Browsing by Author "Shehu, A.,"

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    Chemical constituents from the leaf extracts of scleria depressa (C.B Clarke) Nelmes with its antioxidant and anti-inflamatory activity.
    (Faculty of Physical Sciences, University of Ilorin., 2018) Oguntoye, S.O.,; Hamid, A.A.,; Jimoh, A.,; Abdulrauf, A.T.,; Bale, M.I.,; Lawal, A.Z.,; Shehu, A.,; Faturoti, I. O.,; Oluwo, A. C. &; Olodu , J. O.
    Antioxidant and antiinflammatory activity of the extracts of Scleriadepressa leaf part were investigated in this study. The leaf part of Scleriadepressa were dried, ground, weighed, and exhaustively extracted with n-hexane, ethylacetate and methanol. GC-MS analysis of the extracts was carried out to know the compounds present in the extracts as well as their molecular formula. These extracts of the plant were evaluated for antioxidant and antiinflammatory activity using peroxide scavenging, lipoxidase and membrane stabilization. Hexane, Ethylacetate and methanol extracts of the Scleriadepressa leaves exhibited antioxidant activity on peroxide radicals at different concentrations ranging from 10-150 µg/mL, using ascorbic acid as standard antioxidant. Ethylacetate and methanol extracts of the plant’s leaves possessed antioxidant activity by exhibiting peroxide free radical scavenging with IC50of 106.23 and 148.79µg/mL respectively, using peroxide antioxidant assay. The hexane extract shows inhibition that is more pronounced compared to that of ethylacetate for the antiinflammatory activity while methanol extract of the plant’s leaves shows activity higher than that of hexane and ethylacetate for the anti-inflammatory activity. The GC-MS analysis shows the presence of 13 compounds for hexane extract with Carvomenthol,( an α-Terpenol) and 1,2,3-Trimethylbenzene being the abundant compounds with %abundanceof 23.78% and 19.20% respectively, while ethylacetate extract revealed 19 compounds with 1,2- Benzenedicarboxylic acid,bis(2-methylpropylester), and 4,7-dimethylundecane with corresponding % abundance of 24.56% and 16.83% being the abundant compound also the GC-MS analysis of methanol extract of Scleriadepressa leaves showed the presence of 11 compounds. The compound with highest abundance is Methyl9-octadecenoate, with %abundance of 69.86 and retention time of 14.714.
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    Chemical constituents, antibacterial, antifungal and antioxidant activities from the leaf extracts of Drynaria laurentii. Journal of Phytomedicine and Therapeutics
    (National Institute for Pharmaceutical Research Development, 2022) Shehu, A.,; Issa S.B.,; Lawal, A.Z.,; Egharevba, G.,; Ojo, J. B,; Salami, L.B,; Taiwo, L.O.,; Yusuf, S.A,; Adeyemo, J.,; Bello, O.,; Bale, M.I. &; Hamid, A.A.
    The chemical constituents of weighed, air-dried leaf samples of a native Nigerian plant, Drynaria laurentii, were examined. The bioactivity of n-hexane, ethyl acetate and methanol extracts of the plants were tested against ten (10) strains of bacteria and fungi, and their antioxidant activities and antimicrobial properties were studied. Ethyl acetate extract of Drynaria laurentii leaves exhibited 2,2-diphenyl-1-hydrazine (DPPH) radical scavenging property with Inhibition Concentration at 50% (IC50) of 298.912 μg/mL while hexane and methanol extracts of the plant showed no significant antioxidant activity. From the antimicrobial study, the methanol extract of the plant inhibited the growth of all the test organisms at all concentrations while the n-hexane extract specifically inhibited the growth of the test bacteria at 200-25 mg/mL and have low inhibitory effects on all the test fungi. Meanwhile, the ethyl acetate extract inhibited the growth of all the test bacteria from a range of 200–12.5 mg/mL and all the test fungi at the range 200-25 mg/mL. However, some bacteria (6.25 mg/mL) and fungi (12.5-6.25 mg/mL) displayed resistance to the ethyl acetate extract of the plant. The Gas Chromatography-Mass Spectrometry (GC-MS) characterisation of n-hexane leaf extract of D. laurentii afforded nineteen (19) compounds with heptadecanal constituting 15.64% as the most abundant constituent of the extract. Ethyl acetate and methanol extracts of the plant afforded eighteen (18) and seventeen (17) compounds with γ-sitosterol (14.34%) and clionasterol (15.32%) as the abundant constituents in both extracts respectively.
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    Effect of computer animation instruction on senior school students' learning outcomes in atomic and nuclear Physics, Kwara State, Nigeria
    (Faculty of Natural and Applied Sciences, Ignatius Ajuru University of Education, Port Harcourt, Rivers State, Nigeria, 2024) Shehu, A.,; Akanbi A. O.; Yahaya, Q.; Yahaya, W. O.; Adeniyi, G. I.; Abdulkadir, A. S.
    This study investigates the impact of computer animation instructional strategy on senior school students' performance and retention in atomic and nuclear physics in Kwara State, Nigeria. The researchers used a pre-test, and post-test design with a non-randomized, non-equivalent control group. The target population comprised all SS3 physics students in Kwara State. Two co-educational public senior secondary schools were selected from two out of the sixteen Local Government Areas in Kwara State, employing a sampling technique that involves multiple stages. Two intact classes, comprising 177 students were involved in the study. The instruments used for data collection were the Atomic and Nuclear Physics Performance Pre-Test (ANPPT I), Atomic and Nuclear Physics Performance Post-Test (ANPPT II), and Atomic and Nuclear Physics Retention Test (ANPRT). The instruments' reliability, carried out by experts, was 0.87. The research questions were answered using mean and standard deviation, and the null hypotheses were tested using the t-test and ANCOVA. The study's findings indicated a significant difference in mean scores between the experimental and control groups, which favoured the experimental group. Additionally, there was a significant difference in mean retention scores between the experimental and control groups, with the experimental group exhibiting higher scores. Notably, neither score level nor gender had a significant impact on either performance or retention. Based on the results, it was suggested that educational authorities at both the Federal and State Ministries of Education should organize workshops and seminars for teachers, focusing on utilizing computer animation as an instructional strategy to enhance students' performance in physics.