sanya, Emmanuel Olatunde; Kolo, Philip Manma; Durowade, Kabir Adekunle; Uthman, Mohammed-Mubashir Babatunde; Ogunmodede, James Ayodele; Biliaminu, Sikiru Ayobami; Odeigah, Loius Okeibunor; Akande, Tanimola Makanjuola
    Background: Hypertension and diabetes are the two most important modifiable risk factors for cardiovascular disease (CVD) among Nigerian population. Because of the lifelong nature of the two diseases and the attendant long treatment regimen required, assessing the health‑related quality of life (HRQoL) is an important outcome of these diseases. Objective: This study assessed the pattern and predictive factors of HRQoL among patients with hypertension, diabetes and concomitant hypertension and diabetes using the 36‑item short‑form version 2. Patients and Methods: A cross‑sectional study of 1203 patients attending the outpatient clinics of the University of Ilorin Teaching Hospital, Ilorin; the patients were sampled using systematic random sampling methods. Patients were divided into those with hypertension, diabetes and both diseases. The predictors of physical and mental component summaries of HRQoL were analysed using Norm‑based Scoring. The level of significance was set at P < 0.05 and 95% confidence interval. Results: The patients with both diseases have lowest physical HRQoL (45.6), while the diabetic patients have the worst mental HRQoL (39.5). Negative predictors of physical HRQoL across the three groups were: drug regimen (hypertension P < 0.001, diabetes P < 0.001, both P = 0.005), CVD complication (hypertension P < 0.001, diabetes P = 0.025) and accompanying persons (P < 0.001). The positive predictors of physical HRQoL across the three groups were medication adherence (hypertension P < 0.001, diabetes P < 0.001 and both P = 0.002). Similarly, medication adherence was the positive predictor for mental HRQoL across the three groups of patients (hypertension P < 0.001, diabetes P = 0.001 and both P < 0.001). Conclusion: This study provided evidence to show that HRQoL across the three categories of patients in Ilorin, Nigeria, is suboptimal. Drug regimen, medication adherence and support from accompanying persons were important predictive factors of HRQoL.
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    Source identifcation and health risk assessments of heavy metals in indoor dusts of Ilorin, North central Nigeria
    (Journal of Environmental Health Science and Engineering, 2022-01-10) Abdulraheem,Maimuna O.; Adeniran, Jamiu Adetayo; Ameen, Hafsat Abolore; Odediran, Emmanuel Toluwalope; Yusuf,Muhammad-Najeeb O.; Abdulraheem,Khadijat Abdulkareem
    Background and Purpose Exposure to heavy metals (HMs) in indoor dusts is a serious public concern that is linked to a myriad of deleterious health outcomes. The objectives of this study are to estimate the contamination levels of HMs in indoor dusts of diferent residential areas in Ilorin, Nigeria; identify HMs sources in diferent residential areas; and evaluate human health risks of HMs in selected residential areas. Methods Indoor dust sampling was conducted in ten randomly selected from low, medium and high population density residential areas of Ilorin, Nigeria. Ten HMs concentration levels, their health risk implication and the associated potential ecological risks were evaluated. Results The mean concentration levels measured for Fe, Pb, Zn, As, Co, Cr, Cu, Cd, Mn and Ni were 38.99, 5.74, 3.99, 0.08, 2.82, 2.13, 0.47, 0.60, 6.45 and 1.09 mg/kg, respectively. Positive Matrix Factorization (PMF) model was applied to ascer tain sources of HMs in sampled indoor dust. Percentage contribution from oil-based cooking (29.82%) and transportation (29.77%) represented the highest source to HM concentrations among the six factors identifed. The results of the various pollution indices employed showed that Pb, Zn, As, Co, Cr, Cu, Mn and Ni contributed moderately to HMs concentration levels in the sampled dusts. Cd had highest potential ecological risk factor (Eir)of between 160 and 320. The average values of Enrichment Factors (EFs) obtained aside from Fe used as the reference metal, ranged between 8.46 (As) and 2521.61(Cd). Health risk assessment results revealed that children are the most susceptible to the risks associated with HMs bound indoor dust than the adults. The percentage risk contributions of Hazard Quotient via ingestion route (HQing) in Hazard Index (HI) for non-cancer risk of indoor HMs were 93.17% and 69.87% in children and adults, respectively. Likewise, the percentage cancer risks contribution through ingestion pathway (CRing) were higher than cancer risks through inhalation and dermal pathways (CRinh and CRdermal), accounting for 99.84% and 97.04% of lifetime cancer risk in children and adults, respectively. The contamination level of Cd recorded is of great concern and signifes very strong contribution from anthropogenic sources. Conclusion This study has further revealed the levels of HMs in typical African residential settings that could be used by relevant stakeholders and policy makers in developing lasting control measures.