Browsing by Author "Odebisi-Omokanye, M.B."
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Item Analysis of Indoor Air Microflora of Some Daycare Centres in Ilorin South Local Government Area, Nigeria(Faculty of Natural Sciences, Al-Hikmah University, Ilorin, Nigeria, 2017) Sule, I.O.; Agbabiaka, T.O.; Odebisi-Omokanye, M.B.; Zakariyah, R.F.; Ali, A.A.Item Antibacterial Efficacy of Aqueous and Ethanolic Extracts of Hibiscus sabdariffa(Centrepoint Journal (Science Edition), 2020) Agbabiaka, T.O.; Sule, I.O.; Uthman, L.; Odebisi-Omokanye, M.B.Item Antibacterial evaluation of extract of seed of kernel and leaf of Moringa oleifera against bacteria from raw cow milk(Nigerian Journal of Microbiology, 2016) Zakariyah, R.F; Sani, A; Odebisi-Omokanye, M.B.; Ahmed, R.N.Abstract: Moringa oleiferahas been found very useful in a lot of health related problems owing to its medicinal components and values, these has led to research on its antibacterial activity against food borne pathogens. Aqueous and acetone extracts of Moringa oleifera seed kernel and leaf were evaluated for antibacterial activity against Bacillus cereus, Staphylococcus aureus and Escherichia coli isolated from raw cow milk. The antibacterial assay was carried out at concentrations of 250, 125, 62.5 and 31.25mg/ml using modified agar well diffusion method. Aqueous extract inhibited the growth of test isolates at varying degrees. Aqueous extract of seed kernel was highly inhibitory on Staphylococcus aureus with a zone of inhibition (23.33±1.20mm) at concentration of 250mg/ml. Minimum Inhibitory Concentration showed that both extracts inhibited the growth of Bacillus cereus, Staphylococcus aureus and Escherichia coli at concentrations ranging from 125 to 21.25mg/ml. The antibacterial effect of standard antibiotics was performed and it was observed that Gentamycin inhibited growth of the three test isolates. Preliminary phytochemical screening revealed the presence of alkaloids, flavonoids, steroids, saponin, tannin, phenols, glycosides and carbohydrates compound in the extracts. From the present study, Moringa oleifera seed kernel and leaf can be a promising source of phytochemical components and further studies is therefore recommended. Key words: Food-borne pathogens, Minimum Inhibitory Concentration, Moringa oleifera, Phytochemical screening,Item Basic Laboratory Practicals in Microbiology(Department of Microbiology, University of Ilorin., 2017) Olayemi, A.B.; Sani, A.; Oyeyiola, G.P.; Omojasola, P.F.; Kolawole, O.M.; Arekemase, M.O.; Ahmed, R.N.; Saliu, B.K.; Anibijuwon, I.I.; Sule, I.O.; Agbabiaka, T.O.; Adebisi, O.O.; Udeze, A.O.; Ahmed El-Imam, A.M.; Oke, M.A.; Kazeem, M.O.; Ajijolakewu, A.K.; Odebisi-Omokanye, M.B.; Laba, S.A.; Adetitun, D.O.; Gambari-Ambali, R.O.; Zakariyah, R.F.; Abioye, J.A.; Adam, A.I.; Olabanji, S.O.Item Basic Laboratory Practicals in Microbiology(Department of Microbiology, University of Ilorin, Nigeria, 2017) Olayemi, A.B.; Oyeyiola, G.P.; Omojasola, P.F.; Ahmed, R.N.; Saliu, B.K.; Anibijuwon, I.I.; Sule, I.O.; Agbabiaka, T.O.; Adebisi, O.O.; Udeze, A.O.; El-Imam, A.M.; Oke, M.O.; Kazeem, M.O.; Ajijolakewu, A.K.; Odebisi-Omokanye, M.B.; Laba, S.L.; Adetitun, D.O.; Gambari-Ambali, R.O.; Zakariyah, R.F.; Abioye, J.A.; Adam, A.I.; Olabanji, S.O.Item Effects of 'Disinfectant A' on the Physicochemical and Bacteriological Quality of Some Well Water(Journal of Science, Technology, Mathematics and Education, 2016) Sule, I.O.; Odebisi-Omokanye, M.B.; Gambari-Ambali, R.O.; Okewale, T.A.Item High seroprevalence of Cytomegalovirus infection among pregnant women in Ilorin, Kwara State, Nigeria(Faculty of Physical Sciences, University of Ilorin. Ilorin, Nigeria, 2017) Odebisi-Omokanye, M.B.; Udeze, A.O.; AbdulRaheem, A.A.; AbdulRazaq, N.E.; Afolabi, L.M.; Yusuf, A.A.Cytomegalovirus (CMV) is an important public health problem worldwide and has been shown to be an important aetiological agent of intrauterine infection in pregnant women that results into congenital malformations such as cerebral palsy, blindness and sensor neural loss. This study was conducted to determine the seroprevalence of human cytomegalovirus among pregnant women in Kwara State. Two hundred and twenty five (255) blood samples were collected from pregnant women attending antenatal clinics in two selected state Hospitals in Kwara State. Serum obtained from the blood samples were examined for the presence of CMV IgM and IgG antibodies by ELISA method. Out of the 225 pregnant women tested, 221 (98.2%) and 56 (24.9%) were CMV IgG and IgM positive, respectively. A significant statistical relation was observed between CMV IgG seropositivity and gestational age, occupation and marriage type, while the age, parity and gestational age were significantly associated with CMV IgM seropositivity. This extremely high level of CMV infection among these pregnant women as observed in this study indicates that the virus is prevalent in the study area. It is therefore imperative to implement a routine CMV infection screening in pregnant women within the State and also need for vaccination in order to prevent birthing of children with avoidable birth defectsItem Laboratory Practicals in Microbiology(Department of Microbiology, University of Ilorin, Nigeria, 2018) Olayemi, A.B.; Sani, A.; Oyeyiola, G.P.; Omojasola, P.F.; Kolawole, O.M.; Ahmed, R.N.; Saliu, B.K.; Anibijuwon, I.I.; Sule, I.O.; Agbabiaka, T.O.; Adebisi, O.O.; Udeze, A.O.; El-Imam, A.M.; Oke, M.O.; Kazeem, M.O.; Ajijolakewu, A.K.; Odebisi-Omokanye, M.B.; Laba, S.L.; Adetitun, D.O.; Gambari-Ambali, R.O.; Zakariyah, R.F.; Abioye, J.A.; Adam, A.I.; Olabanji, S.O.Item Microbiological Assessment of Laboratory Workbench Surfaces(FACULTY OF PHYSICAL SCIENCES, UNIVERSITY OF ILORIN., 2018) Sule, I.O.; Odebisi-Omokanye, M.B.; Agbabiaka, T.O.; Saliu, B.K.; Ahmed, R.N.; Adewumi, O.S.; Afolabi, A.A.Item Microbiological Assessment of Laboratory Workbench Surfaces(Faculty of Physical Sciences, University of Ilorin., 2018) Sule, I.O.; Odebisi-Omokanye, M.B.; Agbabiaka, T.O.; Saliu, B.K.; Ahmed, R.N.; Adewumi, O.S.; Afolabi, A.A.Item Prevalence of enteric Adenovirus among diarrheic children less than five years in Children’s Specialist Hospital, Ilorin, Kwara State, Nigeria(Society for Experimental Biology of Nigeria, 2022) Odebisi-Omokanye, M.B.; Udeze, A.O.; Akinfaye, O.D.; Agbaje, S.T.Acute infective gastroenteritis is a major global health problem with children under 5 years of age being predominantly susceptible. Adenoviruses, mainly enteric adenoviruses (EAds) type 40 (Ad40) and type 41(Ad41), have been implicated in causing acute and severe diarrhea in young children worldwide. This study was therefore conducted to elucidate the prevalence and epidemiological features of enteric adenovirus in children aged 0-5 years being managed for acute diarrhea in Children’s Specialist Hospital Ilorin, Kwara State, Nigeria where there is little or no information on its prevalence. A total of one hundred and eighty-eight diarrheic stool samples were obtained and screened for the presence of adenoviruses using monoclonal antibody-based Enzyme Immuno Assay (EIA), (Cortez Diagnostics INC., USA). The results were statistically analysed (Chi-Square and P-value) using descriptive Cross Tab Pearson’s Statistical Method. Adenovirus antigen was detected in 23.4% (44/188) of the diarrheic stool samples. Among the infected patients, children < 2 years old were more vulnerable to enteric adenovirus infection, with the peak infection occurring between 7-12 months of age (28.2% prevalence rate). Also, male children had a higher incidence rate of 13.8% while the female had an incident rate of 9.6%. There was a significant association between marital status (p=0.04) and occupation (p=0.02) of the parent or guardian of the children and adenovirus infection. The findings from this study suggest that adenoviruses are important etiologic agents of diarrhoea in children within Ilorin Metropolis, thusthere is an urgent need for proper diagnosis of adenovirus among children with symptoms of diarrhoea.Item Screening of Prosopis africana for Antimicrobial Activity Against Selected Oral Pathogens(Faculty of Physical Sciences and Faculty of Life Sciences, University of Ilorin., 2017) Zakariyah, R.F.; Sani, A.; Odebisi-Omokanye, M.B.; Akolade, J.O.; Ahmed, R.N.; Jimoh, F.A.; Badmus, S.A.Item Serosurvey of Herpes simplex virus type-2 infection among HIV infected individuals accessing a secondary health care facility in Kwara State, North Central Nigeria.(Faculties of Life and Physical Sciences, University of Ilorin, 2017) Odebisi-Omokanye, M.B.; Udeze, A.O.; Akanbi, K.; Jimoh, N.K.; Imam, M.A.Herpes Simplex Virus type 2 (HSV-2) is a commonly opportunistic infection among HIV seropositive subjects and acts synergistically with HIV to accelerate disease progression. This is across sectional, Hospital-based study designed to determine the prevalence of HSV-2 IgM and IgG antibodies among HIV-1infected individuals accessing the HAART Clinic of General Hospital Offa, Kwara State Nigeria. Blood samples were collected from consenting 276 (age range 11-70; mean age of 36.8 years) HIV-1 infected individuals after collecting pertinent socio-demographic data using questionnaires. The blood was separated into plasma and packed cells. The former was tested for the presence of anti- HSV-2 IgM and IgG using ELISA test kits from Diagnostic Automation INC., USA. Data were analyzed using Chi square test with SPSS version 21 software and the level of significance was determined to be P < 0.05.Out of 276 samples tested, 116 (42.0%) and 39 (14.1%) were respectively positive for HSV-2 IgG and IgM antibodies. These respectively represent latent and active HSV-2 infections. Gender, occupation and clinical state of the subjects were the main correlates of IgM serpositivity while gender, occupation, marital status and CD4+ count correlates with IgG seropositivity. The prevalence of anti-HSV-2 IgM and IgG antibodies in this cohort of HIV-infected individuals is high. There is therefore the need for routine test for HSV-2 infection among HIV infected individuals to determine the extent of infection and proper management especially the active infections