Comparative study on the antimicrobial activity of partitioned fractions of the stem-bark of Ceiba pentandra (bombacaceae)

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dc.contributor.authorNjinga, N.S.
dc.contributor.authorSule, M.I.
dc.contributor.authorPateh, U.U.
dc.contributor.authorHassan, H.S.
dc.contributor.authorAche, R.N.
dc.contributor.authorAbdullahi, S.T.
dc.contributor.authorDanja, B.A.
dc.date.accessioned2019-10-22T09:09:52Z
dc.date.available2019-10-22T09:09:52Z
dc.date.issued2015
dc.description.abstractDue to the emergence of more and more drug resistance bacteria and the reported antibacterial activity of Ceiba pentandra, the antimicrobial activity of the partitioned ethyl-acetate and n-butanol fractions of the stem-bark of this plant were carried out on the following clinical isolates: Staphylococcus aureus; Streptococcus pyrogenes; corynebacterium ulcereans; Escherichia coli; Salmonella typhi; Shigella dysenterea; Enterococcus aerogenes; Pseudomonas aeruginosa; klebsiella pneumonia and the fungi Trichophytom rubrum, Microsporum sp., Aspergillus fumigatus and Aspergillus niger . Agar diffusion and broth delusion methods were used in this study. The ethyl acetate fraction showedwide spectrumantibacteria activity (with zones of inhibition between 27mmand 37mm)while the n-butanol extract showed activity only against the gram negative bacteria (zones of inhibition between 20mmand 21mm). The MIC ranged from0.65 to 2.5mg/ml and 2.5 to 5mg/ml andMBC ranged from2.5mg/ml and 5 – 10mg/ml for the ethylacetate and n-butanol respectively. Both fractions showed no activity against the fungi used in this study. The preliminary phytochemistry of the ethyl acetate showed the presence of only flavonoid and thismay explain the activity against all the bacteria. The n-butanol showed the presence of carbohydrates, saponins, tannins and cardiac glycoside and the absence of flavonoid and alkaloids. This study justifies the use of this plant in herbalmedicine.en_US
dc.identifier.issn2249-7110
dc.identifier.urihttp://hdl.handle.net/123456789/3002
dc.language.isoenen_US
dc.publisherNitte Universityen_US
dc.subjectantimicrobialen_US
dc.subjectCeiba pentandraen_US
dc.subjectminimuminhibitory concentrationen_US
dc.subjectbacteriaen_US
dc.titleComparative study on the antimicrobial activity of partitioned fractions of the stem-bark of Ceiba pentandra (bombacaceae)en_US
dc.typeArticleen_US

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