Browsing by Author "Salami, A.K"
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Item Etiology, clinical characteristics, and management of pleural effusion in Ilorin, Nigeria.(Nigeria Medical Association, 2017) Adeoye, O.P; Johnson, 'W.B.R; Desalu, O.O; Ofoegbu, C.P; Fawibe, E.A; Salami, A.K; Akin-Dosunmu, A; Ibraheem, R.MBackground: Pleural effusion (PE) is a primary manifestation or secondary complication of many disorders. This study reviews the pattern and management of PE in a Nigerian hospital. Materials and Methods: The medical records of 213 patients with clinical diagnosis of PE over a period of 3 years were reviewed. Results: PE accounted for 0.5% of the total hospital admissions. The most common cause of PE was tuberculosis (TB) (32.9%), followed by malignancy (29.1%) and pneumonia (15.0%). The male to female ratio was 1.3:1. TB was the leading cause of effusion in males, while it was malignancy in females. Pneumonia accounted for 61.9% of PE in preschool age and 66.7% in school age. Breathlessness (50.0%), cough (39.4%), and chest pain (24.9%) were the common presentations. Most (90.1%) of them were exudative effusion and with half in the right lung. Chest radiography (91.6%), pleural fluid for Ziehl–Neelsen stain (74.7%), cytology (59.2%), and tissue biopsy (57.8%) were the common diagnostic investigations. The majority (92.0%) had closed thoracostomy tube drainage, while 9.9% had chemical pleurodesis. The intra-hospital mortality was 10 (4.7%). Conclusion: TB, malignancy, and pneumonia are the leading causes of PE. A multidisciplinary approach is needed for optimal management.Item Normal CD4 Count Range among Healthy Nigerian Population in Ilorin(2014) Afolabi, J.K.; Fadeyi, A; Desalu, O O.; Durotoye, I. A; Fawibe, A. E.; Adeboye, M.A.N; Olawumi, H.O; Babatunde, A.S; Ernest, S.K; Aderibigbe, S.A; Saadu, R; Salami, A.K; Aboyeji, A.PBackground: For the establishment and monitoring of the immune status, CD4 count is critical. Objectives: To determine the CD4 count range of apparently healthy Nigerians resident in Ilorin and compare with the national value. Methods: An automated blood analyzer was used to determine the full blood count and CD4 count. The percentage of CD4 count was derived by using other variables. Results: Of the 1205 participants, the reference CD4 count (percentage of CD4) range for adult was 400 to 1288 cells/mm3 (19%-48%) and for children was 582 to 3652 cells/mm3 (17%-50%). CD4 count and percentage of CD4 were significantly (P ¼ .001) higher in females than in males, and the CD4 count declined significantly with increasing age (r ¼ .174, P .0001). The percentage of CD4 count shows less variation with age (r ¼ .051, P ¼ .076). Adult residents of Ilorin had significantly lower absolute mean CD4 count (808 + 260) than that of the national reference values of 847.0 + 307.0 cells/mm3 (P ¼ .001). Conclusion: We therefore advocate the use of CD4 count range derived in this study is lower than that of the national reference values.Item REFERENCE VALUES OF HAEMATOLOGICAL PARAMETERS OF HEALTHY ADULTS IN THE NORTH CENTRAL ZONE OF NIGERIA(Kenya Medical Association, 2015-08) Olawumi, H.O.; Durotoye, I A.; Afolabi, J.K; Desalu, O.O; Aderibigbe, S.A; Babatunde, A.S; Ernest, S.K; Fawibe, A.E; Salami, A.K; Saadu, R; Adeboye, MAN; Aboyeji, A.PBackground: Haematological parameters differ from one population to another due to several factors. To determine the clinical implication of the blood parameters of an individual in the state of health or disease, we need to have the knowledge of the normal reference range for that locality. Objectives: To determine the reference values of haematological parameters of apparently healthy adults in Ilorin. Design: A descriptive cross sectional study. Setting: Ilorin, North Central zone of Nigeria Subjects: Nine hundred and ten (443 males and 467 females) randomly selected normal, HIV negative individuals aged 18-65 years Results: The red blood cell count, Haemoglobin concentration, PCV and MCHC were significantly higher among males than females while the platelet count, total WBC count and absolute neutrophil count were significantly higher in females than in males. There was however no significant gender difference in the values of MCV, MCH and absolute lymphocyte count. The normal reference values obtained in this study were notably different from those that are used currently in the hospital. Conclusion: The normal reference value obtained in this study was notable different from those that are currently used in the hospital. These findings will have clinical implications regarding the adjustment of our current reference values and definitely add value to the management of patients in this part of the country.Item Sero-Prevalence of Hepatitis B and C among mentally ill patients attending a tertiary hospital in Nigeria(Annals of African Medicine Society and Usman Danfodiyo University Teaching Hospital, Sokoto, Nigeria, and is affiliated to the Usman Danfodiyo University Teaching Hospital, Sokoto, Nigeria,, 2021-03-23) Durotoye, I A.; Issa, B.A; Fadeyi, A; Yussuf, A.D; Salami, A.K; Shittu, O.A; Ajiboye, P.O; Olawumi, H.O.; Adegunloye, O.A; Nwabuisi, C.; Sulyman, D.Background: Mentally ill persons are vulnerable to sexually transmitted infections including hepatitis B and C because of their high level risky behaviors. This study is aimed at establishing the sero-prevalence of hepatitis B and C among the mentally ill individuals (MII) attending Psychiatric clinic of the University of Ilorin Teaching Hospital (UITH), Nigeria since it has not been documented. Methods: A total of 350 MII were recruited. HBsAg testing was by immunoassay test strip (Grand Medical DiagnosticR USA) while hepatitis C was tested by commercially prepared kits from ACON,R USA. Healthy adults who presented as donors in the Blood Bank of the hospital were used as controls. Results: A total of 700 participants including 350 MII and 350 blood donors (BDs) were recruited for the study. The mean ages of MII and control participants were 36.5 ± 12.3 and 31.4 ± 8.3, respectively.The sero-prevalence of hepatitis B and C among patients with mental illness was 10.0 and 12.6%, respectively, as compared to 10.9% and 1.1% of the blood donors. There was a significant difference in the prevalence of HCV among mentally ill when compared with the blood donors (P = 0.001, 2 = 33.97; OR (CI) =12.44 (5.33‑29.03). Conclusion: Mentally ill patients attending UITH were significantly infected with hepatitis C virus. There is need for interventional measures to reduce the prevalence of hepatitis C among the mentally ill population such as health education and early screening of mentally ill in our setting.Item SERO-PREVALENCE OF HEPATITIS B AND C AMONG MENTALLY ILL PATIENTS ATTENDING A TERTIARY HOSPITAL IN NIGERIA(Annals of African Medicine Society and Usman Danfodiyo University Teaching Hospital, Sokoto, Nigeria, and is affiliated to the Usman Danfodiyo University Teaching Hospital, Sokoto, Nigeria,, 2014) Durotoye, I A.; Issa, B.A; Fadeyi, A.; Yussuf, A.D; Salami, A.K; Shittu, O.A; Ajiboye, P.O; Olawumi, H.O.; Adegunloye, O.A; Nwabuisi, Charles; Sulyman, D.Background: Hepatitis B and C are of global concern and Nigeria is a high endemic zone for the viruses. Persons with severe mental illness have a greater vulnerability to sexual transmitted infections including hepatitis B&C due to risky behaviour they engage in. The aim of this study is to determine the sero- prevalence of hepatitis B and C among persons with mental illness (MII) and compare them with blood donors (BDs) at University of Ilorin Teaching Hospital (UITH), Nigeria. Methods: A prospective cross-sectional study conducted over a period of 1year, starting from June, 2010, involving 350 each of BDs and MII in an out-patients department of UITH. HBsAg testing was by a one stage hepatitis B surface antigen test strips, while hepatitis C was tested using commercially prepared kits from ACON, USA. Result: A total of seven hundred participants including 350 patients with MII and 350 blood donors (BDs) were recruited for the study. Most 324(92.6%) and 349 (99.7%) were of the age range ≤55 years. There were 179(51.2%) males and 171(48.8%) females. More married BDs live with their spouses (99.0%) and had higher education than MII. Unemployment rate was higher among MII than BDs. The sero-prevalence of Hepatitis B and C among patients with mental illness (MII) was 10.0% and 12.6% respectively as compared to a sero-prevalence of 10.9% and 1.1% in the blood donors. Conclusion: The prevalence of hepatitis B infection was similar in both subjects (MII) as well as in the blood donors but, in contrast however was higher prevalence of hepatitis C in the MII (p=0.001). Routine screening of MII for hepatitis B and C is advocated to control the complications that may arise from these diseasesItem Sero-Prevalence of Syphilis among Patients with Mental Illness: Comparison with Blood Donors(Osun State University, 2014) Issa, B.A; Fadeyi, A.; Durotoye, I A.; Yussuf, A.D; Salami, A.K; Shittu, O.A; Ajiboye, P.O; Olawumi, H.O.; Adegunloye, O.A; Mwabuisi, C.; Sulyman, D.BACKGROUND: Mentally ill individuals (MII) are at risk of acquiring syphilis and other sexually transmitted infections. This study aimed at determining sero-prevalence of syphilis among MII and compare them with voluntary blood donors (VBD) at University of Ilorin Teaching Hospital (UITH), Nigeria. METHODS: A cross-sectional study done between June, 2010 and June 2011, and involving 350 each of VBDs and MII in and out-patients of UITH. Serological test was done using venereal disease research laboratory (VDRL) and the Treponema Pallidum Haemagglutination (TPHA) kit. RESULTS: Of the 700 subjects, 324 (92.6%) MII, and 349 (99.7%) VBDswere <55 years; 71 (21.4%) MII were Civil Servants compared with 96 (27.4%) VBDs. Significantly more VBDs had higher education than MII (185 or 52.9%, and 140 or 40% respectively). Christians constituted the majority (176 or 50.3%) among MII, and Muslims (210 or 60%) among VBDs. Significantly more married VBDs (204/206 or 99.0%) live with spouses; more VBDs consumed alcohol (37 or 10.6%), smoked (19 or 5.4%), and engaged in extramarital sex (105 or 30.0%). Significantly more MII had blood transfusion (40 or 11.4); engaged in sex trade (12 or 3.4%); and more syphilis prevalence (5.4%). In addition, more syphilitic MII smoked(18 or 94.7%); and all syphilitic MII had psychotic disorders. CONCLUSION: The prevalence of syphilis in MII is significantly higher than among VBDs. Routine screening of MII is advocated to stem this problem.WAJM 2013; 32(2):210–215.