Browsing by Author "Durowade, K.A."
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Item Condom use among HIV sero-concordant couples attending a secondary health facility in North-Central Nigeria(Nigeria Journal of Basic and Clinical Sciences., 2013) Salaudeen, A.G.; Ojotule, A.; Durowade, K.A.; Musa, O.I O.I. & Saka, M.J.; Saka, M. JItem Current Trend of Transfusion Transmissible Infections among Voluntary Blood Donors in North Central Nigeria(College of Health Sciences, University of Ilorin, 2021-07) Durotoye, I.A.; Salaudeen, A.G.; Sanni, E.O.; Durowade, K.A.; Babatunde, A.S.; Olawumi, H.O.; Akande, T.M.; Musa, I.O.Blood transfusion is an integral part of modem medicine which had saved many lives which would have been lost as a result of lack of blood. Although blood is needed for survival, it can also be a medium for the transmission of harmful infectious diseases. This study evaluated current trend of transfusion transmissible infections among voluntary blood donors in Nigeria. This was a descriptive community-based study involving 600 prospective voluntary blood donors among staff and students of 5 tertiary institutions in Kwara and Kogi States. Hepatitis B surface antigen and Hepatitis C antibodies were screened for using Hepatitis B Virus Surface Antigen Bio-Inteco ELISA KIT, and Anti-HCV Bio-Inteco ELISA KIT, respectively. Screening for HIV was done with Enzyme immunoassay method using Human Immunodeficiency Virus (HIV) 1+2 Antigen Antibody ELISA KIT, product of Bio-Inteco HIV Diagnostics, UK. Testing for Syphilis was carried out using Rapid Plasma Reagin (RRR) test. Statistical analysis was done with IBM SPSS version 20. Level of significance was set at p< 0.05 The mean age of the subjects was 21.98 ± 5.17 years. Two thirds of the prospective blood donors were within the second decade of life and more than half were males. The prevalence of Hepatitis B among subjects were 4.7%, Hepatitis C,0.2%, HIV 1% and Syphilis 0%. The prevalence of hepatitis B and HIV were relatively high compared to Hepatitis C and Syphilis among voluntary blood donors, although lower than the prevalence among general population in Nigeria. In order to improve on blood transfusion safety, there is a need to increase public awareness on vaccination for hepatitis B virus, Quality control of screening methods and rational use of Blood.Item Female factor infertility: Laparoscopic evaluation at a public health facility in Ilorin, Nigeria.(College of Medicine KLE University, Belgaum, India, 2017) Omokanye, Lukman O.; Ibrahim, S.; Olatinwo, Abdulwaheed O.; Durowade, K.A.; Raji, S.T.; Biliaminu, S.A.; Salaudeen, A.G.BACKGROUND: Infertility is a problem of global proportions, the majority being the residents of developing countries. The contribution of female factor is assuming a tremendous proportion. Laparoscopy remains an indispensable tool in the evaluation of the fertility potential of these female partners. AIMS: This study was aimed at determining the various causes of female factor infertility among female partners of infertile couple in a tertiary health facility. METHODS: A cross-sectional observational study of ninety seven (97) eligible infertile women who underwent diagnostic laparoscopy between 1st January 2012 and 31st December 2015 were enrolled for the study. The data were analyzed using SPSS/PC version 16.0 and p value was preset at <0.05. RESULTS: The patients aged 21-50 years with a mean age of 33.2 ± 6.6 years. Majority (79.4%) were nulliparous. Fifty (51.5%) had primary infertility. Their duration of infertility ranged from 1to 33years (5.7 ± 5.5 years). Most (63.9%) belong to middle social class and their spouse age ranges between 28-60 years (39.0 ± 7.5). More than a quarter had clomiphene resistant Polycystic Ovarian Syndrome, 19 (19.6%) tubal blockage, 13 (13.4%) uterine fibroid and 10 (10.3%) each had endometriosis, peritubal and ovarian adhesions, ovarian cyst and normal findings respectively. There was significant association between patients’ age, intra-operative findings and tubal patency evaluation on laparoscopy (P < 0.05). CONCLUSION: Laparoscopic procedures are less invasive, more convenient and more precise for diagnosis of infertility in women. The common causes responsible for infertility were polycystic ovarian syndrome, tubal occlusion, uterine fibroid, endometriosis, peri-tubovarian adhesions and ovarian cyst.Item Gynaecological Laparoscopic Surgeries: A 4- Year audit at the University of Ilorin Teaching Hospital, Nigeria(Society of Gynaecology and Obstetrics of Nigeria, 2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Ibrahim, S; Durowade, K.A.; Biliaminu, S.A.; Abdul, I.F.Background: In addition to a shorter hospital stay and better cosmetic results, laparoscopic surgery also offers patients fewer postoperative complications compared to conventional open gynecological surgeries. With expertise and better facilities, it has come to stay as an alternative surgical approach to gynecological diagnosis and treatment. Aims and Objectives: The aim of this study was to assess the indications, intraoperative findings, and types of laparoscopic surgeries performed at the University of Ilorin Teaching Hospital, Ilorin. Materials and Methods: A retrospective observational study of 150 patients who underwent laparoscopic procedures between January 1, 2012 and December 31, 2015, at the Assisted Reproduction Technology (ART) unit of the University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria. Results: Within the period of our review, there were 1,256 gynecological operations and 150 laparoscopies, thus giving a period prevalence of 11.2%. The patients were aged 20–59 years with a mean age of 32.1 ± 3.9 years. Of the 150 laparoscopies, 30 (20%) had diagnostic laparoscopies while 120 (80%) had therapeutic laparoscopies. Of the 30 patients who had diagnostic laparoscopies, 5 (16.7%) presented with primary infertility and 12 (40%) with secondary infertility. The commonest indication for therapeutic laparoscopy was clomiphene‑resistant polycystic ovary syndrome (PCOS) and was found in 81 (67.5%). One (0.7%) was converted to open surgery due to technical difficulties. There was a case of iatrogenic sigmoid colon injury and no mortality recorded. Conclusion: Laparoscopic surgery offers patients a novel choice of intervention that affords establishing definitive diagnosis, shorter hospital stay, better cosmetics, and reduced morbidities/mortalities compared to open gynecological surgeries.Item PATTERN AND EXPLANATORY FACTORS FOR MEDICATION ADHERENCE AMONG PATIENTS WITH HYPERTENSION, DIABETES MELLITUS AND THEIR COMORBIDITY IN A NORTH CENTRAL STATE OF NIGERIA(International Journal of Public Health and Clinical Sciences, 2017) Bolarinwa, O.A.; Bamgbola, O.A.; Sanya, E.O.; Kolo, P.M.; Ameen, H.A.; Durowade, K.A.; Uthman, M.M.B.; Ogunmodede, J.A.; Buliaminu, S.A.; Odeigah, L.O.; Akande, T.M.; Morisky, D.E.Introduction: Hypertension and diabetes are the two most common non-communicable diseases seen in outpatient clinics in Sub-Saharan Africa. Promoting medication adherence is a major clinical hurdle to be crossed in reducing the premature morbidity and mortality associated with these diseases. This study explored factors that predict medication adherence among hypertensive and diabetic patients in Ilorin, Nigeria. Methods: This cross-sectional study was carried out among hypertensive and diabetic patients in outpatient clinics of a teaching hospital in Ilorin, Nigeria. Data was collected from 1,203 patients using a validated Morisky 8-item medication adherence questionnaire. Multivariate ordinal logistic regression was used to model the medication adherence explanatory factors with SPSS version 22. Result: Less than half (43.3%) of the patients were highly adherent to their medication. The relative proportion for high adherence was 42.7%, 35.6% and 49.2% for hypertension, diabetes and both diseases respectively. The odds of medication adherence improving from either low to medium level or from medium to high level was explained by; age, symptoms count, absence of disease complication and absence of drug side effect among the patients. Blood pressure, gender and disease duration did not explain medication adherence among hypertensive and diabetic patients. Conclusion: It is concluded that the discomfort experienced due to the disease condition and the medication regimen are important explanatory factors for patient’s medication adherence in the study setting. This study recommends strategies to reduce multiple drug combinations and promote medication adherence counselling and education among patients.Item Pattern And Explanatory Factors For Medication Adherence Among Patients With Hypertension, Diabetes Mellitus And Their Comorbidity In A North Central State Of Nigeria(Community Health Society of Malaysia., 2017) Bolarinwa, O.A.; Bamgbola, O.A.; Sanya, E.O.; Kolo, P.M.; Ameen, H.A.; Durowade, K.A.; Uthman, M.M.B.; Ogunmodede, James Ayodele; Buliaminu S.A., Odeigah L.O., Akande T.M., Morisky D.E.Introduction: Hypertension and diabetes are the two most common non-communicable diseases seen in outpatient clinics in Sub-Saharan Africa. Promoting medication adherence is a major clinical hurdle to be crossed in reducing the premature morbidity and mortality associated with these diseases. This study explored factors that predict medication adherence among hypertensive and diabetic patients in Ilorin, Nigeria. Methods: This cross-sectional study was carried out among hypertensive and diabetic patients in outpatient clinics of a teaching hospital in Ilorin, Nigeria. Data was collected from 1,203 patients using a validated Morisky 8-item medication adherence questionnaire. Multivariate ordinal logistic regression was used to model the medication adherence explanatory factors with SPSS version 22. Result: Less than half (43.3%) of the patients were highly adherent to their medication. The relative proportion for high adherence was 42.7%, 35.6% and 49.2% for hypertension, diabetes and both diseases respectively. The odds of medication adherence improving from either low to medium level or from medium to high level was explained by; age, symptoms count, absence of disease complication and absence of drug side effect among the patients. Blood pressure, gender and disease duration did not explain medication adherence among hypertensive and diabetic patients. Conclusion: It is concluded that the discomfort experienced due to the disease condition and the medication regimen are important explanatory factors for patient’s medication adherence in the study setting. This study recommends strategies to reduce multiple drug combinations and promote medication adherence counselling and education among patients.Item Pattern and predictive factors of health-related quality of life of patients with hypertension, diabetes and concomitant hypertension with diabetes in Ilorin, Nigeria.(Nigerian Postgraduate Medical College, Lagos, Nigeria., 2016) Bolarinwa, O.A.; Ameen, H.A.; Sanya, E.O.; Kolo, P.M.; Durowade, K.A.; Uthman, MMB; Ogunmodede, James Ayodele; Buliaminu, S.A., Odeigah, L.O. & Akande, T.M.Background: Hypertension and diabetes are the two most important modifiable risk factors for cardiovascular disease (CVD) among Nigerian population. Because of the lifelong nature of the two diseases and the attendant long treatment regimen required, assessing the health‑related quality of life (HRQoL) is an important outcome of these diseases. Objective: This study assessed the pattern and predictive factors of HRQoL among patients with hypertension, diabetes and concomitant hypertension and diabetes using the 36-item short-form version 2. Patients and Methods: A cross-sectional study of 1203 patients attending the outpatient clinics of the University of Ilorin Teaching Hospital, Ilorin; the patients were sampled using systematic random sampling methods. Patients were divided into those with hypertension, diabetes and both diseases. The predictors of physical and mental component summaries of HRQoL were analysed using Norm-based Scoring. The level of significance was set at P < 0.05 and 95% confidence interval. Results: The patients with both diseases have lowest physical HRQoL (45.6), while the diabetic patients have the worst mental HRQoL (39.5). Negative predictors of physical HRQoL across the three groups were: drug regimen (hypertension P < 0.001, diabetes P < 0.001, both P = 0.005), CVD complication (hypertension P < 0.001, diabetes P = 0.025) and accompanying persons (P < 0.001). The positive predictors of physical HRQoL across the three groups were medication adherence (hypertension P < 0.001, diabetes P < 0.001 and both P = 0.002). Similarly, medication adherence was the positive predictor for mental HRQoL across the three groups of patients (hypertension P < 0.001, diabetes P = 0.001 and both P < 0.001). Conclusion: This study provided evidence to show that HRQoL across the three categories of patients in Ilorin, Nigeria, is suboptimal. Drug regimen, medication adherence and support from accompanying persons were important predictive factors of HRQoL.Item Polycyctic Ovarian Syndrome; Analysis of Management Outcomes among Infertile Women at a Public Health Institution in Nigeria(Wolters-Kluwer-Medknow, 2015) Omokanye, Lukman O.; Ibiwoye-jaiyeola, O.A.; Olatinwo, Abdulwaheed O.; Abdul, I.F.; Durowade, K.A.; Biliaminu, S.A.Background: Infertility remains an issue of concern especially to the female partner who bears the brunt of the stigma attributed to the disease in this environment. Among the identified etiological factors for infertility, polycystic ovarian syndrome (PCOS) is the most common endocrine disorder in women of reproductive age that impact on ovulation and conception. Aims and Objectives: The objective of this study was to determine pregnancy outcome following the various modalities of management of PCOS at the University of Ilorin Teaching Hospital (UITH). Materials and Methods: This is a nonrandomized (nonblinded) clinical trial of five therapeutic options for infertile women with PCOS from the Assisted Reproductive Technology (ART) Clinic and Gynaecology Clinic of UITH between January 1, 2011 and December 31, 2013. Results: Of 624 infertile women who presented at ART and general gynecology clinic of UITH, 76 met the Rotterdam criteria for PCOS, giving a prevalence rate of 12.2%. The patients aged 20–44 years with a mean age of 31.5 years. Most 49 (64.5%) of the patients were nulliparous, and more than half (56.6%) belong to the middle social class. Thirty‑four (44.8%) were obese while 22 (28.9%) were overweight. Of the various management options, 48.7% had laparoscopic ovarian drilling; other treatment options offered were the use of clomiphene citrate (CC) alone, CC with metformin, weight reduction, and gonadotropin. Patients were followed‑up within 6–12 months (mean 5.5 ± 1.2 months) following the initial treatment for evidence of laboratory/clinical pregnancy. An overall pregnancy rate of 46.0% was recorded. However, a total of 13 (17.1%) were lost to follow‑up. The highest pregnancy rate (75%) was reported in women managed with CC alone (P = 0.229). Conclusion: PCOS occurs commonly in reproductive age and management outcomes are promising in Nigeria. CC, metformin, and laparoscopic ovarian drilling are of great benefit. Further studies on PCOS in low resource countries are needed.Item Polycystic ovarian syndrome: Analysis of management outcomes among infertile womn at a public health institution in Nigeria(The Nigeria journal of general practice, 2015) Omokenye, L.O.; Ibiwoye-Jaiyeola, O .A.; Olatinwo, A.W.O.; Abdul, I.F.; Durowade, K.A.; Billiaminu, S.A.Item Prevalence of Anaemia at booking in a semi-urban Community in North-Central, Nigeria(National Postgraduate Medical College of Nigeria, 2014) Adewara, E,O; Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Durowade, K.A.; Panti, Abubakar A.; Salaudeen, A.GAims and objectives: This study was carried out to determine the prevalence of anaemia at booking clinic, describe the antenatal booking pattern, and categorize the degree of anaemia with certain demographic features. Subjects and methods: This is a descriptive cross-sectional study carried out over a six month period between 1st April and 30th September 2008. A questionnaire was used to obtain demographic information and venous blood samples were collected from 1,086 consecutive patients who consented to participate in the study. The blood samples were tested for haemoglobin levels, genotype and blood group. Results: Seven hundred and thirty two (67.4%) of the women anaemic at booking. Anaemia was more prevalent among multgravidae than primigravidae (p<0.05). Six hundred and sixty nine (61.6%) had mild anaemia while 40(4.4%) had moderate anaemia and 15 (1.4%) were severely anaemic, of which 8 (53.3%) were below 18 years of age. Varied degrees of anaemia were more common among women aged 24-28 years and in the 3rd trimester of pregnancy (80.7%) (p<0.05). One hundred and seventy (15.7%) of the enrolled booked for antenatal care in the 1st trimester, while 703(64.7%) booked in the 2nd trimester and 213 (19.6%) in the 3rd trimester of their pregnancies. Thirteen (1.2%) had sickle cell anaemia. Conclusion: Prevalence of anaemia at booking remains high in our society. Urgent need for public health education on early antenatal booking and improved literacy level of women is suggested to reduce the burden of anaemia in pregnancy.Item Randomized controlled trial on Transcutaneous Electrical Nerve Stimulation(Society of Gynaecology and Obstetrics of Nigeria, 2014) Omokanye, Lukman O.; Jimoh, A.A.G.; Salaudeen, A.G; Sulaiman, Z.A.; Durowade, K.A.; Adewara, E.O.Item A review of Pregnancy Outcomes Following Intrauterine insemination for Infertile Women at a Public Health Facility in Ilorin, Nigeria(College of Health Sciences, Delta state University, Abraka, Nigeria, 2013) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Biliaminu, S.A.; Durowade, K.A.; Abdul, I.FItem Successful Pregnancy Outcome after in vitro fertilization at a Public Health Facility in Nigeria.(Medical Research Society and College of Medicine and Health Sciences Abia State University., 2014) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Biliaminu, S.A.; Durowade, K.A.We present a case of 31‑year‑old P0+1, who presented with 2 years history of infertility on account of bilateral tubal blockage. She achieved pregnancy and successful delivery following in vitro fertilization at the Assisted Reproductive Technology unit of the Department of Obstetrics and Gynaecology, University of Ilorin Teaching Hospital, Kwara State, Nigeria.