Acute Rapid QTc Changes Following Chloroquine Overdose with No Suicidal Intent
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Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
The Biomedical Communications Consult
Abstract
We report a 39 year-old male with unintentional chloroquine overdose without any suicidal intention. Marked QTc prolongation
of 0.508sec was observed acutely though patient’s total ingested dose was lower than most fatal doses reported in literature. This
range of QTc carries a predisposition to potentially fatal ventricular arrhythmias. Serial electrocardiograms (ECGs) demonstrated
gradual return of QTc towards normal while patient was on observation without any indication for active intervention. We
recommend that in the event of chloroquine overdose, close monitoring of the cardiovascular system should be done even in
apparently stable individuals.
Description
Keywords
Chloroquine. Acute QTc changes, overdose, suicidal intent
Citation
African Journal of Biomedical Research 23(2);297-300