Browsing by Author "Ibraheem, Rasheedat Mobolaji"

Now showing 1 - 14 of 14
  • Item
    Ackee Fruit Poisoning in Eight Siblings: Implications for Public Health Awareness
    (American Journal of Tropical Medicine and Hygiene, 2015) Katibi, O.S.; Olaosebikan, R.R; Abdulkadir, Mohammed Baba; Ogunkunle, T.O; Ibraheem, Rasheedat Mobolaji; Murtala, R
    Ackee apple fruit is a native fruit to Jamaica and some parts of west Africa. Its toxicity known as “Jamaican vomiting sickness” dates back to the nineteenth century. However, there is a dearth of reported published data on toxicity from Nigeria where it is popularly known in the southwest as “ishin.” We report a case series of eight previously well Nigerian siblings who presented at various intervals after ingestion of roasted seeds and aril of the ackee fruit.
  • Item
    Burden and outcome of respiratory morbidities among children and adolescents with sickle cell disease—A retrospective review of emergency presentations in some Nigerian tertiary institutions.
    (Public Library of Science, United States of America, 2024-05-16) Ibraheem, Rasheedat Mobolaji; Abdulkadir, Mohanned Baba; Aliu, Rasaki; Issa, Amudalat; Ibrahim Olayinka Rasheed; Bello, Abdulafeez Oyesola; Abubakar, Fatima Ishaq; Oloyede, Precious Iso; Olasinde, Yetunde Toyin; Briggs, Datonye Christopher; Bashir, MuhammedFaruk; Salau, Qassim Olakunle; Garba, Bilkisu Ilah; Ameen, Hafsat Abolore; Suleiman, Mohammed Bello; Bewaji, Temitayo Olubunmi; Shina, Hassan Kamiludeen
    Background Despite the huge burden of sickle cell disease (SCD) among Nigerian children, the burden and outcome of respiratory illnesses remain undocumented. Thus, we aimed to describe the spectrum and outcome of respiratory illnesses among SCD childrenand adolescentadmissions in ten Nigerian tertiary hospitals. Method A retrospective review of the SCD admission records of children and adolescents with a confirmed diagnosis of respiratory illnesses from 2012 to 2021 in ten tertiary health facilities across five geopolitical zones in Nigeria was conducted. The data, collectedbetween March and June 2023, included the age, sex, diagnosis, complications, duration and outcome of hospitalization. Results Of the 72,333 paediatric admissions, 7,256 (10.0%) had SCD; the proportion of SCD from the total admission ranged from 2.1 to 16.3% in the facilities. Of the 7,256 children and adolescents with SCD, 1,213 (16.7%) had respiratory morbidities. Lower respiratory disease was the most common (70.0%) respiratory entity and the majority were pneumonia (40.1.0%), followed by acute chest syndrome (26.7%). Seventeen (1.4%) patients died; all had lower respiratory diseases [(acute chest syndrome ACS (11, 64.7%), pneumonia; 5, 29.4%, and asthma (1, 5.9%). Based on the proportion of deaths among overall SCD, the 17 death cases contributed 9.4% (95% CI 5.9 to 14.5). Factors associated with deaths included duration of hospitalization less than 72 hours and lower respiratory tract diseases. Conclusion Sickle cell disease is a major contributor to hospitalization among Nigerian children and adolescents, with high respiratory morbidity and mortality. Pneumonia and acute chest syndrome were associated with mortality, andthe highest risk of death within the first 72 hours.
  • Item
    Clinical presentation and predictors of hospital mortality of diphtheria in Nigeria, July 2023 to April 2024: a single-center study
    (BioMed Central Limited, Springer Nature, United Kingdom, 2025-01-02) Alege, Abdurrazaaq; Ibrahim, Olayinka Rasheed; Ibraheem, Rasheedat Mobolaji; Aladesua, Olajide; Lugga, Abubakar S.; Yahaya, Yunusa Y.; Sanda, Abdallah; Suleiman, Mohammed B
    Background Despite recurrent outbreaks of diphtheria in Nigeria, there is a lack of in-depth analysis of hospitalization outcomes. Herein, we describe the sociodemographic, clinical, and laboratory features associated with hospitalization outcomes (defined as death or discharge) during the recent diphtheria outbreak in Nigeria. Methods This prospective observational study included 246 confirmed diphtheria cases managed in a dedicated isolation ward of a health facility in northwestern Nigeria from July 1, 2023, to April 30, 2024. We analyzed clinical and laboratory features, immunization status, and socio-demographics in relation to hospitalization deaths using SPSS version 29. Results The median age (interquartile range) was 7.00 (4–10) years and 49.6% (122) were aged 5–10 years. Common clinical features were fever (95.9%), sore throat (91.9%), painful swallowing (90.7%), pseudomembrane (93.1%), and cervical-submandibular lymphadenopathy (91.5%). Most children were unvaccinated (158; 64.2%), 199 (80.9%) received diphtheria antitoxin, and both were related to outcomes. Mortality rate was 23.5% (58/246). After adjusting for confounders, predictors of hospitalization deaths were neck swelling with an adjusted odds ratio (AOR) of 9.80 (95% CI 1.68–56.47), abnormal respiratory findings (AOR, 149.99 [95% CI, 15.60–1442.02] ), hypoxemia (AOR, 37.79 [95% CI, 4.26–331.96] ), and elevated serum creatinine above 1.5 mg/dL (AOR 107.78, 95% CI, 7.94–1462.38). Conclusions Diphtheria is a significant burden in Nigeria, particularly among children. Neck swelling, hypoxemia, abnormal respiratory findings, and impaired renal function were predictive of hospitalization death. Although antitoxin and vaccination were related to outcomes, they did not predict hospitalization death.
  • Item
    A comparative analysis of mothers preference for specific type of phone-derived reminders for routine immunization appointments in Ilorin, Nigeria
    (Journal of Medicine in the Tropics, 2018) Ibraheem, Rasheedat Mobolaji; Akintola, Moshood Adebayo; Abdulkadir, Mohammed Baba; Adeboye, M.A.N.; Mohammad, M.
    Background: Forgotten immunization appointment is a factor associated with low immunization uptake in Nigeria which could be addressed by a reminder-based intervention. Thus, there is a need to identify the type of reminder which would be preferred by the recipients which was the aim of this study conducted in Ilorin, Nigeria. Materials and Methods: A descriptive, cross-sectional study involving 363 mothers was conducted at two public-based immunization centers. Responses on willingness to receive text message or call reminders, preferred timing of appointment, and language of communication, willingness to pay, antenatal, and delivery characteristics were obtained via questionnaires. Data were analyzed with the Statistical Package for the Social Sciences version 20.0 software (IBM Corporation, Virginia, USA). Results: Text messages were preferred by 189 (52.1%) mothers and call by 174 (47.9%) mothers. A day prior to the scheduled appointment was the preferred timing by 322 (88.7%) mothers. The local language was preferred by 133 (76.4%) mothers who wanted calls, and 154 (81.5%) mothers who preferred text messages wanted English language. Logistic regression identified the odds of mothers preference for text message compared with calls was eightfold to fivefold among those aged 21–25 and 31–35 years, respectively compared with those aged <21 years, with each P < 0.005. Willingness to pay at most 50 naira for the reminders increased by eightfold among those who preferred text messages compared with calls (odds ratio 8.4; 95% confidence interval 2.8–25.1). Conclusion: Phone-derived reminders are a possible deployable tool for increasing immunization coverage in Nigeria. The optimal timing for sending reminders is the day preceding the appointment. Call reminders are preferred delivered in the local language, whereas English is preferred for text messages.
  • Item
    A comparative study of the ownership and utilization of insecticide treated nets in household of children with uncomplicated malaria in Nigeria
    (Tropical Journal of Health Sciences, 2016) Abdulkadir, Mohammed Baba; Ibraheem, Rasheedat Mobolaji; Ahmed, A.O.; Oyebamiji, Joshua
    The objective of the study was to determine insecticide treated net possession and usage; and factors associated with their utilisation in a cohort of children with uncomplicated malaria. A cross-sectional study was conducted at a secondary level health facility. Subjects were children with uncomplicated malaria and their caregivers. Inclusion criteria were children presenting with fever and have a positive rapid diagnostic test for malaria. Children with severe malaria were excluded. The subjects were recruited consecutively during the period of highest malaria transmission. Information was obtained on insecticide treated net ownership and utilisation from the caregivers. One hundred and thirteen children were recruited. Seventy one of the children were aged less than five years. Insecticide treated net ownership rate was 52.2% and utilisation rate was 62.7%. Age less than five years was the only factor significantly associated with an increased likelihood of net ownership (p=0.03). In conclusion, insecticide treated net ownership and utilisation among children with uncomplicated malaria in Nigeria is low and children aged less than five years are associated with a higher likelihood of household net ownership.
  • Item
    Cross- sectional survey of school teachers knowledge of Ebola virus disease in Ilorin
    (Tropical Journal of Health Sciences, 2016) Abdulkadir, Mohammed Baba; Abdulkadir, Zainab Ajoke; Ibraheem, Rasheedat Mobolaji; Afolabi, Joseph Kolawole
    The current outbreak of Ebola virus disease is the largest ever. It had led to major disruptions in academic calendars due to closing of schools. However, recent successes in curtailing the epidemic had led to the reopening of schools. School teachers who are in close contact with children should have the necessary knowledge regarding the disease and the capacity to carry out appropriate actions for ill children. We sought to determine the knowledge of primary and secondary school teachers in privately owned schools regarding Ebola virus disease. The study is a descriptive questionnaire based survey on knowledge of teachers regarding EVD. Study participants were primary and secondary school teachers working in privately owned schools. A purposive sampling technique was used in selecting participants. One hundred questionnaires were distributed with an 89% response rate. The mean age of the teachers was 34.18 years ± 8.49. Majority (87.6%) of the teachers recognized close contact with an infected person as a method of transmission. Most (68.5%) of the teachers were able to correctly identify six or more common symptoms of EVD. Over 70% of the teachers recognized the need to isolate suspected/ confirmed cases, frequent hand washing the use of hand sanitizers as effective strategies for the prevention of EVD. School teachers in the current study have a good knowledge of EVD and strategies for its prevention.
  • Item
    Determinants of Timely Presentation for Birth Dose Vaccination at an Immunization Centre in North-central Nigeria
    (Annals of Global Health, 2019) Ibraheem, Rasheedat Mobolaji; Abdulkadir, Mohammed Baba; Akintola, M.A.; Adeboye, M.A.N.
    Background: Timely receipt of immunization is an essential prerequisite to ensure early protection of the child. However, a low proportion of children in Nigeria benefit from the timely administration of the birth dose vaccines. Objectives: These were identification of factors associated with timely presentation and reasons for presentation beyond 24 hours at an immunization centre in Ilorin, Nigeria. Method: A descriptive cross-sectional study involving 480 mother-infant pairs was conducted at an immunization centre. Socio-demographic, antenatal care (ANC) and delivery details, infant’s birthday and day of presentation for vaccination were recorded. Logistic regression was used to identify factors associated with time to presentation within day one. Findings: 239 (49.8%), 421 (87.7%) and 454 (94.6%) babies were vaccinated within days one, seven and 14 respectively. Post-secondary education level of mothers (OR = 3.60; 95% C.I: 1.30–9.91), antenatal care attendance (OR = 9.55; 95% C.I: 1.75–52.12), and hospital delivery (OR = 6.36; 95% C.I: 1.33–30.38) were associated with presentation within day one. Having correct knowledge of the immunization schedule increased the odds of early presentation by three times, p = 0.025. The commonest reason for presentation after day one for vaccination was weekend/public holiday delivery identified in 83 (35.2%) mother-infant pairs. Conclusion: Hospital delivery, attendance at antenatal care, postsecondary education and knowledge of the immunization schedule were factors associated with timely presentation for birth dose vaccination. Strategies to improve timeliness of the birth dose vaccination should target babies delivered outside the hospital as well as during weekends in the hospital.
  • Item
    Mobile phone call reminders to improve oral rehydration salt and zinc adherence for acute diarrhea in children: a single-center, randomized controlled trial.
    (BioMed Central Limited, Springer Nature, United Kingdom, 2024-09-06) Kayode-Alabi, Titilayo Funmilayo; Ibraheem, Rasheedat Mobolaji; Alabi, Kayode Olusegun; Bolakale, Aishat Oluwatoyin; Ernest, Samuel Kolade
    Background Low-osmolarity oral rehydration salt (ORS) and zinc therapy effectively manage diarrhea in children under five years of age, offering both short- and long-term benefits. Despite this, caregivers’ adherence to ORS and zinc is often unsatisfactory due to factors such as forgetfulness, resolution of symptoms, and underestimation of the disease’s severity. This study assessed the effect of mobile call reminders on ORS and zinc tablet adherence among children with acute diarrhea in a secondary-level health facility in Kwara State, Nigeria. Methods Using an open-label, randomized controlled trial design, this study compared caregiver-child pairs with acute diarrhea aged 6–59 months who received standard instructions (SI) alone (control group) and an intervention group (IG) who received SI plus phone call reminders on days three and seven of zinc sulfate therapy. All participants used a pictorial diary to track loose/watery stools and ORS and zinc tablet treatments for ten days. The primary outcome measures were independent and combined adherence to ORS and zinc therapy. The secondary outcomes were independent and combined adherence scores, defined as the percentage of times the ORS was given post-diarrhea and the percentage of prescribed zinc tablets administered out of ten. Results A total of 364/400 mother–child pairs completed the study. The percentage of mothers with full adherence in the intervention group was 82.5% for ORS, 72.1% for zinc, and 58.5% for combined use, compared to 78.8%, 60.8%, and 43.6%, respectively, in the control group. The odds of full adherence to ORS and zinc were 1.6 and 1.7 times higher among intervention mothers [ORS: OR = 1.561, 95% CI = 0.939–2.598, P = 0.085; zinc: OR = 1.671, 95% CI = 1.076–2.593, P = 0.022], and 1.8 times higher for combined use according to WHO guidelines [OR = 1.818, 95% CI = 1.200–2.754, P = 0.005]. The mean adherence scores for the intervention group were higher than those for the control group by 4.1% (95% CI = 0.60–7.60) for ORS, 7.3% (95% CI = 3.74–10.86) for zinc, and 5.7% (95% CI = 3.23–8.17) for the combined treatment. Conclusion Phone reminders can effectively improve consistency of home treatment administered by caregivers for children under five years old.
  • Item
    Reappraisal of respiratory syncytial virus as an aetiology of severe acute lower respiratory tract infections in children younger than 5 years in Nigeria
    (Royal Society of Tropical Medicine and Hygiene., 2019) Oladele, D.M; Oladele, D.P; Ibraheem, Rasheedat Mobolaji; Abdulkadir, Mohammed Baba; Raheem, R.A.; Gobir, A.A; JOhnson, W.B.R
    Background: Acute lower respiratory tract infections (ALRIs) especially severe ALRIs, constitute a global high burden of morbidity and mortality in children <5 y of age and respiratory syncytial virus (RSV) has been documented to a play a major aetiological role. However, Nigerian reports on severe childhood RSV ALRIs are rare and most reports are old. With recent advances in RSV preventive strategy, arises the need for a recent appraisal of RSV infection in children with severe ALRI. The current study thus set out to determine the preva lence of RSV infection among hospitalized children <5 y of age and describe the related social determinants. Methods: We performed a descriptive cross-sectional study conducted over 1 y of 120 children, ages 2–59 months, diagnosed with ALRI. Relevant data were obtained and an antigen detection assay was used for viral studies. Results: The prevalence of RSV infection was 34.2% and its peak was in the rainy months. The proportion of infants in the RSV-positive group was significantly higher than that in the RSV-negative group (82.9% vs 54.4%; p=0.002). These findings were largely consistent with those of earlier reports. Conclusions: RSV has remained a common cause of severe ALRI in infants, especially during the rainy months in Nigeria. It is thus suggested that more effort be focused towards implementing the current global recommendations for the prevention of RSV-associated LRI, particularly in infants
  • Item
    Reference values for the six-minute walk test in Nigerian adolescents aged 10 to 18 years
    (College of Health Sciences, Osun State University, 2019) Abdulkadir, Mohammed Baba; Ibraheem, Rasheedat Mobolaji; Akintade, O.O; Suberu, H.D.; Issa, A; Alabi, K.O
    Objective: To determine baseline six-minute walk distance in Nigerian adolescents and establish its relationship with age, gender and anthropometric parameters. Methods: One hundred and eighty healthy adolescents (10 – 18 years) were recruited from three schools. Six-minute walk test was conducted as described by the American Thoracic Society. Demographic and anthropometric characteristics were related to achieve six-minute walk distance. Amathematical formula for predicting six-minute walk distance was generated. Results: The mean ± SD six-minute walk distance was 590.1 ± 72.02 m and was significantly longer in males (p= 0.001) among adolescents aged 10- 16 years. Age was the only characteristic significantly associated with six-minute walk distance following multiple linear regression analyses. The formulae, [six-minute walk distance = 317.3 + 21.5 x age (years) in males and 117 + 33.0 x age (years) in females] closely approximated to measured six-minute walk distance. Conclusion: This study has derived reference values for 6-minute walk test in adolescents; the use of these reference values should consider age and gender variations.
  • Item
    Relationships between troponin I and hypoxic–ischemic encephalopathy among newborn babies
    (Saudi Neonatology Society, 2021) Issa, A; Abdulkadir, Mohammed Baba; Ibraheem, Rasheedat Mobolaji; Ibrahim, O.R; Bello, S.O; Suberu, H.D.; Sanusi, I
    Background: A proper evaluation of cardiovascular status, with a view to ensuring early diagnosis of cardiac dysfunction and prompt intervention where necessary, is a recognized approach in the management of asphyxiated neonates. Hence, we determined the levels of a cardiac biomarker (troponin I), its relationship with disease severity, and mortality in asphyxiated neonates with hypoxic–ischemic encephalopathy (HIE). Methods: This was a descriptive study that involved 85 asphyxiated, term appropriate‑for‑gestational age newborn babies with HIE (subjects) and 85 healthy controls within the first 72 h of life. Asphyxiated neonates were classified into HIE stages using Sarnat and Sarnat staging. Blood samples were collected between 24 and 72 h of life to determine the level of troponin I using enzyme‑linked immunosorbent assay. The asphyxiated babies were followed up till discharge or death. Results: The median interquartile range level of troponin I in the subjects was higher compared with the controls, 1.26 (0.97–3.16) ng/ml versus 0.79 (0.79–1.42) ng/ml, P < 0. 001. The levels of troponin I in HIE I, HIE II, and HIE III were 1.26 (1.00–2.37) ng/ml, 1.11 (0.86– 2.96) ng/ml, and 3.58 (1.34–5.58) ng/ml, respectively. Nonsurvivors had a higher cardiac troponin I (4.00 [2.30–6.34] ng/ml) compared with survivors (1.21 [0.95– 2.37] ng/ml), P = 0.015. Conclusion: Cardiac troponin I was significantly higher in asphyxiated subjects compared with healthy controls. Elevated troponin I was associated with higher mortality. Troponin I levels in the first 72 h can help as a prognostic indicator of HIE in term babies
  • Item
    Relevance and challenges of neuroimaging for childhood tuberculous meningitis diagnosis in a resource-constraint country: A case report and literature review
    (College of Medicine, University of Osun State, 2023-09-30) Ibraheem, Rasheedat Mobolaji; Ariyibi, Solomon O.; Gobir, Aishatu A; Johnson, AbdulWahab R.; Yusuf, Mohammed J; Adeleke, N.A.
    Objective: Tuberculous meningitis (TBM) may be an undiagnosed cause of childhood mortality or neurologic sequelae. Cranial computed tomography (CT) scan remains a relevant diagnostic and prognostic tool amidst negative cerebrospinal fluid or sputum findings for tuberculous meningitis (TBM) diagnosis. Delays in diagnosis and treatment increase morbidity in resource-constraint countries. Case report: A seven-year-old boy was referred with three weeks history of fever, progressive body weakness, aphasia and unconsciousness (three days). He had right cranial nerve III palsy, generalized hypertonia, and hyperreflexia in right lower limbs. All tuberculosis tests were negative except the cranial CT findings of leptomeningeal enhancement with basilar involvement and evidence of obstructive hydrocephalus. He was managed with anti-tuberculous drugs, prednisolone, ventriculoperitoneal shunt, and physiotherapy, and made a significant recovery after a year of anti-tuberculosis treatment. Conclusion: The cranial CT scan findings facilitate TBM diagnosis for which prompt treatment commencement is crucial for a good outcome.
  • Item
    Socio-demographic and clinical factors predicting time to presentation for children with pneumonia in Ilorin, Nigeria
    (Alexandria Journal of Medicine, 2018) Ibraheem, Rasheedat Mobolaji; Abdulkadir, Mohammed Baba; Gobir, Aishatu A; Johnson, Wahab Babatunde Rotimi
    Background: Pneumonia is a major contributor to morbidity and mortality in children, and the time to presentation is a recognized contributor towards disease severity and outcome. Objectives: The current study aimed to explore the influence of some socio-demographic and clinical factors in children with pneumonia on the time to presentation at a health facility in Ilorin, North Central Nigeria. Materials and method: A prospective cross-sectional study of 167 children with pneumonia was done. The duration of the various symptoms and first presentation to a health facility was obtained. Time to presentation was categorized as 0–2 days (early), 3–5 days (intermediate) and greater than five days (late). Multinomial logistic regression analysis was used to identify significant predictors of either early or intermediate presentation compared with late presentation. A p-value of less than 0.05 was considered significant. Results: Fifty-one (30.5%) children with pneumonia had an early presentation, 73 (43.7%) had intermediate presentation and 43 (25.7%) were late in presentation. Predictors of early presentation were younger age (OR 0.96, 95%CI 0.93–0.99), higher respiratory rates (OR 1.03, 95%CI 1.01–1.06) and bronchopneumonia (OR 6.93, 95%CI 1.52–31.63). Predictors of intermediate presentation were families with few number of children (OR 0.73, 95%CI 0.57–0.92) and bronchopneumonia (OR 3.41, 95%C.I. 1.02–11.38). Conclusion: Infancy and families with few children are socio-demographic features that are likely to determine early-to-intermediate presentation of children with pneumonia while high respiratory rates and bronchopneumonia are disease related factors that predict early presentation.
  • Item
    Trends in Pediatric Tuberculosis Diagnosis Utilizing Xpert Mycobacterium tuberculosis/Rifampicin in a Poor-Resource, High-Burden Region: A Retrospective, Multicenter Study
    (Asian African Society of Mycobacteriology, 2023-01) Garba, Maria Ahuoiza; Ogunbosi, Babatunde Oluwatosin; Musa, Abdullahi; Ibraheem, Rasheedat Mobolaji; Alao, Micheal Abel; Jiya-Chitumu, Eunice Nnaisa; Olorukooba, Abiola Aira; Makarfi, Hauwau Umaru; Tahir, Yusuf; Ibrahim, Hafsat; Saidu, Adamu Adamu; Bashir, Muhammad Faruk; Odimegwu, Chioma Laura; Ayuk, Adaeze; Alkali, Nura Hamidu
    Background: The burden of tuberculosis (TB) in Nigeria remains high, and diagnosis in children, a challenge. We aimed to document yield from Xpert Mycobacterium tuberculosis/rifampicin (MTB/RIF) as a mode of diagnosis for children and the variables associated with a positive result. Methods: This was a retrospective review of TB treatment cards of children aged 0–15 years managed from January 2017 to December 2021 across six public tertiary institutions in Nigeria. The data obtained were analyzed using the descriptive and inferential statistics. Statistical significance was set at P < 0.05. Results: Of 1489 children commenced on TB treatment, 1463 (97.9%) had sufficient data for analysis the median age of study participants was 60 months (interquartile range [IQR]: 24, 120), and 814 (55.6%) were males. Xpert MTB/RIF test was performed in 862 (59%) participants and MTB was detected in 171 (19.8%) participants, of which 6.4% (11/171) had RIF resistance reported. The use of Xpert MTB/RIF rose from 56.5% in 2017 to 64% in 2020 but fell to 60.9% in 2021. We found that older age (> 10 years), the presence of pulmonary TB (PTB), and a negative human immunodeficiency virus (HIV) status were associated with positive Xpert MTB/RIF tests (P = 0.002, 0.001, and 0.012, respectively). Conclusion: The utilization of Xpert MTB/RIF in children increased in the years before the COVID-19 pandemic. Factors associated with MTB detection by Xpert MTB/RIF include older age, the presence of PTB, and a negative HIV status. Clinical and radiological evaluation continues to play vital roles in the diagnosis of childhood TB in Nigeria.