Open Ligation of Persistent Ductus Arteriosus Still a Reliable Modality in a Resource‑Challenged Environment


Background: Persistent ductus arteriosus (PDA) is one of the most common congenital heart diseases, and its management ranges from pharmacologic, surgical, or catheter‑based therapy. Advances in cardiac surgery have made ligation of PDAs a safe surgical procedure. Objective: The objective of this study is to evaluate the experience in the surgical management of PDA at the University of Ilorin Teaching Hospital. Subjects and Methods: Retrospective data of patients who had open ligation of PDA at the Thoracic and Cardiovascular Surgery division University of Ilorin Teaching Hospital from 2006 to 2021 were reviewed. Results: Of the 27 patients (10 males and 17 females), 25 had left posterolateral thoracotomy for PDA ligation. Their median age was 1 year. The mean weight was 7.75 kg with a range of 3.9–20 kg. The mean preoperative PDA size by echocardiography was 5.06 mm and a range of 3–8 mm. Krichenko type B was the most common morphology seen in eight of the patients. The majority (18) had no other comorbidities, whereas two had cardiac and seven had extracardiac comorbidities. Two patients developed pulmonary complications (pneumonia and pulmonary edema), one patient developed surgical site infection and one patient postoperative pyrexia and seizures which resulted in the only observed mortality. Conclusions: We report our experience with surgical ligation of PDA the only treatment modality at our institution currently as we lack the capacity for transcatheter closure.



Left thoracotomy, patent ductus arteriosus, persistent ductus arteriosus ligation, persistent ductus


9. Adeoye, P.O., Akanbi, O.R., Azeez, L.A., Ofoegbu, C.K., Olaoye, I., Abdulkadir, M., Ige, O.A. (2020). Open ligation of persistent ductus arteriosus still a reliable modality in a resource- challenged environment. Nigerian Journal of Cardiovascular and Thoracic Surgery, 5(2), 43-46