Sero-prevalence and risk factors associated with hepatitis B surface antigen (HBsAG) amongst patients in BIU, Borno State, Nigeria
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Date
2011-10-14
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Journal of Public Health and Epidemiology
Abstract
A survey of hepatitis B virus (HBV) amongst patients attending Abott Medical Centre, Biu in Borno State
was conducted to determine the prevalence and evaluate risk factors associated with hepatitis B spread
following the growing concern over the increasing epidemics in the country. Four hundred and seventy
two (472) patients were screened for HBV using the rapid chromatographic immunoassay for
quantitative detection of HBV antibodies in serum. Out of these 472 patients, 136 (28.8%) were positive
for HBsAg, of which 89 (65.4%) were men and 47 (34.6%) were females. The highest positive reactors
were found in patients below the ages of 30 years (70.6%). Age and sex were statistically significant
(P<0.01) by chi-square test. Risk factor evaluation using structured questionnaire and in-depth
anonymous discussion revealed occupational type/profession, marital status, level of education and
socio-cultural behaviors as contributing factors to the spread of HBV. In conclusion, this study
provides preliminary information on the prevalence and associated risk factors of HBV in these carriers
within Biu Local Government Area (LGA) which suggests the possibility of localized hepatitis
pandemic. Hence, the need for promotion of health awareness campaigns, prophylactic vaccination,
and most importantly the need to maintain active and continuous surveillance of this disease.
Screening for HBV, counseling, testing and supportive treatment are therefore recommended for all
patients visiting any health centre.
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Keywords
Sero-prevalence, hepatitis B surface antigen, chromatographic immunoassay, risk factors, Abott medical centre, Biu