Association between blood pressure dipping patterns and hypertension-mediated organ damage among Nigerians with newly diagnosed hypertension.
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Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
College of Health Sciences, Osun state University, Osogbo.
Abstract
bstract
Introduction: Abnormal blood pressure (BP) dipping patterns are associated with increased
cardiovascular risk among Africans. This study determined the association between BP dipping patterns
and hypertension-mediated organ damage among patients with newly-diagnosed hypertension.
Methods: Ambulatory BP monitoring and echocardiography were carried out on 120 participants.
Participants were categorized based on the ratio of night-time to day-time systolic BP into 4 patterns:
Normal dipper (≥ 10% but < 20%), non-dippers (≥ 0% but < 10%), reverse dippers (<0%) and extreme
dippers (≥ 20%).
Result: Fifty-one (42.5%) were males, the mean age and body mass index were 44.2±9.8years and
27.1±4.4kg/m2 respectively. The non-dipping pattern was the most prevalent while the reverse dipping
had the lowest mitral E/A ratio. Office systolic blood pressure was the only predictor of left ventricular
hypertrophy (OR=1.050, 95% CI=1.004-1.098; p-value = 0.034).
Conclusions: The non-dipping pattern was the most prevalent abnormal dipping pattern while the reverse
dippers had the highest risk of hypertension-mediated organ damage. Office blood pressure was the only
predictor of left ventricular hypertrophy. Hence, office BP measurement as well as ambulatory blood
pressure measurements are potentially important tools in risk stratification in resource-poor settings of
sub-Saharan Africa.
Description
Keywords
Dipping patterns, hypertension-mediated organ damage, echocardiography, left ventricular hypertrophy, Nigeria.
Citation
Research Journal of Health Sciences 9(3): 197-206