Anthelmintic Potency of Carica papaya seeds against Gastro-intestinal Helminths in Red Sokoto goat.
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Date
2018
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Journal ISSN
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Publisher
University of Peradeniya, Sri Lanka.
Abstract
The comparative studies on anthelmintic potency of
Carica papaya seeds was investigated in naturally infected Red
Sokoto goats. Forty Red Sokoto goats (average 12 ± 0.25 kg body
weight) infected naturally with helminthes were used to compare
anthelminthic potency of Carica papaya seeds in aqueous and
crude extract forms and Thiabendazole treatment against intestinal
worms. The animals were randomly assigned into four treatment
groups (A, B, C and D) consisting of 10 Red Sokoto goats
per group. The animals in group A were not treated (negative
control) while B undergone thiabendazole anthelmintic treatment
(positive control). Groups C and D were given the powdery and
aqueous forms of C. papaya seed extract via feed at 300 mg/
kg body weight/day and at 1:10 ml (w/v) of water respectively
for 3 days. Before anthelmintic treatments and 1st and 2nd weeks
after administering the anthelminthics, faecal and blood samples
were collected for parasitological and haematological analysis.
Data collected were subjected to one-way ANOVA. Treatments
of both aqueous and powdery forms of C. papaya seed extract
resulted a significant increase (p < 0.05) in packed cell volume
(PCV), red blood cell (RBC) and haemoglobin concentration and
lymphocyte counts. Conversely, there was significant (p > 0.05)
decrease in the eosinophil counts. The reduction in the faecal
egg counts of helminth when C. papaya seed extracts applied
was significantly (p < 0.05) comparable to those obtained for
Thiabendazole treatment. However, the efficacy of aqueous form
of C. papaya seed extract was more significant (p < 0.05) than
the crude (powdery) extract administered via the feed. The study
therefore concludes that C. papaya seed extracts have comparable
anthelmintic potency to Thiabendazole and that aqueous forms
were more efficient than powdery forms when administered in
Red Sokoto goats as an alternative to anthelmintic to synthetic
dewormers in rural areas in controlling helminthosis
Description
Carica papaya seeds, Red Sokoto goats, Helminths,
Anthelmintics, Thiabendazole.
Keywords
Citation
Ameen et al 2018 Ceylon Journal of Science 47(2): 137-141