Browsing by Author "Omotoso, A.B."
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Item Accuracy of The Clinical Diagnosis of Heart Failure Among General Practitioners in a Resource-Constrained Setting.(World Heart Federation, 2018) OGUNMODEDE, James Ayodele; Kolo, P.M.; Katibi, I.A.; Adekeye, K.A.; Bojuwoye, M.O.; Omotoso, A.B.; Aderibigbe, AAccurate and early diagnosis of Heart failure (HF) is imperative for effective treatment to reduce mortality especially in a resource constrained setting. Very frequently , the first diagnosis and indeed subsequent management of HF is done by general practitioners The objective was to determine the accuracy of the clinical skill of GPS practising in Nigeria in making a correct diagnosis of HF using echocardiography as the gold standardItem Association between blood pressure dipping patterns and hypertension-mediated organ damage among Nigerians with newly diagnosed hypertension.(College of Health Sciences, Osun state University, Osogbo., 2021) Dele-Ojo, B.F; Ogunmodede, James Ayodele; Ojo, O.D; Kolo, P.M.; Katibi, I.A.; Omotoso, A.B.; Adeoye, M.A; Adesokan, Abstract Introduction: Abnormal blood pressure (BP) dipping patterns are associated with increased cardiovascular risk among Africans. This study determined the association between BP dipping patterns and hypertension-mediated organ damage among patients with newly-diagnosed hypertension. Methods: Ambulatory BP monitoring and echocardiography were carried out on 120 participants. Participants were categorized based on the ratio of night-time to day-time systolic BP into 4 patterns: Normal dipper (≥ 10% but < 20%), non-dippers (≥ 0% but < 10%), reverse dippers (<0%) and extreme dippers (≥ 20%). Result: Fifty-one (42.5%) were males, the mean age and body mass index were 44.2±9.8years and 27.1±4.4kg/m2 respectively. The non-dipping pattern was the most prevalent while the reverse dipping had the lowest mitral E/A ratio. Office systolic blood pressure was the only predictor of left ventricular hypertrophy (OR=1.050, 95% CI=1.004-1.098; p-value = 0.034). Conclusions: The non-dipping pattern was the most prevalent abnormal dipping pattern while the reverse dippers had the highest risk of hypertension-mediated organ damage. Office blood pressure was the only predictor of left ventricular hypertrophy. Hence, office BP measurement as well as ambulatory blood pressure measurements are potentially important tools in risk stratification in resource-poor settings of sub-Saharan Africa.Item Benefits, disadvantages and challenges of virtual conferencing in the covid-19 era: adjusting to the new normal.(College of Health Sciences, Osun state University, Osogbo., 2022) Ogunmodede, James Ayodele; Ogunmodede, A.J.; Dele-Ojo, B.F; Omotoso, A.B.; Agede, O.A.; Buhari, O.I.N; Omotoso, A.B.OObjective: The COVID-19 pandemic has had tremendous effect on the medical and scientific community. Measures instituted to curb the spread of the disease such as physical distancing and ban on large gatherings have significantly altered conferencing activities of medical professional associations. With no end in sight to the pandemic, it is certain that medical professional associations may have to make do with purely virtual or hybrid conferencing for some time to come. The objective of this paper is to highlight the benefits, disadvantages and challenges of virtual conferencing Methods: We searched Pubmed, Embase, Scopus, and AJOL databases from January 1, 2021 to December 31, 2021 for publications describing the benefits, disadvantages and challenges of virtual conferencing during the pandemic. This, together with authors' experience formed the resource base for this work. Conclusion: We propose ways the scientific community in Nigeria can maximize the virtual conferencing while the pandemic lasts. We also advocate increased discussion about how to improve the virtual conferencing culture and the development of guidelines for purely virtual or hybrid scientific conferences.Item Public knowledge of heart attack symptoms and prevalence of self-reported cardiovascular risk factors in Ilorin, Nigeria.(Nigerian Cardiac Society, 2015) Kolo, P.M.`; Sanya, E.O.; Bello, H.S.; Gbadamosi, M.S.; Dele-Ojo, B.F; Katibi, I.A.; Omotoso, A.B.; OGUNMODEDE, James AyodeleBackground and objectives: Despite reduction in door‑to‑balloon time in the management of acute myocardial infarction (AMI), prehospital delay by the patients has remained a major concern as benefits derivable from reperfusion treatments are time dependent. This study aimed at evaluating knowledge and perception of warning signs of heart attack among civil servants in Ilorin, Nigeria. Materials and Methods: A pretested structured questionnaire was designed to obtain relevant information on knowledge and perception of heart attack symptoms; and action to be taken if one experiences the condition. Results: Questionnaires from 601 subjects consisting of 312 (51.9%) males and 289 (48.1%) females were analyzed. Although, 78% of the respondents have heard about heart attack, only 44.4% could discriminate a heart attack symptom from other conditions. Higher proportion of women (50.2%) than men (39.1%) could identify a core symptom of heart attack (P < 0.05). Similarly, higher percentage of participants 40 years and older (48.3%) were more knowledgeable than those younger than 40 years (42.9%), but the difference was not statistically significant (P > 0.05). Higher percentage of women reported prior cardiovascular disease/risk factors than men. Conclusion: We concluded that participants have low knowledge of heart attack symptoms with women being more knowledgeable than their male counterparts. There is the need for community education on heart attack warning signs and the need for early hospital presentation by affected individuals.Item Rehospitalization rate and predictors of rehospitalization in heart failure patients in north central Nigeria(College of Health Sciences, University of Ilorin, Nigeria, 2022) Ogunmodede, James Ayodele; Kolo, P.M.; Dele-Ojo, B.F; Yusuf, I.A.; Salau, I.L.; Katibi, I.A.; Omotoso, A.B.INTRODUCTION Heart failure (HF) is a major cause of morbidity and mortality worldwide. It imposes considerable strain on patients through the burden of recurrent rehospitalizations.. OBJECTIVES The objective of the study was to determine the rehospitalization rate of heart failure patients managed over a 3-year period in our Centre, identify factors predictive of rehospitalization and determine the survival curve for 6-month among our patients. METHODS A retrospective cohort study of patients with HF managed in our Hospital between 2014 and 2017. RESULTS 148 patients who had complete data were studied. 25.7% of patients were rehospitalized at least once during the study period. 16.2% were rehospitalised by 6 months. Only age was found to be predictive of 6-month rehospitalization OR 1.03, (CI 1.004-1.056), p=0.024 suggesting that every one year increase in age is predictive of a three percent increase in likelihood of rehospitalisation. The Kaplan-Meier survival curve for 6-month rehospitalization among rehospitalized patients is shown below. CONCLUSION The rehospitalization rates among our patients are slightly higher among other reported rates in our environment. In the resource-constrained setting we practice issues of treatment affordability and availability of novel medications and treatment strategies are important considerations to reduce rehospitalization in HFpatients.Item Sex-related differences in clinical, electrocardiographic, and echocardiographic indices among normotensive offspring of black parents with hypertension.(Faculty of Medicine, Ahmadu Bello University, Zaria, Nigeria, 2017) Kolo, P.M.; Sanya, E.O.; Omotoso, A.B.; Soladoye, A.O; Ogunmodede, James AyodeleContext: Blood pressure tracking has suggested that the difference in blood pressure between women and men begins to manifest during the adolescent period. It is therefore postulated that sex-related cardiac structural and functional differences that could predict future events may exist in the heart of offspring of parents with hypertension. Aims: This study aimed at evaluating the effects of sex difference on the heart of offspring of parents with hypertension. Settings and Design: Cross-sectional study. Participants and Methods: A group of offspring of parents with hypertension aged between 15 and 25 years were recruited for the study if they had normal blood pressure and gave consent. They had clinical, electrocardiography, and echocardiographic assessments. Results: Sixty-five participants consisting of 47 males and 18 females participated in the study. Mean systolic blood pressure was higher (P = 0.001) in the males compared with the females but the diastolic blood pressure was similar between them. Electrocardiogram (ECG) parameters (heart rate, QRS axis and QTc) were similar between the males and the females but the summation of ECG voltage (SV2 + RV6) was higher in the former than the latter. Left ventricular (LV) posterior wall (P = 0.001), aortic root diameter (P = 0.014), LV mass (P = 0.001), LV mass index (P = 0.001), and relative wall thickness (P = 0.003) were higher in the male compared with the female participants, respectively. However, more females (72.2%) had normal LV geometry compared with the males, P = 0.03. Conclusion: There are subtle clinical, electrocardiographic, and echocardiographic differences between the heart of male and female offspring of parents with hypertension with the former having more precursors of future cardiovascular events.Item Structural echocardiographic abnormalities seen in HIV/AIDS patients are independent of CD4 count.(Medical and Dental Consultants Association of Nigeria., 2017) Ogunmodede, James Ayodele; Kolo, P.M.; Katibi, I.A.; Salami, A.K.; Omotoso, A.B.Introduction: The human immunodeficiency virus (HIV) infection remains one of the most daunting public health challenges today. Cardiac involvement in HIV/acquired immune deficiency syndrome (AIDS) is frequent and has been recognized on autopsy since the emergence of the pandemic. The objective of the study was to assess the pattern of structural echocardiographic (echo) findings in HIV/AIDS patients and compare this to the echo findings in apparently healthy HIV‑negative controls. Materials and Methods: One hundred and fifty HIV‑ positive patients were recruited consecutively from the HIV patients attending the University of Ilorin Teaching Hospital, Ilorin, North Central, Nigeria. One hundred and fifty age‑ and sex‑matched controls were also recruited from the surrounding community. All the individuals had clinical examination, electrocardiography (ECG) and echocardiography (echo) done. Results: ECG abnormalities were seen in 55.3% of the HIV‑positive patients compared with 2.7% of controls (P < 0.001). The overall prevalence of echo abnormalities among the patients was 54%, against 15.3% (P < 0.001) of the controls. All the structural dimensions of the cardiac chambers were significantly greater than the cardiac chamber dimensions in the controls except for left atrial dimension (LAD). When the patients were considered in two groups of those with CD4 count less than 200 cells/mm 3 than those with CD4 count more than 200 cells/mm 3 , the structural chamber dimensions were similar between both groups. Conclusions: Echo is an important tool for detecting cardiac abnormalities in HIV/AIDS patients. There is a high prevalence of echo abnormalities among HIV patients seen in our centre. The HIV infection was associated with increased structural dimensions of cardiac chambers compared with HIV‑negative controls. This however did not seem to be related to disease severity as the chamber dimensions were similar between those with CD4 count below and above 200 cells/mm 3 .