Familial adenomatous polyposis syndrome with colorectal cancer in two Nigerians: a report of two cases and review of literature
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Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
African field epidemiology network (AFENET)
Abstract
Familial adenomatous polyposis syndrome is a rare condition characterized by the presence of numerous adenomatous polyps in the
gastrointestinal tract and associated with risk for colorectal cancer. The disease is scarcely reported in Nigeria and this is the index report in Ilorin.
Two cases were clinically diagnosed in our facility. They both presented with gastrointestinal bleeding and numerous rectal and colonic polyps were
identified at colonoscopy. Histological examination of the polyps in both cases revealed features in keeping with adenomatous polyps. This report
highlights the occurrence of this precancerous condition.
Description
Keywords
Familial adenomatous polyposis syndrome, adenomatous polyps, colorectal cancer, gastrointestinal bleeding
Citation
Bojuwoye, M.O., Olokoba, A.B., Ogunlaja, O.A., Agodirin, S.O., Ibrahim, O.K., Okonkwo, K.C. & Aliyu, A.M. (2018). Familial adenomatous polyposis syndrome with colorectal cancer in two Nigerians: a report of two cases and review of literature. The Pan African Medical Journal. 30: 6. A publication of the African field epidemiology network (AFENET). Available online at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093594