Browsing by Author "Ogunmodede, A.J."
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Item Acute Rapid QTc Changes Following Chloroquine Overdose with No Suicidal Intent(The Biomedical Communications Consult, 2020) Ogunmodede, James Ayodele; Ogunmodede, A.J.; Dele-Ojo, B.F; Buhari, O.I.NWe report a 39 year-old male with unintentional chloroquine overdose without any suicidal intention. Marked QTc prolongation of 0.508sec was observed acutely though patient’s total ingested dose was lower than most fatal doses reported in literature. This range of QTc carries a predisposition to potentially fatal ventricular arrhythmias. Serial electrocardiograms (ECGs) demonstrated gradual return of QTc towards normal while patient was on observation without any indication for active intervention. We recommend that in the event of chloroquine overdose, close monitoring of the cardiovascular system should be done even in apparently stable individuals.Item Benefits, disadvantages and challenges of virtual conferencing in the covid-19 era: adjusting to the new normal.(College of Health Sciences, Osun state University, Osogbo., 2022) Ogunmodede, James Ayodele; Ogunmodede, A.J.; Dele-Ojo, B.F; Omotoso, A.B.; Agede, O.A.; Buhari, O.I.N; Omotoso, A.B.OObjective: The COVID-19 pandemic has had tremendous effect on the medical and scientific community. Measures instituted to curb the spread of the disease such as physical distancing and ban on large gatherings have significantly altered conferencing activities of medical professional associations. With no end in sight to the pandemic, it is certain that medical professional associations may have to make do with purely virtual or hybrid conferencing for some time to come. The objective of this paper is to highlight the benefits, disadvantages and challenges of virtual conferencing Methods: We searched Pubmed, Embase, Scopus, and AJOL databases from January 1, 2021 to December 31, 2021 for publications describing the benefits, disadvantages and challenges of virtual conferencing during the pandemic. This, together with authors' experience formed the resource base for this work. Conclusion: We propose ways the scientific community in Nigeria can maximize the virtual conferencing while the pandemic lasts. We also advocate increased discussion about how to improve the virtual conferencing culture and the development of guidelines for purely virtual or hybrid scientific conferences.Item Characteristics of patients with acute heart failure in North Central Nigeria.(College of Health Sciences, Osun state University, Osogbo., 2021) Ogunmodede, James Ayodele; Kolo, P.M.; Bojuwoye, M.O.; Dele-Ojo, B.F; Ogunmodede, A.J.; Kolo, P,M., Omotoso, A.B.O.Objectives: Heart failure (HF) is an important cause of hospital admission in Nigeria. HF is increasingly prevalent because the population is aging and HF epidemiology is changing. We aimed at profiling the socio-demographic, clinical and echocardiographic (Echo) characteristics of patients admitted for acute HF. This is one of the largest cohorts of HF patients profiled in Nigeria so far. Methods: Cross sectional design. Socio-demographic, clinical and Echo data were collected from 455 patients admitted for AHF at University of Ilorin Teaching Hospital, North central, Nigeria. Results: Mean age of patients was 58.9± 15.7years, (men were older than women, P= 0.006). 265(58.2%) were males, most patients were aged >60 years, 4.8% had pre-existing Type2 Diabetes mellitus. 53.2% of patients presented in New York Heart Association StagesIII and IV. Median duration of admission was 11days (IQR, 6-17), intrahospital mortality- 11.6%. Hypertension was the commonest aetiological factor (62.4%), followed by dilated cardiomyopathy 17.6%, rheumatic heart disease (6.6%), Peripartum cardiomyopathy (5.3%), and others. Conclusion: AHF patients in our study are older than those in previous studies in Nigeria and sub-Saharan Africa. Hypertension is main driver of AHF, and patients largely present with clinically advanced disease necessitating stronger public health education about risk factors and early presentation.Item COVID-19 related disruption of out-patient services: an opportunity for integrating telemedicine into clinical practice in public hospitals in Nigeria.(The Biomedical Communications Consult, 2020) Ogunmodede, James Ayodele; Ogunmodede, A.J.; OYELEKE, O.A.; Bolarinwa, O.A.; Buhari, O.I.N; Kolo, P.M.; Olokoba, A.B.In December 2019, the first cases of a viral pneumonia were reported in Wuhan, Hubei Province, China. Deep thoroughput sequencing of airway secretions of the patients revealed a novel coronavirus named severe acute respiratory syndrome SARS-CoV-2. On February 11, 2020 the World Health Organization (WHO) named the disease Coronavirus disease- 2019 (COVID-19) and declared it a global pandemic on March 11, 2020. As the COVID-19 cases escalated, it became a source of tremendous disruption of the lives and means of livelihood of huge populations of people worldwide. The pandemic continues to spread and the number of cases of COVID-19 worldwide numbered a cumulative 22,034,395 with 776,801 deaths as at August 17, 2020. (Worldometer COVID-19 Pandemic, 2020) Nigeria had recorded 49, 485 cases and 977 deaths by the said date while South Africa leads the continent’s tally of the disease with 589,886 cases and 11,982 deaths – the fifth highest in the world. (Worldometer COVID-19 Pandemic, 2020). The implementation of measures instituted to limit the spread of the disease by most national governments included wearing of face masks in public and restriction of human movement and physical interaction.Item Indirect victims of COVID-19: Effect of closure of the Medical Outpatient services on Non-COVID-19 patients(West African College Of Physicians, 2021) Ogunmodede, James Ayodele; Ogunmodede, A.J.; Bojuwoye, M.O.; Bello, A.H.; Buhari, O.I.N; Kolo, P.M.Background: In order to reduce COVID-19 transmission and protect healthcare workers, the outpatient departments (OPDs) in many hospitals worldwide were closed down in the early days of the pandemic. Patients being managed for chronic medical illnesses who subsequently suffered reduced access to healthcare have been described as “the patients left behind”. The study aimed at assessing the impact of the closure of the Medical OPD of the University of Ilorin Teaching Hospital (UITH) during the government-declared lockdown between March 23, 2020 and June 8, 2020 on the health and perceived well-being of patients with chronic medical illnesses. Methods: A cross-sectional study of 166 patients with chronic medical illnesses attending the MOPD in UITH. Results: Mean age of participants was 49.5±18.5 years, 82 (49.4%) were male, median duration of attending MOPD was 24months (IQR 12-36). 84 patients(50.6%) perceived a negative affectation of their well-being by the closure of MOPD. Being >50years was associated with a perception of negative affectation of well-being (P=0.02). 130 patients (78.2%) had clinic appointments that fell within the period under review. 61(69.3%) of the 88 patients who had medical complaints during the period could not reach a doctor and this was associated with a perception of negative affectation of their well being. The commonest action they took was to do nothing (27.9%), two (3.3%) resorted to herbal concoctions. 49 (29.9%) felt their complaints were urgent. Conclusions: Our study identifies that patients with chronic medical illness are potential victims of COVID-19 related disruption of healthcare services. Healthcare managers in Nigeria must develop alternatives such as telemedicine that sustain face-to-face medical interaction during eventualities.Item The Indirect victims of COVID-19: perception of non- COVID-19 patients about the effect of closure of the medical outpatient services on their health.(West African College Of Physicians, 2022) Ogunmodede, James Ayodele; Ogunmodede, A.J.; Dele-Ojo, B.F; Bello, A.H.; Bolarinwa, O.A.; Bojuwoye, M.O.; Yusuf, I.A.; Abiola, T.S; Olokoba, A.B.; Kolo, P.M.BACKGROUND: In order to reduce COVID-19 transmission and protect healthcare workers, the outpatient departments (OPDs) in many hospitals worldwide were closed down in the early days of the pandemic. Patients being managed for chronic medical illnesses who subsequently suffered reduced access to healthcare have been described as “the patients left behind”. AIM: The study aimed at assessing the impact of the closure of the Medical OPD in University of Ilorin Teaching Hospital (UITH) on the health and perceived well-being of patients with chronic medical illnesses. METHODS: A cross-sectional study of 180 patients with chronic medical illnesses attending the MOPD in UITH. RESULTS: Mean age of participants was 50.2±18.2years, 92 (51.1%) were male, median duration of attending MOPD was 21 months (IQR 12-36). 92 patients (51.1%) perceived a negative affectation of their well-being by the closure of MOPD. Being >50 years was associated with a perception of negative affectation of well-being (P=0.042). 140 patients (77.8%) had clinic appointments that fell within the period under review. 67(69.3%) of the 97 patients who had medical complaints during the period could not reach a doctor and this was associated with a perception of negative affectation of their wellbeing. The commonest action they took was to do nothing (28.3%), three (4.5%) resorted to herbal concoctions. 19 (29.9%) felt their complaints were urgent. CONCLUSION: Our study identifies that patients with chronic medical illness are potential victims of COVID-19 related disruption of healthcare services. Healthcare managers in Nigeria must develop alternatives such as telemedicine that sustain face-to-face medical interaction during eventualities.Item Prevalence and predictors of problematic smartphone use among university undergraduates.(Community Health Society of Malaysia., 2023) Ogunmodede, James Ayodele; Ogunmodede, A.J.; Ahmed, A; Buhari, O.I.N; Agede, O.A.; Bolarinwa, O.A.; Omotoso, A.B.OBackground: A smartphone is a mobile phone that performs many of the functions of a computer, typically having a touchscreen interface, internet access, and an operating system capable of running downloaded applications. The objectives of this study were to determine the prevalence and predictors of problematic smartphone use (PSU) among university undergraduates. Materials and Methods: Cross-sectional design. PSU was studied among the students using the Smartphone Addiction Scale- Short version (SAS-SV). Results: Mean age was 21.3+2.59 years, mostly female (55.2%). The prevalence of smartphone ownership was 99.4% (3305). 13.9% of students had PSU. Factors associated with PSU were female gender (p=0.001), owning more than one smartphone (p=0.001), time spent on making phone calls (<0.001), surfing social media (<0.001), engaging in overnight phone call/social media chat (p=0.001), use of Twitter (p=0.002), Instagram (p=0.001), Snapchat (p=0.001), YouTube (p=0.001), online gaming (p=0.002), presence of probable psychiatric morbidity (p=0.001) and insomnia (p<0.001). The predictors of PSU were female gender (OR 1.305, p=0.038), engaging in overnight calls or social media chats (OR 2.243, p=0.001), using a smartphone in bed when unable to sleep at night (OR 2.832, p=0.003), probable psychiatric morbidity (OR 1.671, p<0.001), and insomnia (OR 1.298, p=0.043). Conclusion: Compared with other studies the prevalence of PSU among our participants is relatively low. However, PSU is a potentially disruptive behavioural addiction in undergraduates. Knowing predictors of PSU offers an opportunity for preventive counselling early in the course of study of all undergraduates.Item Problematic smartphone use and addiction among University Undergraduates in Ilorin, Nigeria - A pilot study.(West African College Of Physicians, 2021) Ogunmodede, James Ayodele; Ogunmodede, A.J.; Bello, A.H.; Buhari, OBackground: Smartphone use has increased at an increased pace across all age and socio-economic strata of the society worldwide. Smartphone addiction is an emerging but understudied public health issue. Little is known about its epidemiology, especially among young people. Teenagers and young people are an important target market for smartphones hence for university undergraduates, who mostly fall into this category, smartphone use is a big issue both from academic, social, psychological and behavioural standpoints. The phone is useful as an indispensable learning aid, but smartphones have also become a focal object influencing social, psychological and behavioural aspects of the lives of students. Methods: 242 undergraduate students of the University of Ilorin were selected by systematic random sampling in a pilot study and asked to fill a socio-demographic questionnaire and the Smartphone Addiction Scale-Short Version (SAS-SV). Results: The mean age of participants was 21.28+2.14years, 96.7% of the respondents owned a smartphone and 95.5% admitted accessing social media on their phones. Using normative SAS-SV score cut-offs of 31 in males and 33 in females, 29.1% of the students were addicted to their smartphones, 32.1% of males and 28% in females. The mean SAS-SV score was 28.52+9.86. The smartphone addiction score correlated positively with the number of hours spent on the phone daily, the age of the students correlated negatively with the number of hours spent on the phone daily. Smartphone addiction was not associated with gender, students' academic performance Cumulative Grade Point Average or level of study. Conclusions: Smartphone addiction is an important problem among university undergraduates. Younger students are more likely to spend longer hours on their phone, and have increased likelihood of addiction. It is important to introduce behavioural modification measures early into the school curriculum to prevent potential hazards to students in the course of their study.Item Relationship Between CD4 Count, Neutrophil-To-Lymphocyte Ratio, Platelet-To-Lymphocyte Ratio and Left Ventricular Systolic Function in HIV/AIDS Patients(Kenyan Medical Association., 2023) OGUNMODEDE, James Ayodele; Agede, O.A.; Dele-Ojo, B.F; Adeoye, O.G.; Ogunmodede, A.J.; Omotoso, A.B.OBackground: Inflammation is a cardinal feature of Human Immunodeficiency Virus (HIV) infection and accounts for most of its clinical manifestations. Cardiovascular involvement is common in HIV. Haematologic inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are elevated in some cardiovascular diseases in the non-HIV population. CD4 count correlates with left ventricular size. The relationship between haematologic inflammatory markers NLR and PLR and left ventricular (LV) systolic function and their prognostic value is not well studied in HIV patients. Objective: To determine the relationship between CD4 count, NLR and PLR and LV ejection fraction (EF) and their diagnostic value as surrogates for the occurrence of LV systolic dysfunction (LVSD) Design: Cross-sectional Setting: The Cardiology unit of the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria Participants: 150 HIV positive patients Outcome measures: The relationship between CD4 count, NLR and PLR and LV ejection fraction (EF) and their diagnostic value for the occurrence of LV systolic dysfunction (LVSD) esults: The mean age was 37.14+8.6 years, 86 (64%) female, median duration of illness 6(0.94-24) months. NLR and PLR had a negative correlation with LV EF, the CD4 count had positive correlation. On multivariate analysis only PLR was predictive of EF. A cut-off PLR of 169.5 was only weakly discriminatory of LVSD with sensitivity of 81.3% and specificity of 72.9%, AUC 0.794. Conclusion: CD4 count, and inflammatory markers correlate with LVEF in HIV patients. Only PLR was predictive, its value as a diagnostic surrogate for LVSD needs further investigation.