Browsing by Author "Owolabi, B"

Now showing 1 - 3 of 3
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    Case report of challenges in the management of a rare ductal dependent complex congenital heart disease in a Nigerian tertiary hospital
    (College of Health Sciences, Osun State University, Osun, Nigeria, 2016) Abdulkadir, Mohammed Baba; Olaosebikan, R; Abdulazeez, A; Owolabi, B
    Objective: Complex congenital heart defects are rare and may be difficult to define. They often require early surgery for palliation or correction. A lack of facilities and manpower to provide surgery in developing countries often results in mortality. Case report:A6 month old male infant referred to our unit on account of failure to thrive, cyanosis since birth, easy fatigability and breathlessness. On examination he was small for age with tachycardia and a grade III pansystolic murmur at the left lower sternal edge. Chest radiograph revealed an “egg on side” cardiac appearance with cardiomegaly. Echocardiography confirmed the presence of d-transposition of the great arteries with a patent foramen ovale, large ventricular septal defect and atresia of the proximal main pulmonary artery. The child died while being prepared for referral to a centre for palliative surgery. Conclusion: Transposition of the great arteries with pulmonary atresia is an uncommon congenital heart disease. Early intervention with palliative surgery is necessary to prevent mortality.
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    Relationships between cardiovascular signs and neurological signs in asphyxiated neonates in Ilorin, North Central Nigeria
    (Makarere University Medical School, Kampala, Uganda, 2021) Issa, A; Abdulkadir, Mohammed Baba; Adesiyun, OO; Owolabi, B; SUberu, H; Alabi, K.O; Bakare, R.R.
    Background: Perinatal asphyxia is a condition associated with multiple organ dysfunctions inclusive of cardiovascular dys function. Neurologic predictors of survival have been studied, but little has been reported regarding cardiovascular signs and their role in determining outcome in asphyxia. Objective: The study aimed to determine the relationship between cardiovascular signs and outcomes in asphyxiated new borns with hypoxic ischaemic encephalopathy. Methods: This was a cross sectional study involving asphyxiated new-born babies recruited within the first 24 hours of life. Hypoxic ischaemic encephalopathy staging was done using Sarnat and Sarnat staging. All patients had a detailed cardi ovascular examination on admission, after initial resuscitation (30 – 60 minutes) into admission, and were followed till final outcome: discharge or death. Results: Eighty-five asphyxiated new-borns with HIE were studied over seven months. Abnormal cardiovascular-related signs identified in the patients included respiratory distress (64.7%), small volume pulse (57.6%), hypotension (52.9%), hy poxemia (48.2%) and shock (32.9%). Five babies died. None of the clinical signs had a significant relationship with mortality. Conclusion: Abnormal cardiovascular signs increased with the progression of HIE staging but had no relationship with mortality.
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    Serum brain natriuretic peptide in healthy Nigerian newborn babies
    (Paediatric Association of Nigeria, 2021) Issa, A; Abdulkadir, Mohammed Baba; Adesiyun, O.O.; Owolabi, B; Bello, S.O.; Bakare, R.R.
    Background: Brain natriuretic peptide (BNP) is a sensitive biomarker that is valuable in the management of childhood heart failure. Studies have reported racial differences in the level of BNP, especially in the adult population. The level of BNP in healthy Nigerian newborn babies is unknown. Hence, we determined the level of BNP in healthy term appropriate for gestational age (AGA) newborn babies. Methods: This was a cross- sectional study,85 healthy term AGA newborn babies aged 24 to 72 hours. The babies had relevant demographic parameters docu mented in a proforma and BNP assay analysed using ELISA method. Results: The median IQR serum BNP level was 341.43 (313.39 to 425.45) pg/ml. The median level in females, was higher than males, {393.86 (296.97- 460.62) pg/ml vs328.05 (313.61-389.39) pg/ml, p >0.05}.There was no significant relationship between serum BNP and birth weight, chronological age, gestational age, or mode of delivery (p>0.05 in each case). Conclusion: The study demonstrated high BNP levels in healthy term Nigerian newborns. There was no relationship between BNP, the chronological age, birth weight, gender, gestational age or mode of delivery in babies between 24 to 72 hours of life