Selected Liver Function Indices in Male Farmers Exposed to Pesticides
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Date
2023-06
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Publication of Faculty of Health Sciences Al-Hikmah University Ilorin, Nigeria
Abstract
Introduction: Exposure to environmental toxins and ensuing liver health outcomes has
attracted global attention. This study was aimed at assessing the liver function indices
among farmers exposed to pesticides.
Methodology: This research was carried out on 130 apparently healthy male participants
aged 18 years and above. The participants were randomly selected for this comparative
cross-sectional study. The participants were further divided into two groups; the
Pesticide-exposed group and the control group (non-exposed). Demographic
characteristics of the participants were obtained by standard methods. Five milliliters of
fasting blood samples were collected from each participant after an overnight fast (8 to
12 hours). A portion of the blood sample was dispensed into plain tubes for the estimation
of serum Aspartate aminotransferase, alanine aminotransferase, albumin, and total
protein. Statistical Package for Social Science (SPSS) 25.0 software was used for
statistical analysis.
Results: The results from this study suggest that exposure to pesticides may have adverse
effects on the liver as evidenced in the observed significant (p ≥ 0.05) increase in serum
AST, ALT, and decreased Albumin and Total protein values in the pesticide-exposed
group when compared with the normal control.
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Pesticide Farmers Liver Function Indices