Browsing by Author "Durowade, K A."
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Item Assisted Reproduction Technology: Comparison of Anesthetic Techniques for Oocyte Retrieval in a Tertiary Health Facility in Ilorin(2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Saadu, L.O.; Biliaminu, S.A.; Durowade, K A.; Salaudeen, A.GBackground: Transvaginal ultrasound‑guided oocyte retrieval (TUGOR) technique is minimally invasive and requires shorter time compared to previous techniques. Yet, it is a potentially stressful and painful procedure and thus requires some form of analgesia with or without sedation. The effects of various anesthetic techniques used for TUGOR on reproductive outcomes remain controversial. Aims and Objectives: This study aimed at comparing the efficacy of paracervical block (PCB) and conscious sedation for pain relief and pregnancy outcomes during TUGOR. Materials and Methods: This is a cross‑sectional comparative study of 137 eligible clients that underwent assisted reproduction program in our facility. All clients were treated with antagonist protocol for controlled ovarian hyperstimulation. The choice of analgesia for TUGOR was influenced by clients’ and/or clinicians’ preference. PCB and conscious sedation were administered for TUGOR in 66 and 71 clients, respectively. Pain was assessed using a 10‑cm Visual Analog Scale (VAS), while clients’ overall satisfaction was rated using Likert scoring system. Results: There was no statistically significant difference in the clinical pregnancy, miscarriage, and live birth rates between the two groups. The mean VAS 10‑point scores at 1, 6, and 24 h postretrieval and on the day of embryo transfer were significantly higher for paracervical group. The mean Likert score for conscious sedation group was significantly higher than that of paracervical group. Conclusion: Conscious sedation is superior to PCB as anesthetic/analgesic agent for pain relief and clients’ satisfaction for TUGOR. However, a multimodal approach to anesthesia/analgesia for TUGOR is suggested to further improve overall clients’ satisfaction.Item Assisted Reproduction Technology: Comparison of Clinical outcomes between day 3 and day 5 embryo transfer(College of Medicine KLE University, Belgaum, India, 2018) Omokanye, Lukman O.; Saadu, L.O.; Olatinwo, Abdulwaheed O.; Biliaminu, S.A.; Durowade, K A.; Panti, Abubakar A.; Salaudeen, A.G.BACKGROUND: Embryo transfer (ET) is a critical step in in vitro fertilization (IVF). Selecting the day of transfer for achieving the desired outcomes has been a great challenge. AIMS AND OBJECTIVES: The aim of this study was to compare the pregnancy rates of day 3 and day 5 ET in assisted conception. MATERIALS AND METHODS: This is a longitudinal prospective study of 122 eligible patients that underwent assisted reproduction program in our facility. All patients had controlled ovarian hyperstimulation using antagonist protocol. Patients with four or more zygotes were randomly allocated on day 1 to either day 3 or 5 transfers (58 vs. 64 patients). Fertilization was achieved through conventional IVF. Zygotes were kept in a single‑step medium (Global total®) for day 3 and 5 transfers, respectively. The morphologically best two or three embryos or blastocysts were chosen for transfer in both groups. RESULTS: The overall clinical pregnancy and live birth rates for both groups were 40.2% and 33.6%. There was no statistically significant difference between day 3 and day 5 transfer regarding clinical pregnancy rates (36.2% vs. 43.8% [P = 0.51]), live birth rates (27.6% vs. 9.1% [P = 1.0]), twinning rates (18.8% vs. 20% [P = 1.0]), and rates of early pregnancy loss (8.6% versus 4.7% P = [0.2]). CONCLUSION: In this study, the clinical outcomes of blastocyst transfer are similar to day 3 ET. This underscores the need for patient selection for the choice of days of ET. Further controlled randomized prospective studies with larger sample sizes are recommended.Item Assisted Reproduction Technology: Perceptions among infertile couples in Ilorin, Nigeria.(A taif University Saudi, 2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Durowade, K A.; Raji, S.T.; Biliaminu, S.A.; Salaudeen, A.GBackground: Infertility is a global health problem and a socially destabilizing condition for couples carrying several stigmas and a cause of marital disharmony. Assisted reproduction technologies (ARTs) offers a chance at parenthood to couples, who until recently would have had no hope of having a “biologically related” child. Aims and Objectives: This study aimed to determine the awareness and perception of ART services among infertile couples at a public health facility in Ilorin, Nigeria. Materials and Methods: This is a cross‑sectional descriptive study of consecutively consenting infertile couples seen at the ART unit of the Department of Obstetrics and Gynaecology, University of Ilorin Teaching Hospital, Ilorin, between January 1, 2012, and December 31, 2015. Results: The patients aged 22–52 years with a mean age of 36.1 ± 6.6 years and mean duration of infertility of 7.3 ± 5.8 years. Most (60.8%) belonged to middle social class. Of the 559 infertile couples interviewed, 87.3% were aware of ART services. Less than half (48.8%) were aware of surrogacy while majority (85.7%) rejected the use of surrogate mother. Reasons to decline surrogacy were desire to carry one’s own child (51.7%) and “do not like the idea” (22.3%). Female partner age, duration of infertility, and religion had a significant influence on acceptance of donor egg (P < 0.05). Conclusion: Despite the high level of awareness of ART, its low utilization remains a gap in the delivery of these services. Government and nongovernmental agencies need to institute interventions to stem the trend.Item Assisted Reproductive Technology: Experience from a Public Tertiary Institution in North Central Nigeria(Association of Fertility and Reproductive Health, 2016) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Saadu, L.O.; Biliaminu, S.A.; Durowade, K A.; Panti, Abubakar A.Background: According to the World Health Organization, more than 180 million couples globally suffer from infertility, the majority being residents of developing countries. Assisted reproductive technologies (ARTs) offer a chance at parenthood to couples, who until recently would have had no hope of having a “biologically related” child. Objectives: This study aimed to determine pregnancy outcomes following assisted conception. Materials and Methods: This is a prospective study of 104 clients who underwent the procedure of ART between January 1, 2012 and December 31, 2016 at the ART unit of University of Ilorin Teaching Hospital, Ilorin, Nigeria. Results: Of the 510 clients who had infertility consultation at the ART clinic, 104 (20.4%) underwent ART procedures. The patients aged 27–46 years with a mean age of 33 ± 4.0 years. More than half (58.7%) had primary infertility. Their duration of infertility ranged from 1 to 20 years (4.6 ± 2.9 years). Majority (81.7%) had conventional in vitro fertilization while 19 (18.3%) had intracytoplasmic sperm injection. Thirteen (12.5%) cases of cycle cancellation and 11 (11.7%) cases of mild‑to‑moderate ovarian hyperstimulation syndrome were recorded. The clinical pregnancy rate per cycle started was 39.4%. However, 9/41 (22%) resulted in spontaneous miscarriages and 32 (6 sets of twin, 25 singleton, and 1 high‑order multiple births) were successfully delivered, giving a live birth rate per cycle started of 30.8%. Pregnancy outcomes were not significantly affected by age of the women, types of infertility, and duration of infertility (P > 0.05). Conclusion: The outcomes of ART procedures in a resource‑limited country like ours are encouraging. This underscores the need to encourage ART in public tertiary institutions in Nigeria through the support of government and nongovernmental organizations for the benefit of infertile couples who were hitherto hopeless.Item Barriers to Contraceptive Uptake among Women of Reproductive Age in a Semi-Urban Community of Ekiti State, South west Nigeria.(Jimma University, Ethiopia, 2017) Durowade, K A.; Omokanye, Lukman O.; Elegbede, E.O.; Adetokunbo, S.; Olomofe, C.O.; Ajiboye, A.D.; Adeniyi, M.A.; Sanni, T.A.BACKGROUND: Globally, unplanned pregnancy and sexually transmitted infections (STIs) persist as a significant threat to women’s reproductive health. In Nigeria, despite huge resources committed to family planning programs by stakeholders, contraceptive use has been very low. This study aimed at unraveling the barriers to the use of modern contraceptives among women of reproductive age (15-49 years) in Ise-Ekiti community, Ekiti State, Southwest Nigeria. METHODS: This study was a cross sectional study among women aged 15-49 years. A multi-stage sampling technique was used in the recruitment of respondents from the community. An interviewer-administered questionnaire was used to collect data. Data were analyzed using SPSS version 15. RESULTS: Although contraceptive awareness among respondents was high 496(98.6%), only 254 of the 503 respondents were using modern contraceptive methods giving a Contraceptive Prevalence Rate (CPR) of 50.5%. Among those not using any form of contraceptives, some identifiable barriers to contraceptive use includes desire for more children, 62(39.5%), partner disapproval, 40(25.5%), and fear of side-effects, 23(14.6%). Factors associated with contraceptive uptake include marital status (p=0.028), educational level (p=0.041) and religion (p=0.043) with traditional worshippers having the least uptake. CONCLUSION: This study showed that awareness to modern forms of contraceptives does translate into use. The identified barriers to contraceptive uptake suggest the need to improve uptake of contraceptives through a community-based and culturally acceptable intervention as doing this will go a long way in addressing some of these barriers.Item Condom use among people living with HIV/AIDS attending Abejukolo General Hospital in Kogi State, North Central Nigeria(Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria, 2014) Salaudeen, A.G.; Musa, O.I.; Ojotule, A.; Yusuf, A.S.; Durowade, K A.Background: Condom programming is an integral component in a range of HIV/AIDS prevention strategies and with repeated sexual contact among HIV‑discordant couples, 98‑100% of those who used latex condoms correctly and consistently did not become infected. The objective of this study is to determine condom use among people living with HIV/AIDS (PLWHA). Methods: This is a cross‑sectional survey carried out among 231 PLWHA and receiving care and treatment at General Hospital Abejukolo in Kogi State, Nigeria. The research instrument was interviewer‑administered questionnaire. The data obtained were analysed using EPI‑INFO version 3.4.1 software and P-value of < 0.05 was significant for the study. Results: About three‑quarters (70.6%) of the respondents had ever used condom. Reasons given by respondents who did not use condom were: Desire for children (39.7%), and reduction of sexual pleasure (17.7%) and partner preference. More than half (56.0%) of the respondents with multiple partners did not use condom. About half 119 (51.5%) have used condom in the last sexual encounter. Gender, literacy level and disclosure of HIV status to partners significantly influence condom use during sexual intercourse. Conclusion: The poor uptake of condom among PLWHA underscores the need for government and other stakeholders in the management of HIV/AIDS to provide more enlightenment opportunities to address the gaps in condom use and disclosure of HIV status to patients.Item Controlled ovarian stimulation protocols in assisted conception: agonist versus antagonist in normal responders(African Journal of Infertility and Assisted Conception, 2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Saadu, L.O.; Biliaminu, S.A.; Durowade, K A.; Panti, Abubakar A.; Salaudeen, A.G.Item Determinants of Utilization of Assisted Reproductive Technology services in Ilorin, Nigeria(Regional Institute of Medical Sciences, Imphal, India, 2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Durowade, K A.; Raji, H.O.; Raji, S.T.; Biliaminu, S.A.; Salaudeen, A.G.Background: Infertility is the most important reproductive health and social issue confronting married couples in developing countries. Assisted Reproductive Technology (ART) offer a chance at parenthood to couples, who until recently would have had no hope of having a “biologically related” child. Aims and Objectives: This study aimed at determining the factors influencing the utilization of ART services at a public health facility in Ilorin, Nigeria. Materials and Methods: A cross‑sectional descriptive study of consecutively consenting infertile couples seen at the ART unit of the Department of Obstetrics and Gynaecology, University of Ilorin Teaching Hospital, Ilorin, between January 1, 2012, and December 31, 2015. Results: The patients aged 22–52 years with a mean age of 36.1 ± 6.6 years and mean duration of infertility of 7.3 ± 5.8 years. Majority (87.3%) was aware of ART services; only a few (15.6%) had ever used it. Most (63.3%) were of the opinion that ART is financially accessible. Reasons for nonutilization of ART were high cost (44.3%) and nonavailability (29.4%). Measures to enhance the utilization of ART were cost reduction (61.2%) and awareness creation (27.2%). Knowledge on ART practices showed that 56.7% were aware that the procedure could fail and 35.1% knew that it could address male infertility. Female partner age and parity had a significant influence on awareness and utilization of ART services. Conclusion: Awareness of ART services is high; however, utilization is abysmally low. Efforts should be made to make the procedure more affordable and accessible to the masses.Item Early sexual debut: prevalence and risk factors among secondary school students in Ido-ekiti, Ekiti state, South-West Nigeria.(College of Medicine, Makerere University, Kampala, Uganda, 2017) Durowade, K A.; Babatunde, O.A.; Omokanye, Lukman O.; Elegbede, O.E.; Ayodele, L.M.; Adewoye, K.R.; Adetokunbo, S.; Olomofe, C.O.; Fawole, A.A.; Adebola, O.E.; Olaniyan, T.O.Background: Early adolescent sexual activity remains a recurring problem with negative psychosocial and health outcomes. The age at sexual debut varies from place to place and among different individuals and is associated with varying factors. The aim was to determine the prevalence and risk factors of early sexual debut among secondary school students in Ido-Ekiti, South-West Nigeria. Methodology: This was a cross-sectional study. The respondents were selected using multi-stage sampling technique. Pre-tested, semi-structured, self-administered questionnaire was used to collect data. Data was analyzed using SPSS version 15. Results: More than two-thirds, 40(67.8%), had early sexual debut. The prevalence of early sexual debut was about 11%. The mean age of sexual debut was 13.10±2.82; the mean age for early sexual debutants was 11.68±1.98. The mean number of sexual partners was 2.44±1.99. Male gender, having friends who engaged in sexual activities had association with early sexual exposure (p<0.05). Alcohol intake had the strongest strength of association for early sexual debut among the students. Conclusion: The high prevalence of early sexual exposure among the students calls for urgent interventions to stem the trend. This will help to reduce the devastating negative psycho-social and health sequels.Item A five year review pattern of placenta previa in Ilorin, Nigeria(2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Salaudeen, A.G.; Ajiboye, A.D.; Durowade, K A.Background: Placenta previa, a major cause of obstetric hemorrhage, is potentially life-threatening to the mother and frequently results in high perinatal morbidity and mortality. Methodology: This is a retrospective study of all cases of placenta previa managed at the University of Ilorin Teaching Hospital over a 5-year from January 2011 to December 2015. A pro forma template was used to harvest information from case notes of patients involved in the study. Results: There were a total of 10,250 deliveries over the 5-year study and 164 cases of placenta previa were managed during this period; giving an incidence of 1.6% of the total deliveries. Of these patients, 65.9% were unbooked while 34.1% were booked. 110 (67%) were above 30 years of age and 51.2% were grand multiparous women. The majority (81.7%) of the patients belonged to the low socioeconomic class. Painless vaginal bleeding (62.2%), intrapartum hemorrhage (22.6%), and abnormal lie presentation (8.5%) were the most common mode of presentation. Vaginal delivery occurred in (29.3%) of patients while 70. 7% were delivered through cesarean section. There was a significant association between patients’ age, parity, booking status, and types of placenta previa (P < 0.05). Similarly, there was a significant association between gestational age at delivery, mode of delivery, intraoperative blood loss, and birth weight at delivery and types of placenta previa (P < 0.05). Perinatal mortality was 12.2%, 15.6% of babies had severe birth asphyxia, and there was no maternal mortality. Conclusion: From this study, the risk factors for placenta previa are advanced maternal age above 35 years, grand multiparity, and booking status. Early recognition, appropriate referral of these patients and availability of ultrasound facilities, blood transfusion facilities, improvement in neonatal facilities and trained personnel will go a long way in reducing the perinatal mortality from placenta previa.Item Knowledge and prevalence of risk factors for arterial hypertension and blood pressure pattern among bankers and traffic wardens in Ilorin, Nigeria(College of Medicine, Makerere University, Kampala, Uganda, 2014) Salaudeen, A.G.; Musa, I.O.; Babatunde, O.A.; Atoyebi, O.A.; Durowade, K A.; Omokanye, Lukman O.Background: High job strain, mental stress, sedentary lifestyle, increase in BMI are among the factors associated with significantly higher incidence of hypertension. The job of bank employees is both sedentary in nature and accompanies high mental stress. The aim of this study is to assess the level of knowledge of risk factors among respondents and to compare the blood pressure pattern of bankers and traffic wardens. Methodology: The study design is a descriptive cross-sectional conducted among bankers and traffic wardens in Ilorin to determine the pattern and knowledge of blood pressure. Self-administered questionnaires, weighing scale (Omron Digital scale), stadiometer and sphygmomanometer were used as the research instruments. Simple random sampling was used to select respondents involved in the study. Results: The prevalence of hypertension in this study was 34.4% in bankers and 22.2% in traffic wardens. The risk factors the bankers commonly had knowledge of are alcohol, obesity, high salt intake, certain drugs, stress, emotional problems and family history while the traffic wardens commonly had knowledge of all these in addition to cigarette smoking. Also, more bankers (32.2%) than traffic wardens (13.3%) were smoking cigarette and more of these cigarette smokers that are bankers (17.8%) had elevated blood pressure compared to the traffic wardens (3.3%). Conclusion: Workers in the banking industry as well as traffic wardens should be better educated about the risk factors of hypertension and bankers should be encouraged to create time for exercise.Item Mayer – Rokitansky Syndrome Type 1 With Karyotype XY Variant: A Case Study(College of Health Sciences, University of Ilorin, 2015) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Durowade, K A.; Panti, Abubakar A.; Salaudeen, A.G.; Adewara, E.O.Item Pattern and predictor of contraception uptake among women in Olufadi community Ilorin- south Local Government Area, Kwara State, Nigeria(College of Health Sciences, Delta state University, Abraka, Nigeria, 2013) Durowade, K A.; Salaudeen, A.G; Elegbede, O.E.; Babatunde, O.A.; Fasiku, M.M.; Adebola, O.E.; Omokanye, Lukman O.; Fawowe, A.A.Item Study on comparison of serum levels of calcium, magnesium and uric acid in mild preeclamptics, severe preeclamptic and normal pregnant women in Ilorin, Nigeria(Centre for Reproductive and Developmental Programming, 2015) Omokanye, Lukman O.; Abdulkareem, N.; Olatinwo, Abdulwaheed O.; Abdul, I.F.; Durowade, K A.; Biliaminu, S.A.Background: Preeclampsia is pregnancy-specifi c syndrome and contributes about 15% of maternal mortality and preterm deliveries. Objective: To compare the serum levels of calcium, magnesium, and uric acid in mild preeclamptics, severe preeclamptics, and normal pregnant women. Materials and Methods: A cross-sectional study conducted at the Department of Obstetrics and Gynaecology of the University of Ilorin Teaching Hospital (UITH) Ilorin. The data were collected from 64 normal pregnant women, 64 mild preeclamptic women, and 64 severe preeclamptic women who presented at the Department of Obstetrics and Gynaecology, UITH between June 2013 and January 2014. The data were analyzed using analysis of variance. Results: The mean serum calcium concentration in severe preeclamptics and mild preeclamptics was signifi cantly reduced (1.75 ± 0.63 mmol/L and 1.90 ± 0.44 mmol/L vs. 2.28 ± 0.24 mmol/L, P = 0.00) compared with serum calcium concentration in normal pregnant controls. The serum magnesium concentration among severe preeclamptics was also signifi cantly reduced (0.84 ± 0.44 mmol/L versus 1.05 ± 0.28 mmol/L, P = 0.00) compared with serum magnesium among normal pregnant controls. However, there was no statistically signifi cant difference in serum magnesium concentration between mild preeclamptic women and normal pregnant women (1.01 ± 0.26 mmol/L vs. 1.05 ± 0.28 mmol/L). The serum uric acid concentration was signifi cantly elevated among both mild and severe preeclamptic women compared with the serum uric acid concentration among normal pregnant control (0.89 ± 0.63 mmol/L and 1.25 ± 0.68 mmo/L vs. 0.21 ± 0.19 mmol/L). Conclusions: It is concluded that while reduced serum calcium levels and elevated serum uric acid levels correlate with etiopathogenesis of preeclampsia, reduced serum magnesium correlates with severity of preeclampsia.Item Successful Rescue Cerclage at Advanced Cervical Dilatation in the Second Trimester(Yenepoya University, 2016) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Durowade, K A.; Biliaminu, S.A.Cervical cerclage has been used in the management of cervical insufficiency for several decades, yet the indications are uncertain and benefits questionable. It remains a controversial intervention. We present a case of cervical incompetence in a 33‑year‑old Gravida 5 Para 0+4 woman who had an emergency cervical cerclage at 18 weeks gestation and subsequently delivered of a live male infant at 29 weeks gestation following preterm premature rupture of fetal membrane.Item Tubal factor infertility: Hysterosalpingography and Laparoscopic evaluation in Ilorin, Nigeria(College of Health Sciences, Delta state University, Abraka, Nigeria, 2017) Omokanye, Lukman O.; Olatinwo, Abdulwaheed O.; Ibrahim, S.; Saadu, L.; Durowade, K A.; Panti, Abubakar A.Objectives: To compare diagnostic accuracy of laparoscopy and HSG in the evaluation of tubal patency among infertile women. Materials and Methods: A cross-sectional prospective study of infertile women who underwent HSG st st and laparoscopy for tubal patency between 1 January 2011 and 31 December 2015. Results: Ninety-seven (97) eligible patients were included in the study. The patients were aged 21-50 years with a mean age of 33 ± 6.6 years. Majority (79.4%) were nulliparous. Most (63.9%) belong to middle social class. Fifty (51.5%) had primary infertility while (48.5%) had secondary infertility. Their duration of infertility ranges from 1-33 years (5.6 ± 5.5). HSG revealed bilateral tubal blockade in 23 (23.7%), bilateral patent tubes in 38 (39.2%) and unilateral patent tube in 36 (37.1%) while laparoscopy showed bilateral tubal blockade in 18 (18.6%), bilateral patent tubes in 51 (52.6%) and unilateral patent tube in 28 (28.8%) respectively. There was significant difference between HSG and laparoscopic findings on tubal status determination (p <0.05). Laparoscopy revealed other tubal and non-tubal pelvic findings not evident on HSG. The sensitivity of HSG was 100%, specificity was 93.7%, and the positive predictive value was 78.3%, with a negative predictive value of 100%. Conclusion: HSG and laparoscopy are of diagnostic importance in the evaluation of tubal status; however, laparoscopy is superior most especially in the detection of other tubal and non tubal pathologies which could be responsible for infertility; thus both tests are complimentary. Tubal Factor Infertility: Hysterosalpingography and Laparoscopic Evaluation in Ilorin, Nigeria.