Normal CD4 Count Range among Healthy Nigerian Population in Ilorin
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Date
2014
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Abstract
Background: For the establishment and monitoring of the immune status, CD4 count is critical. Objectives: To determine
the CD4 count range of apparently healthy Nigerians resident in Ilorin and compare with the national value. Methods: An
automated blood analyzer was used to determine the full blood count and CD4 count. The percentage of CD4 count was
derived by using other variables. Results: Of the 1205 participants, the reference CD4 count (percentage of CD4) range for
adult was 400 to 1288 cells/mm3 (19%-48%) and for children was 582 to 3652 cells/mm3 (17%-50%). CD4 count and
percentage of CD4 were significantly (P ¼ .001) higher in females than in males, and the CD4 count declined significantly with
increasing age (r ¼ .174, P .0001). The percentage of CD4 count shows less variation with age (r ¼ .051, P ¼ .076).
Adult residents of Ilorin had significantly lower absolute mean CD4 count (808 + 260) than that of the national reference
values of 847.0 + 307.0 cells/mm3 (P ¼ .001). Conclusion: We therefore advocate the use of CD4 count range derived in
this study is lower than that of the national reference values.
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Keywords
CD4 count, range, T lymphocyte, Nigeria
Citation
Afolabi, J.K., Fadeyi, A., Desalu, O.O., Durotoye, I.A., Fawibe, A.E., Adeboye, M.A.N., Olawumi, H.O., Babatunde, A.S., Ernest, S.K., Aderibigbe, S.A., Saadu, R., Salami, A.K., & Aboyeji, A.P. (2014). Normal CD4 Count Range among Healthy Nigerian Population in Ilorin. Journal of the International Association of Providers of AIDS Care (JIAPAC), 16(4):359-365.