Disseminated tuberculosis in a Nigerian adolescent with Linear IgA Bullous Dermatosis: A case report and review of the literature.

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dc.contributor.authorGobir, Aisha
dc.contributor.authorAriyibi, Solomon O
dc.contributor.authorIbraheem, Rasheedat M
dc.contributor.authorJohnson, Abdul-Wahab BR
dc.contributor.authorAbdulkadir, Mohammed B
dc.contributor.authorKatibi, Oludolapo S
dc.contributor.authorAdeoye, Peter O
dc.contributor.authorUdoh, E.A
dc.contributor.authorilesanmi, Omotoyosi
dc.contributor.authorFolaranmi, Olalekan.O
dc.date.accessioned2023-01-09T09:23:06Z
dc.date.available2023-01-09T09:23:06Z
dc.date.issued2022-06
dc.description.abstractLinear IgA bullous dermatosis (LABD) is an auto-immune disease affecting young children and adults, characterized by the linear deposition of IgA at the basement membrane zone with resultant complement activation and a cascade of immune reactions. There is a loss of adhesion at the dermo-epidermal junction and subsequent blister formation. It is a rare disease that has a good prognosis with adequate therapy. However, the underlying depressed immunity associated with the disease may expose them to such infections as tuberculosis. We report the case of an 11-years-old Nigerian female adolescent with LABD, diagnosed at the age of four years but defaulted on fol low-up, who developed disseminated tuberculosis (pulmonary, lymph nodes, abdominal and pericardial effusion) seven years after the appearance of the initial blistering skin lesions. She commenced anti-tuberculosis drugs, steroids, and a tube pericardiostomy for the pericardial effusion. Dapsone was initiated for the LABD during the continuation phase of anti-tuberculosis therapy, with subsequent disappearance of the skin rash within two weeks. WAJM 2022; 39(6): 646– 650.en_US
dc.identifier.citationGobir, A.A., Ariyibi, S.O., Ibraheem, R.M., Johnson, A.R., Abdulkadir, M.B., Katibi, O.S, Adeoye, P.O., Udoh, E.A, Ilesanmi, O.N., & Folaranmi, O.O. (2022): Disseminated tuberculosis in a Nigerian adolescent with Linear IgA Bullous Dermatosis: A case report and review of the literature. West African Journal of Medicine, 39(6), 646-650.en_US
dc.identifier.issn0189 - 160X
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/20.500.12484/8216
dc.language.isoenen_US
dc.titleDisseminated tuberculosis in a Nigerian adolescent with Linear IgA Bullous Dermatosis: A case report and review of the literature.en_US
dc.typeArticleen_US

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