Browsing by Author "Panti, Abubakar A."

Now showing 1 - 13 of 13
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    Assisted Reproduction Technology: Comparison of Clinical outcomes between day 3 and day 5 embryo transfer
    (College of Medicine KLE University, Belgaum, India, 2018) Omokanye, Lukman O.; Saadu, L.O.; Olatinwo, Abdulwaheed O.; Biliaminu, S.A.; Durowade, K A.; Panti, Abubakar A.; Salaudeen, A.G.
    BACKGROUND: Embryo transfer (ET) is a critical step in in vitro fertilization (IVF). Selecting the day of transfer for achieving the desired outcomes has been a great challenge. AIMS AND OBJECTIVES: The aim of this study was to compare the pregnancy rates of day 3 and day 5 ET in assisted conception. MATERIALS AND METHODS: This is a longitudinal prospective study of 122 eligible patients that underwent assisted reproduction program in our facility. All patients had controlled ovarian hyperstimulation using antagonist protocol. Patients with four or more zygotes were randomly allocated on day 1 to either day 3 or 5 transfers (58 vs. 64 patients). Fertilization was achieved through conventional IVF. Zygotes were kept in a single‑step medium (Global total®) for day 3 and 5 transfers, respectively. The morphologically best two or three embryos or blastocysts were chosen for transfer in both groups. RESULTS: The overall clinical pregnancy and live birth rates for both groups were 40.2% and 33.6%. There was no statistically significant difference between day 3 and day 5 transfer regarding clinical pregnancy rates (36.2% vs. 43.8% [P = 0.51]), live birth rates (27.6% vs. 9.1% [P = 1.0]), twinning rates (18.8% vs. 20% [P = 1.0]), and rates of early pregnancy loss (8.6% versus 4.7% P = [0.2]). CONCLUSION: In this study, the clinical outcomes of blastocyst transfer are similar to day 3 ET. This underscores the need for patient selection for the choice of days of ET. Further controlled randomized prospective studies with larger sample sizes are recommended.
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    Assisted Reproductive Technology: Experience from a Public Tertiary Institution in North Central Nigeria
    (Association of Fertility and Reproductive Health, 2016) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Saadu, L.O.; Biliaminu, S.A.; Durowade, K A.; Panti, Abubakar A.
    Background: According to the World Health Organization, more than 180 million couples globally suffer from infertility, the majority being residents of developing countries. Assisted reproductive technologies (ARTs) offer a chance at parenthood to couples, who until recently would have had no hope of having a “biologically related” child. Objectives: This study aimed to determine pregnancy outcomes following assisted conception. Materials and Methods: This is a prospective study of 104 clients who underwent the procedure of ART between January 1, 2012 and December 31, 2016 at the ART unit of University of Ilorin Teaching Hospital, Ilorin, Nigeria. Results: Of the 510 clients who had infertility consultation at the ART clinic, 104 (20.4%) underwent ART procedures. The patients aged 27–46 years with a mean age of 33 ± 4.0 years. More than half (58.7%) had primary infertility. Their duration of infertility ranged from 1 to 20 years (4.6 ± 2.9 years). Majority (81.7%) had conventional in vitro fertilization while 19 (18.3%) had intracytoplasmic sperm injection. Thirteen (12.5%) cases of cycle cancellation and 11 (11.7%) cases of mild‑to‑moderate ovarian hyperstimulation syndrome were recorded. The clinical pregnancy rate per cycle started was 39.4%. However, 9/41 (22%) resulted in spontaneous miscarriages and 32 (6 sets of twin, 25 singleton, and 1 high‑order multiple births) were successfully delivered, giving a live birth rate per cycle started of 30.8%. Pregnancy outcomes were not significantly affected by age of the women, types of infertility, and duration of infertility (P > 0.05). Conclusion: The outcomes of ART procedures in a resource‑limited country like ours are encouraging. This underscores the need to encourage ART in public tertiary institutions in Nigeria through the support of government and nongovernmental organizations for the benefit of infertile couples who were hitherto hopeless.
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    Clomiphene Resistant Polycystic Ovarian Syndrome: Analysis of Outcomes following Laparoscopic Ovarian Drilling in Infertile Women in Ilorin, North-Central, Nigeria.
    (African Health Research Organization, 2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Panti, Abubakar A.; Ibrahim, S.; Oyedepo, O.O.; Ige, O.A.; Adegboye, M.B.
    Background: Laparoscopic ovarian drilling (LOD) is one‑off treatment modality for clomiphene citrate (CC)‑resistant polycystic ovarian syndrome (PCOS) avoiding the need of medical therapy and its attendant complications. Aims and Objectives: This study aimed at determining the efficacy of LOD in women with anovulatory infertility secondary to CC‑resistant PCOS and factors influencing reproductive outcomes. Materials and Methods: A cross‑sectional study of infertile women who underwent LOD on account of CC‑resistant PCOS between January 2012 and December 2015 at a tertiary institution. Results: Patients aged 24–38 years (29.7 ± 3.6 years) and their body mass index (BMI) ranges from 20 to 35 (26.3 ± 4.3). The majority (90.5%) were nulliparous. Most (61.3%) had primary infertility. Their duration of infertility ranges from 1 to 13 years (4.3 ± 2.7) and ovarian volume ranges from 10 to 24 cm3 (mean, right ovary = 15.2 ± 3.2; left ovary = 16.3 ± 3.2). The number of drills per ovary ranged from 4 to 14 (mean, right ovary = 7.4 ± 2.1; left ovary = 7.3 ± 2.1) and the luteinizing hormone/follicle stimulating hormone (LH)/FSH ratio ranges from 2 to 6 (3.2 ± 1.4). All achieved spontaneous resumption of menses and ovulation with mean durations of 4.0 ± 1.8 days and 5.3 ± 3.2 weeks, respectively. Eighty‑three (60.6%) clinical pregnancies were recorded, of which 68 (49.6%) resulted to live births (61 singletons and 7 twin births) and 14 (10.2%) early first trimester miscarriages. The mean time interval from LOD to pregnancy was 4.4 ± 1.1 months. There was a significant association between BMI, duration of infertility, FSH/LH ratio, and pregnancy outcomes (P < 0.05). Conclusion: LOD is the most preferred treatment modality for CC‑resistant PCOS as it resulted in higher pregnancy rate.
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    Controlled ovarian stimulation protocols in assisted conception: agonist versus antagonist in normal responders
    (African Journal of Infertility and Assisted Conception, 2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Saadu, L.O.; Biliaminu, S.A.; Durowade, K A.; Panti, Abubakar A.; Salaudeen, A.G.
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    The Determinants of Utilization of Insecticide Treated Nets Among Pregnant Women Attending Antenatal Clinic at University of Ilorin Teaching Hospital, Ilorin, Nigeria
    (Biomedical Science Direct Publication, 2012) Omokanye, Lukman O.; Saidu, R.; Olatinwo, Abdulwaheed O.; Jimoh, A.A.G.; Salaudeen, A.G.; Balogun, O.R; Ijaiya, M.A.; Panti, Abubakar A.
    Background and Objective: Malaria remains a disease of public health importance in the developing countries. The purpose of this study was to determine factors influencing the utilization of ITNs among pregnant women attending antenatal clinic at the UITH, Ilorin. Materials and Methods: This study was a cross-sectional survey of pregnant women carried out in the antenatal clinic of UITH. The subjects were selected at booking and administered questionnaire. Data were analyzed using Epi-Info software version 3.4.1 of computer. Results: The findings were that 85.2% knew about ITNs and 29.6% did not know where to obtain ITNs. About 74% did not know the cost of ITNs, and 81.5% and 79.8% were of the opinion that ITNs are used to protect against mosquito bites and effective in prevention of malaria respectively. One third (33.7%) of respondents had ever used ITNs. The reasons for non-utilization of ITNs were among others, lack of knowledge, lack of interest, unavailability and use of other methods of prevention. About half of ITNs users used it every day and only 7.9% have been using it for over three years. Statistical analysis showed that marital status, parity, and education had significant influence on utilization of ITNs, where as age and gestational age at booking did not. Conclusion: ITNs coverage is abysmally low among the most vulnerable group. There is need for government to increase enlightenment campaign and intensify advertisement on media that would inform and educate individuals about the usefulness of ITNs
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    Ectopic pregnancy at Usmanu Danfodiyo University Teaching Hospital Sokoto: A ten year review
    (Association of Resident Doctor, Ahmadu Bello University Teaching Hospital, Zaria, 2012) Panti, Abubakar A.; Ikechukwu, N.E.; Omokanye, Lukman O.; Yakubu, A.; Egondu, S.C.; Tanko, B.A.
    Background: Ectopic pregnancy continues to be a life threatening gynaecological emergency. Objective: To determine the incidence, pattern of presentation and management of ectopic pregnancy in UDUTH Sokoto. Materials and Methods: This is a retrospective study of cases of ectopic pregnancy managed in the gynaecological unit of UDUTH from 1st January 2002 to 31st December 2011. Results: During the period, there was a total of 20,095 deliveries and 7,254 gynaecological admissions in the centre. Two hundred and ninety eight (298) patients had ectopic pregnancy accounting for 1.5% of all deliveries and 4.1% of all gynaecological admissions. Most of the affected patients were young nulliparous women. Abdominal pain, amenorrhoea, vaginal bleeding and cervical excitation tenderness were the most common clinical features amongst patients. The ampulla of the fallopian tube was the commonest site of implantation (59.7%) and majority of the cases (70.1%) were already ruptured at the time of presentation. The main mode of treatment was unilateral salpingectomy (76.3%) However, 3.8% of the patients benefited from medical treatment using methotrexate. The case fatality rate was 1.4%. Conclusion: The rate of ectopic pregnancy in the centre is relatively high. Majority of the patients presented late with the ruptured variety. Improvement in health seeking behaviour among our populace coupled with high index of suspicion and use of modern diagnostic techniques by the clinicians will assist in early diagnosis and treatment prior to tubal rupture which will ultimately lead to reduction in maternal morbidity and mortality associated with the condition.
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    Female surgical sterilization at University of Ilorin Teaching Hospital, Ilorin: 10-year review
    (Nigerian Medical Association, Anambra state, 2012) Omokanye, Lukman O.; Salaudeen, A.G; Jimoh, A.A.G.; Panti, Abubakar A.; Saidu, R.; Balogun, O.R
    Background: Given technological advances over the past few decades, female surgical sterilization has become a safe, convenient, easy, and highly effective birth control method for the long term. Objective: This study aims at determining the uptake, indications, timing, surgical technique and complications of voluntary surgical sterilization in Ilorin. Methodology: A retrospective study involving all clients who have undergone female sterilization by mini-laparotomy at the University of Ilorin Teaching Hospital Family Planning Clinic between January 2002 and December 2011. Clinical data were retrieved from the case notes and the information obtained was analyzed with SPSS version 16 of the computer. All the case notes had adequate information for the study, and none was missing. Results: There were 25,418 deliveries with 205 cases of female surgical sterilizations out of which 95 were through mini-laparotomy, giving an incidence of 8% and 3.7 per 1000 deliveries, respectively. The mean age at sterilization was 38.9years. Grand-multiparity and completed family size were the main indications. Seventy-nine percent of the clients had interval procedure and Pomeroy’s method was used among 70.5% of the clients. Local infiltration was used for most (60%) of the clients. Complication attributable to the procedures occurred in 5.3% of the clients. These include, wound sepsis (2.1%), urinary tract infection (1.05%) and one failed sterilization (1.1%). Conclusion: Concerted efforts at female reproductive health education and counseling will help to dispel some of the rumours and misconceptions associated with the procedure.
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    Laboratory Procedure for Evaluating a Patient for Assisted Conception.
    (Delta Reproductive Health Initiative and Research Centre, 2015) Omokanye, Lukman O.; Panti, Abubakar A.
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    Male and Female Challenges of Climacterium and Menopause in Africa
    (Delta Reproductive Health Initiative and Research Centre, 2017) Omokanye, Lukman O.; Panti, Abubakar A.; Tunau, K A.; Olatinwo, Abdulwaheed O.
    Background: The climacteric and menopause is an exceptional period in the life of a woman. It is associated with unique challenges which may affect the quality of life. Recent evidence suggest that there is a similar entity in males the “andropause” which also has its own inherent clinical entities and challenges. There is paucity of the knowledge of the clinical entities and their symptomatology during this period in Africa. Methodology: A Literature search for studies on climacteric, menopause and andropause published between 1995 to 2016 was performed using the google scholar search data base. The bibliographies of included studies were also searched for additional references. About 150 articles were identified and after the elimination of articles unrelated to the subject matter, 42 related articles were available for the review. Result: There are numerous challenges faced by men and women in Africa during the climacteric period and they are accentuated by several intermediating factors which range from ignorance, to cultural taboos and even lack of adequate facilities to cater for their health needs. During this period, the men and woman's age, education, economic status, family structure, health status, social relationships, sexual experiences development style, living conditions and cultural factors impact on individual differences in menopausal adaptation. Conclusion and recommendation: Men and women faces many challenges of menopause and andropause in Africa. This is related to poor knowledge and health seeking behaviour of this group of males and females. Therefore, all tiers of government in collaboration with Non-Governmental Organizations (NGOs) should provide necessary facilities and enabling environments to conduct proper advocacy, counselling, evaluation and treatment of affected individuals.
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    Mayer – Rokitansky Syndrome Type 1 With Karyotype XY Variant: A Case Study
    (College of Health Sciences, University of Ilorin, 2015) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Durowade, K A.; Panti, Abubakar A.; Salaudeen, A.G.; Adewara, E.O.
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    Prevalence of Anaemia at booking in a semi-urban Community in North-Central, Nigeria
    (National Postgraduate Medical College of Nigeria, 2014) Adewara, E,O; Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Durowade, K.A.; Panti, Abubakar A.; Salaudeen, A.G
    Aims and objectives: This study was carried out to determine the prevalence of anaemia at booking clinic, describe the antenatal booking pattern, and categorize the degree of anaemia with certain demographic features. Subjects and methods: This is a descriptive cross-sectional study carried out over a six month period between 1st April and 30th September 2008. A questionnaire was used to obtain demographic information and venous blood samples were collected from 1,086 consecutive patients who consented to participate in the study. The blood samples were tested for haemoglobin levels, genotype and blood group. Results: Seven hundred and thirty two (67.4%) of the women anaemic at booking. Anaemia was more prevalent among multgravidae than primigravidae (p<0.05). Six hundred and sixty nine (61.6%) had mild anaemia while 40(4.4%) had moderate anaemia and 15 (1.4%) were severely anaemic, of which 8 (53.3%) were below 18 years of age. Varied degrees of anaemia were more common among women aged 24-28 years and in the 3rd trimester of pregnancy (80.7%) (p<0.05). One hundred and seventy (15.7%) of the enrolled booked for antenatal care in the 1st trimester, while 703(64.7%) booked in the 2nd trimester and 213 (19.6%) in the 3rd trimester of their pregnancies. Thirteen (1.2%) had sickle cell anaemia. Conclusion: Prevalence of anaemia at booking remains high in our society. Urgent need for public health education on early antenatal booking and improved literacy level of women is suggested to reduce the burden of anaemia in pregnancy.
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    Reproductive Endocrine Aspects of Contraception.
    (Delta Reproductive Health Initiative and Research Centre, 2018) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Panti, Abubakar A.; Balogun, O.R
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    Tubal factor infertility: Hysterosalpingography and Laparoscopic evaluation in Ilorin, Nigeria
    (College of Health Sciences, Delta state University, Abraka, Nigeria, 2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Ibrahim, S.; Saadu, L.; Durowade, K A.; Panti, Abubakar A.
    Objectives: To compare diagnostic accuracy of laparoscopy and HSG in the evaluation of tubal patency among infertile women. Materials and Methods: A cross-sectional prospective study of infertile women who underwent HSG st st and laparoscopy for tubal patency between 1 January 2011 and 31 December 2015. Results: Ninety-seven (97) eligible patients were included in the study. The patients were aged 21-50 years with a mean age of 33 ± 6.6 years. Majority (79.4%) were nulliparous. Most (63.9%) belong to middle social class. Fifty (51.5%) had primary infertility while (48.5%) had secondary infertility. Their duration of infertility ranges from 1-33 years (5.6 ± 5.5). HSG revealed bilateral tubal blockade in 23 (23.7%), bilateral patent tubes in 38 (39.2%) and unilateral patent tube in 36 (37.1%) while laparoscopy showed bilateral tubal blockade in 18 (18.6%), bilateral patent tubes in 51 (52.6%) and unilateral patent tube in 28 (28.8%) respectively. There was significant difference between HSG and laparoscopic findings on tubal status determination (p <0.05). Laparoscopy revealed other tubal and non-tubal pelvic findings not evident on HSG. The sensitivity of HSG was 100%, specificity was 93.7%, and the positive predictive value was 78.3%, with a negative predictive value of 100%. Conclusion: HSG and laparoscopy are of diagnostic importance in the evaluation of tubal status; however, laparoscopy is superior most especially in the detection of other tubal and non tubal pathologies which could be responsible for infertility; thus both tests are complimentary. Tubal Factor Infertility: Hysterosalpingography and Laparoscopic Evaluation in Ilorin, Nigeria.