Browsing by Author "Abdulkadir, Mohammed B"
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Item Assessment of the timely administration of birth dose vaccines in Northern Nigeria and associated factors(Ubiquity Press, 2022-07-22) Ibraheem, Rasheedat M; Garba, Bilikisu Ilah; Aliu, Rasaki; Ibrahim, Olayinka R; Bello, Abdulafeez Oyesola; Mohammed, Salihu Sheni; Abdulkadir, Mohammed B; Hashim, Rabiu; Lawal, Ibrahim Magaji; Ahmed, GraceBackground: Lack of a timely receipt of vaccines can cause uncertain immune response and under-vaccination. Hence, timely vaccination is crucial to ensure an infant’s early protection. Objectives: To identify the age of presentation for the birth dose vaccines, vaccine antigens received and factors associated with vaccination presentation by day one in Northern Nigeria. Method: A descriptive cross-sectional study involving 1 952 mother-infant pairs enrolled from 5 different states in Northern Nigeria. Data was collected using a questionnaire including the socio-demographic, antenatal care (ANC), delivery details, birth dates, vaccination presentation and birth vaccine antigens received. Data analysis was done with the SPSS-21 software. Findings: The median age of the infants at presentation for birth vaccines was six (interquartile range 2–16) days. A total of 413 (21.2%) infants were brought by the day of birth (day 0) or the next day (Day one), while one-fifth (20.6%) presented after Day 28. The most frequently received antigen was the Bacille-Calmette-Guerin by 1 781 infants (91.2%), oral polio vaccine 1 703 (87.2%), and hepatitis B vaccine birth dose the lowest at 75.1% (1 565). The commonest reasons for delayed presentations were an ill baby (24.7%) and an ill mother (21.9%). Factors associated with presentation within Day one post-birth were hospital delivery (OR–1.67, 95% CI; 1.28–2.19), firstborn (OR–1.40; 95%CI; 1.02–1.93), Christianity (OR–2.14 95% CI; 1.63–2.81), and mother with tertiary education (OR–1.62, 95% CI; 1.05–2.48). Ibraheem et al. 2 Annals of Global Health DOI: 10.5334/aogh.3743 Conclusion: Timely administration of the birth dose vaccines is low in Northern Nigeria. Furthermore, some babies do not get the required vaccines despite presenting for vaccination due to stockout. Strategies for early neonatal vaccination such as vaccination in hospital suites post-delivery and utilizing relatives/fathers to take the baby for vaccination when a mother is indisposed are imperative.Item Burden and spectrum of paediatric respiratory diseases at a referral hospital in North-Central Nigeria - A five-year review.(Elsevier, 2019-11-13) Ibraheem, Rasheedat M; Aderemi, Jubril A; Abdulkadir, Mohammed B; Johnson, Abdul-Wahab BRIntroduction: Globally respiratory diseases, comprising a broad range of disease conditions due to infectious and non-infectious causes, are a major cause of childhood morbidity and mortality. Thus, identification of the burden of respiratory illness will ensure appropriate interventions towards reducing its attendant morbidity and mor- tality. The study was conducted to identify the burden, spectrum and outcome of respiratory diseases in hos- pitalized children at University of Ilorin Teaching Hospital, North-Central Nigeria. Methods: A retrospective descriptive cross-sectional study involving children admitted through the emergency paediatric unit over five years (January 2013-December 2017) was conducted. Data on demography, diagnosis, co- morbidities and complications, duration of admission, and outcome were collected and analyzed using SPSS 20. Results: Of the total 7012 children admitted, 1939(27.7%) were due to respiratory diseases with a median age of 16 (interquartile range {IQR} 7-36) months. Males were 994(51.3%) and 945(48.7%) females. Infectious dis- eases were the most common cause of admission. Pneumonia (50.1%) and aspiration pneumonitis (5.1%) ac- counted for the highest admissions due to infective and non-infective respiratory diseases respectively. Overall, respiratory diseases accounted for 20.7% (119/574) of the overall mortality among all admissions while the all- respiratory disease mortality was 6.1% (119/1939). The major contributors to mortality were pneumonia, as- piration pneumonitis and tuberculosis accounting for 81(68.1%), 12(10.1%) and nine (7.6%) deaths respec- tively. The median duration of hospital stay was four days [IQR: 2 to 6 days]. A significantly higher proportion of the deaths occurred with four days of admission and 82.4% of the deaths occurred among those aged less than five years. A higher number of females (70, 58.8%) died compared to males (49, 41.2%), p=0.05. Conclusion: Pneumonia and aspiration pneumonitis are major contributors to morbidity and mortality due to respiratory diseases for which interventions towards improving childhood health indices should be prioritized.Item Determinants of timely presentation for birth dose vaccination at an immunization centre in North-central Nigeria.(2019-03-01) Ibraheem, Rasheedat M; Abdulkadir, Mohammed B; Akintola, Moshood A; Adeboye, Muhammed A.N.Background: Timely receipt of immunization is an essential prerequisite to ensure early protection of the child. However, a low proportion of children in Nigeria benefit from the timely administration of the birth dose vaccines. Objectives: These were identification of factors associated with timely presentation and reasons for presentation beyond 24 hours at an immunization centre in Ilorin, Nigeria. Method: A descriptive cross-sectional study involving 480 mother-infant pairs was conducted at an immunization centre. Socio-demographic, antenatal care (ANC) and delivery details, infant’s birthday and day of presentation for vaccination were recorded. Logistic regression was used to identify factors associated with time to presentation within day one. Findings: 239 (49.8%), 421 (87.7%) and 454 (94.6%) babies were vaccinated within days one, seven and 14 respectively. Post-secondary education level of mothers (OR = 3.60; 95% C.I: 1.30–9.91), antenatal care attendance (OR = 9.55; 95% C.I: 1.75–52.12), and hospital delivery (OR = 6.36; 95% C.I: 1.33–30.38) were associated with presentation within day one. Having correct knowledge of the immunization sched- ule increased the odds of early presentation by three times, p = 0.025. The commonest reason for presentation after day one for vaccination was weekend/public holiday delivery identified in 83 (35.2%) mother-infant pairs. Conclusion: Hospital delivery, attendance at antenatal care, postsecondary education and knowledge of the immunization schedule were factors associated with timely presentation for birth dose vaccination. Strategies to improve timeliness of the birth dose vaccination should target babies delivered outside the hospital as well as during weekends in the hospital. Also, inclusion of immunization into the health education curriculum of schools could be beneficial.Item Disseminated tuberculosis in a Nigerian adolescent with Linear IgA Bullous Dermatosis: A case report and review of the literature.(2022-06) Gobir, Aisha; Ariyibi, Solomon O; Ibraheem, Rasheedat M; Johnson, Abdul-Wahab BR; Abdulkadir, Mohammed B; Katibi, Oludolapo S; Adeoye, Peter O; Udoh, E.A; ilesanmi, Omotoyosi; Folaranmi, Olalekan.OLinear IgA bullous dermatosis (LABD) is an auto-immune disease affecting young children and adults, characterized by the linear deposition of IgA at the basement membrane zone with resultant complement activation and a cascade of immune reactions. There is a loss of adhesion at the dermo-epidermal junction and subsequent blister formation. It is a rare disease that has a good prognosis with adequate therapy. However, the underlying depressed immunity associated with the disease may expose them to such infections as tuberculosis. We report the case of an 11-years-old Nigerian female adolescent with LABD, diagnosed at the age of four years but defaulted on fol low-up, who developed disseminated tuberculosis (pulmonary, lymph nodes, abdominal and pericardial effusion) seven years after the appearance of the initial blistering skin lesions. She commenced anti-tuberculosis drugs, steroids, and a tube pericardiostomy for the pericardial effusion. Dapsone was initiated for the LABD during the continuation phase of anti-tuberculosis therapy, with subsequent disappearance of the skin rash within two weeks. WAJM 2022; 39(6): 646– 650.Item Effects of call reminders, short message services (SMS) reminders, and SMS immunization facts on childhood routine vaccination timing and completion in Ilorin, Nigeria.(2021-06) Ibraheem, Rasheedat M; Akintola, Moshood A; Abdulkadir, Mohammed B; Ameen, Hafsat; Bolarinwa, Oladimeji A; Adeboye, Muhammed A.N.Background: Reminders via mobile devices deployed as short message services (SMS) or calls have been identified to be a useful strategy in improving routine immunization uptake in several countries. Objective: To identify the timeliness of appointments with reminders (calls or SMS), SMS health education and the routine care, and the vaccination completion rates in Ilorin, Nigeria. Method: Mother-infant pairs presenting for the first vaccination appointment were randomized into four (three inter- ventions, one control) groups, each consisting of 140 participants. Intervention groups were reminders via calls (A), SMS reminders (B), immunization fact SMS messages (C) and controls on usual care (D). Reminders were made a day before the appointment while SMS immunization facts were sent at five weeks, nine weeks and eight months. Appropriate timing was defined as the scheduled visit ±3 days. Results: The immunization completion rates after the nine months’ visit were 99.2%, 99.3%, 97% and 90.4% for Groups A, B, C and D respectively. Compared with controls, Group A had the highest odds [AOR 8.78 (6.10, 12.63)] of presenting at an appropriate time, followed by Group B [AOR 2.56 (1.96, 3.35)], then Group C [AOR 2.44 (1.87, 3.18)]. Conclusion: Reminders/SMS immunization facts improve vaccination completion rates.Item Knowledge of rotavirus gastroenteritis and its current preventive strategies in children, among healthcare providers in Ilorin, North-Central Nigeria.(2020-05-30) Abdulkadir, Mohammed B; Aderibigbe, Sunday A; Ibraheem, Rasheedat M; Fadeyi, AbayomiContext: Rotavirus is a leading cause of severe gastroenteritis in children aged less than 5 years. Healthcare providers are responsible for implementing strategies for control of rotavirus gastroenteritis. Aims: To determine knowledge of healthcare providers regarding rotavirus gastroenteritis, its burden, management, and prevention. Materials and Methods: The study was a crosssectional descriptive survey of healthcare providers working in facilities caring for children. A selfadministered questionnaire was given to subjects containing questions on demographics and knowledge covering burden of rotavirus gastroenteritis, modes of transmission, age of occurrence, prevention, and rotavirus vaccines. Statistical analysis used: Data analysis was carried out with SPSS version 20. Results: Questionnaires were issued to 75 participants of which 65 (response rate = 86.7%) returned filled questionnaires. Majority (70.8%) of the subjects were females. Subjects included medical doctors (33.8%), nurses (32.3%), community health extension workers (27.7%), and laboratory scientists (4.6%). Most [39, 60.0%] subjects identified rotavirus as the commonest cause of diarrhea and only 21 (32.3%) indicated rotavirus contributed over 30% to the burden of diarrhea in these children. Fecooral route was recognized as a route of transmission by most subjects (95.4%) and 67.7% identified vaccination as a modality for prevention. Only six (9.2%) respondents could name any rotavirus vaccine. None of the demographic or occupational characteristics of the subjects was significantly related to awareness of effective rotavirus vaccines (all P > 0.05). Conclusions: Healthcare providers were aware of rotavirus as a cause of gastroenteritis in underfive children but most had poor understanding regarding its burden, prevention, and existing vaccines.Item Laryngeal tuberculosis: a rare presentation in a Nigerian child with disseminated tuberculosis.(2019) Ibraheem, Rasheedat M; Oladele, Damilola M; Mohammed, Salihu Sheni; Abdulkadir, Mohammed B; Johnson, Abdul-Wahab BR; Omotosho, Abdulwasiu GTuberculosis (TB) remains a ravaging disease, particularly in the low-income countries, with a protean manifestation in children. Thus, a high index of suspicion is the key to clinching the diagnosis when presentation is in a rare form such as laryngeal TB. In this study, the case report of a 10‑year‑old female child with laryngeal TB in the setting of other typical clinical presentation associated with TB is highlighted.Item Nutritional status of primary school children in Ilorin-West LGA, Kwara State, Nigeria.(2021-07-28) Issa, Amdallah; Abdulkadir, Mohammed B; Ibraheem, Rasheedat M; Ibrahim, Olayinka R; Bello, Surajudeen O; Suberu, Habibat D; Sanusi, IbraheemBackground: A proper evaluation of cardiovascular status, with a view to ensuring early diagnosis of cardiac dysfunction and prompt intervention where necessary, is a recognized approach in the management of asphyxiated neonates. Hence, we determined the levels of a cardiac biomarker (troponin I), its relationship with disease severity, and mortality in asphyxiated neonates with hypoxic–ischemic encephalopathy (HIE). Methods: This was a descriptive study that involved 85 asphyxiated, term appropriate‑for‑gestational age newborn babies with HIE (subjects) and 85 healthy controls within the first 72 h of life. Asphyxiated neonates were classified into HIE stages using Sarnat and Sarnat staging. Blood samples were collected between 24 and 72 h of life to determine the level of troponin I using enzyme‑linked immunosorbent assay. The asphyxiated babies were followed up till discharge or death. Results: The median interquartile range level of troponin I in the subjects was higher compared with the controls, 1.26 (0.97–3.16) ng/ml versus 0.79 (0.79–1.42) ng/ml, P < 0. 001. The levels of troponin I in HIE I, HIE II, and HIE III were 1.26 (1.00–2.37) ng/ml, 1.11 (0.86– 2.96) ng/ml, and 3.58 (1.34–5.58) ng/ml, respectively. Nonsurvivors had a higher cardiac troponin I (4.00 [2.30–6.34] ng/ml) compared with survivors (1.21 [0.95– 2.37] ng/ml), P = 0.015. Conclusion: Cardiac troponin I was significantly higher in asphyxiated subjects compared with healthy controls. Elevated troponin I was associated with higher mortality. Troponin I levels in the first 72 h can help as a prognostic indicator of HIE in term babies.Item Reference values for the six-minute walk test in Nigerian adolescents aged 10 to 18 years.(2019-12-30) Abdulkadir, Mohammed B; Ibraheem, Rasheedat M; Akintade, O; Suberu, Halima D; Issa, Amdallah; Alabi, KayodeObjective: To determine baseline six-minute walk distance in Nigerian adolescents and establish its relationship with age, gender and anthropometric parameters. Methods: One hundred and eighty healthy adolescents (10 – 18 years) were recruited from three schools. Six-minute walk test was conducted as described by the American Thoracic Society. Demographic and anthropometric characteristics were related to achieve six-minute walk distance. A mathematical formula for predicting six-minute walk distance was generated. Results: The mean ± SD six-minute walk distance was 590.1 ± 72.02 m and was significantly longer in males (p= 0.001) among adolescents aged 10- 16 years. Age was the only characteristic significantly associated with six-minute walk distance following multiple linear regression analyses. The formulae, [six-minute walk distance = 317.3 + 21.5 x age (years) in males and 117 + 33.0 x age (years) in females] closely approximated to measured six-minute walk distance. Conclusion: This study has derived reference values for 6-minute walk test in adolescents; the use of these reference values should consider age and gender variations.