Browsing by Author "Fawibe, A. E."

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    Normal CD4 Count Range among Healthy Nigerian Population in Ilorin
    (2014) Afolabi, J.K.; Fadeyi, A; Desalu, O O.; Durotoye, I. A; Fawibe, A. E.; Adeboye, M.A.N; Olawumi, H.O; Babatunde, A.S; Ernest, S.K; Aderibigbe, S.A; Saadu, R; Salami, A.K; Aboyeji, A.P
    Background: For the establishment and monitoring of the immune status, CD4 count is critical. Objectives: To determine the CD4 count range of apparently healthy Nigerians resident in Ilorin and compare with the national value. Methods: An automated blood analyzer was used to determine the full blood count and CD4 count. The percentage of CD4 count was derived by using other variables. Results: Of the 1205 participants, the reference CD4 count (percentage of CD4) range for adult was 400 to 1288 cells/mm3 (19%-48%) and for children was 582 to 3652 cells/mm3 (17%-50%). CD4 count and percentage of CD4 were significantly (P ¼ .001) higher in females than in males, and the CD4 count declined significantly with increasing age (r ¼ .174, P .0001). The percentage of CD4 count shows less variation with age (r ¼ .051, P ¼ .076). Adult residents of Ilorin had significantly lower absolute mean CD4 count (808 + 260) than that of the national reference values of 847.0 + 307.0 cells/mm3 (P ¼ .001). Conclusion: We therefore advocate the use of CD4 count range derived in this study is lower than that of the national reference values.
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    Normal CD4+ Cell Count Range Amongst Healthy Nigerian Population In Ilorin,
    (International Association of Providers of AIDS Care., 2014) Afolabi, J. K.; Fadeyi, A; Desalu, O. O.; Durotoye, I. A.; Fawibe, A. E.; Adeboye, M. A. N.; Olawumi, H. O.; Babatunde, A. S.; Ernest, S. K.; Aderibigbe, S. A.; Saadu, R.; Salami, A. K.; Aboyeji, A. P.
    Background: For the establishment and monitoring of the immune status, CD4 count is critical. Objectives: To determine the CD4 count range of apparently healthy Nigerians resident in Ilorin and compare with the national value. Methods: An automated blood analyzer was used to determine the full blood count and CD4 count. The percentage of CD4 count was derived by using other variables. Results: Of the 1205 participants, the reference CD4 count (percentage of CD4) range for adult was 400 to 1288 cells/mm 3 (19%-48%) and for children was 582 to 3652 cells/mm 3 (17%-50%). CD4 count and percentage of CD4 were significantly (P 1⁄4 .001) higher in females than in males, and the CD4 count declined significantly with increasing age (r 1⁄4 .174, P .0001). The percentage of CD4 count shows less variation with age (r 1⁄4 .051, P 1⁄4 .076). Adult residents of Ilorin had significantly lower absolute mean CD4 count (808 + 260) than that of the national reference values of 847.0 + 307.0 cells/mm 3 (P 1⁄4 .001). Conclusion: We therefore advocate the use of CD4 count range derived in this study is lower than that of the national reference values.
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    Profile and Outcome of Unilateral Tuberculous Lung Destruction in Ilorin, Nigeria
    (WEST AFRICAN JOURNAL OF MEDICINE, 2011) Fawibe, A. E.; Salami, A. K.; Oluboyo, P. O.; Desalu, O. O.; Odeigha, L.O.
    BACKGROUND: Unilateral tuberculous lung destruction is a serious chronically disabling and often fatal complication of pulmonary tuberculosis. A few previous studies have dealt with some aspects of this entity among Nigerians with pulmonary tuberculosis but these studies may not truly reflect its current trends. OBJECTIVE: To describe the presenting profiles and outcome of unilateral tuberculous lung destruction among patients with pulmonary tuberculosis. METHODS: The study was a chart review of the medical records of adult patients with pulmonary tuberculosis complicated by unilateral lung destruction seen between January 1999– December 2008. Data extracted included demographic, and outcome of treatment. The clinical features, sputum results and illustrative cases are presented. RESULTS: Unilateral lung destruction complicated 74(1.3%) of 5,926 pulmonary tuberculosis cases seen over the review period. Most cases occurred in males [45(60.8%)] and they were predominantly [51(68.9%)] below 40 years of age. Most of them [52(70.2%)] presented after six months of symptoms. Forty-seven (63.5%) of them had had previous exposure to antituberculosis drugs. The left lung was affected in 49 (66.2%) patients. Only 25 (33.8%) of them were cured while the adjusted mortality rate was 25.5%. Male gender, presence of dyspnoea on mild exertion and right ventricular failure were significantly associated with increased mortality. CONCLUSION: Unilateral tuberculous lung destruction has unacceptably high mortality rate which can be prevented by patient presenting early to the hospital, prompt diagnosis and strict adherence to the standard treatment. WAJM 2011; 30(2): 130–135.