Browsing by Author "Ige, O.A."

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    Clomiphene Resistant Polycystic Ovarian Syndrome: Analysis of Outcomes following Laparoscopic Ovarian Drilling in Infertile Women in Ilorin, North-Central, Nigeria.
    (African Health Research Organization, 2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Panti, Abubakar A.; Ibrahim, S.; Oyedepo, O.O.; Ige, O.A.; Adegboye, M.B.
    Background: Laparoscopic ovarian drilling (LOD) is one‑off treatment modality for clomiphene citrate (CC)‑resistant polycystic ovarian syndrome (PCOS) avoiding the need of medical therapy and its attendant complications. Aims and Objectives: This study aimed at determining the efficacy of LOD in women with anovulatory infertility secondary to CC‑resistant PCOS and factors influencing reproductive outcomes. Materials and Methods: A cross‑sectional study of infertile women who underwent LOD on account of CC‑resistant PCOS between January 2012 and December 2015 at a tertiary institution. Results: Patients aged 24–38 years (29.7 ± 3.6 years) and their body mass index (BMI) ranges from 20 to 35 (26.3 ± 4.3). The majority (90.5%) were nulliparous. Most (61.3%) had primary infertility. Their duration of infertility ranges from 1 to 13 years (4.3 ± 2.7) and ovarian volume ranges from 10 to 24 cm3 (mean, right ovary = 15.2 ± 3.2; left ovary = 16.3 ± 3.2). The number of drills per ovary ranged from 4 to 14 (mean, right ovary = 7.4 ± 2.1; left ovary = 7.3 ± 2.1) and the luteinizing hormone/follicle stimulating hormone (LH)/FSH ratio ranges from 2 to 6 (3.2 ± 1.4). All achieved spontaneous resumption of menses and ovulation with mean durations of 4.0 ± 1.8 days and 5.3 ± 3.2 weeks, respectively. Eighty‑three (60.6%) clinical pregnancies were recorded, of which 68 (49.6%) resulted to live births (61 singletons and 7 twin births) and 14 (10.2%) early first trimester miscarriages. The mean time interval from LOD to pregnancy was 4.4 ± 1.1 months. There was a significant association between BMI, duration of infertility, FSH/LH ratio, and pregnancy outcomes (P < 0.05). Conclusion: LOD is the most preferred treatment modality for CC‑resistant PCOS as it resulted in higher pregnancy rate.
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    Comparative study of Haemodynamic Effects of Intravenous Ketamine-Fentanyl and Propofol-Fentanyl for Laryngeal Mask Airway Insertions in children undergoing Herniotomy under General Anaesthesia in a Nigerian Tertiary Hospital
    (National Postgraduate Medical College of Nigeria., 2022) Okeyemi, A; Suleiman, Z.A; Oyedepo, O.O; Bolaji, B.O.; Adegboye, M.B; Ige, O.A.
    Background: Insertion of laryngeal mask airway (LMA) with propofol in children may cause hypotension, laryngospasm and apnoea. Ketamine and fentanyl have been combined separately with propofol to prevent depression of cardiovascular system during LMA insertion, especially in paediatric patients. Ketamine-fentanyl and propofol-fentanyl combinations have analgesic effect, prevent coughing and apnoea and regarded as agents of choice for LMA insertions. However, the cardiovascular effects of the two admixtures for LMA insertions have not been fully assessed in children. We compared the haemodynamic effects of ketamine-fentanyl and propofol-fentanyl combinations for LMA insertion in paediatric patients who underwent herniotomy in our facility. Patients and Methods: This comparative study was conducted on 80 children aged 1–15 years, ASA physical Statuses I and II, who had herniotomy under general anaesthesia. The patients were randomised into two groups (A and B) of 40 patients each and LMA was inserted following administrations of the two different drug combinations. Patients in Group A received pre-mixed ketamine 2 mg/kg and fentanyl 2 μg/kg while the patients in Group B received pre-mixed propofol 2.5 mg/ kg and fentanyl 2 μg/kg. The blood pressure and incidence of apnoea were determined in the two groups during and after the LMA insertion. Results: The haemodynamic states of the patients were not comparable statistically as the heart rate, systolic, diastolic and mean arterial blood pressure were significantly higher and stable in the ketamine-fentanyl group than the propofol-fentanyl group (P < 0.05). The incidence of apnoea was significantly lower in the ketamine-fentanyl group compared with propofol-fentanyl group (P = 0.045), but post-anaesthesia discharge scores were similar, with no significant difference in both groups (P = 0.241). Conclusion: The use of ketamine-fentanyl combination for LMA insertion in paediatric patients was associated with better haemodynamic changes and lower incidence of apnoea when compared with propofol-fentanyl combination.
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    Endometriosis: Evaluation and management in a low-resource country
    (Kenya Medical Association, 2019) Adeniran, Abiodun; Adeoye, Oladapo; Adesina, Kikelomo; Ezeoke, Grace; Ige, O.A.; Imhoagene, Aleakhuei; Akanbi, O.R.; Ibrahim, Kazeem
    background: Endometriosis is a chronic debilitating gynaecologic condition that negatively affects the health, economic, social and psychological lives of women. Though a gynaecological condition, it can affect other systems in the body. objective: To describe the presentation, evaluation and treatment of endometriosis among gynaecological patients at a tertiary centre in Ilorin, Nigeria. Methods: A retrospective descriptive study of all women managed for endometriosis over a three and half year period at a tertiary centre. A list of all individuals with the condition was compiled, the case files were retrieved and the relevant data extracted. The result was presented in tables. results: Endometriosis constituted 1.3% of gynaecological admissions and 0.6% of gynaecology clinic visit during the study period. It affected reproductive-age women with mean age 32.8 years and modal age 31-35 years (35.3%). The women were mostly nulliparas (13;76.5%) with normal menstrual cycle (13;76.6%) and duration of menstruation (16;94.1%). Eleven (64.7%) had multiple gynaecological complaints and additional extra-pelvic lesions respectively. Sixteen (94.1%) had coexisting co-morbidity, of these 9 (56.3%) was in the thoracic region. The common medical treatment offered was gonadotrophin-releasing-hormone analogues (8; 47.1%), 6(35.3%) had medical while 11(64.7%) has combined medical and surgical management; diagnosis was by histology in 11(64.7%). conclusion: Endometriosis remains a disease of reproductive-age women commonly associated with coexisting non-gynaecologic manifestations necessitating combined medical and surgical management.
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    Open Heart Surgery in Ilorin: Case Report and Experience with the First Two Cases
    (College of Health Sciences, University of Ilorin, Nigeria, 2017) Adeoye, P.O.; Abdulkadir, M.B.; Kolo, P.M.; Ige, O.A.; Afolabi, J.K.; Ogunmodede, James Ayodele; Olawumi, H.O.; Adeboye, M.A.N.; Adedoyin, O.T.
    Open heart surgery is uncommonly done in Nigeria and restricted to few centres despite the burden of congenital heart disease. We present our first experience with open heart surgery at the University of Ilorin Teaching Hospital. A 15 years old female adolescent presented with a 2 years history of easy fatigability, dyspnoea on exertion and chest pain. Echocardiography revealed a large ostium secundum atrial septal defect. She had patch closure of the atrial septal defect. The second case was a 7 years old female child with stunted growth. Echocardiography confirmed an ostium secundum atrial septal defect and severe pulmonary valvular stenosis. She had patch closure of the atrial septal defect and pulmonary valvulotomy. Both patients are being followed up and doing well. The hospital has achieved a major milestone by performing its first open heart surgeries. A coordinated team approach yields good results in the development of capacity and facilities for performing open heart surgery in Nigeria.
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    Open Ligation of Persistent Ductus Arteriosus Still a Reliable Modality in a Resource‑Challenged Environment
    (Medknow, Wolters Kluwer Health, India, 2022-01-29) Adeoye, P.O; Akanbi, O.R; Azeez, L.A; Ofoegbu, C.K.; Olaoye, I; Abdulkadir, Mohammed Baba; Ige, O.A.
    Background: Persistent ductus arteriosus (PDA) is one of the most common congenital heart diseases, and its management ranges from pharmacologic, surgical, or catheter‑based therapy. Advances in cardiac surgery have made ligation of PDAs a safe surgical procedure. Objective: The objective of this study is to evaluate the experience in the surgical management of PDA at the University of Ilorin Teaching Hospital. Subjects and Methods: Retrospective data of patients who had open ligation of PDA at the Thoracic and Cardiovascular Surgery division University of Ilorin Teaching Hospital from 2006 to 2021 were reviewed. Results: Of the 27 patients (10 males and 17 females), 25 had left posterolateral thoracotomy for PDA ligation. Their median age was 1 year. The mean weight was 7.75 kg with a range of 3.9–20 kg. The mean preoperative PDA size by echocardiography was 5.06 mm and a range of 3–8 mm. Krichenko type B was the most common morphology seen in eight of the patients. The majority (18) had no other comorbidities, whereas two had cardiac and seven had extracardiac comorbidities. Two patients developed pulmonary complications (pneumonia and pulmonary edema), one patient developed surgical site infection and one patient postoperative pyrexia and seizures which resulted in the only observed mortality. Conclusions: We report our experience with surgical ligation of PDA the only treatment modality at our institution currently as we lack the capacity for transcatheter closure.