38.Prevalence an d predictors of peripheral artery disease among hypertensive patients in a tertiary hospital in north - central Nigeria

Abstract

Objective: The objective of the study was to determine the prevalence of peripheral artery disease and its predictors among hypertensive patients attending the University of Ilorin Teaching Hospital. Design: Hospital-based comparative cross-sectional study. Setting: General outpatient clinic and cardiology clinic Participants:150 hypertensive patients and 150 normotensive patients were recruited. Main outcome measures: The participants were physically examined, and their blood samples were taken for analysis. Ankle-brachial index was determined among the participants using a handheld Doppler machine. Data obtained were analyzed using SPSS 20 computer software package. Results: The prevalence of peripheral artery disease among the hypertensive subjects and normotensive patients were 20% and 3.3% respectively. The predictors of peripheral artery disease were age of the patient (OR, 1.04; 95% CI, 1.01 - 1.08), duration of hypertension (OR, 1.08; 95% CI, 1.02 - 1.15), abnormal body mass index (OR, 1.10; 95% CI, 1.02 - 1.20), low-density lipoprotein cholesterol (OR, 3.41; 95% CI, 1.17 - 9.97) and total cholesterol (OR, 5.56; 95% CI, 2.33 - 13.27). Conclusion: Peripheral artery disease is a common complication among hypertensive patients studied. The predictors of peripheral artery disease among Objective: The objective of the study was to determine the prevalence of peripheral artery disease and its predictors among hypertensive patients attending the University of Ilorin Teaching Hospital. Design: Hospital-based comparative cross-sectional study. Setting: General outpatient clinic and cardiology clinic Participants:150 hypertensive patients and 150 normotensive patients were recruited. Main outcome measures: The participants were physically examined, and their blood samples were taken for analysis. Ankle-brachial index was determined among the participants using a handheld Doppler machine. Data obtained were analyzed using SPSS 20 computer software package. Results: The prevalence of peripheral artery disease among the hypertensive subjects and normotensive patients were 20% and 3.3% respectively. The predictors of peripheral artery disease were age of the patient (OR, 1.04; 95% CI, 1.01 - 1.08), duration of hypertension (OR, 1.08; 95% CI, 1.02 - 1.15), abnormal body mass index (OR, 1.10; 95% CI, 1.02 - 1.20), low-density lipoprotein cholesterol (OR, 3.41; 95% CI, 1.17 - 9.97) and total cholesterol (OR, 5.56; 95% CI, 2.33 - 13.27). Conclusion: Peripheral artery disease is a common complication among hypertensive patients studied. The predictors of peripheral artery disease among these patients were age, duration of hypertension, obesity and dyslipidemia

Description

Keywords

peripheral artery disease, hyertension

Citation

East African Medical Journal 100;1:5542-555.

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