Browsing by Author "Ayinla, M.T.,"

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    Androgenic effects of aqueous extract of moringa oleifera in male Wistar rats.
    (School of Medicine and Health Sciences, University of Papua, New Guinea., 2022) Ayinla, M.T.,; Sikirulai, M.A.,; Ayinde, T.O., .; Ojulari, L.S.,; Owoyele, V.B.,; Asuku, A.O.,; Adebisi, R.O.,; Badmus, O.A.,; Murthy, R.K.
    Androgenic effects of Aqueous Seed-extract of Moringa oleifera (ASMO) in male Wistar rats were investigated. Eighteen (18) male Wistar rats weighing 200-240g were used for this study. The rats were divided into three (3) groups: Control (Group 1) that received 10 ml/kg of normal saline, Group 2: received low dose of ASMO (200mg/kg), and Group 3: received high dose of ASMO (500mg/kg). The animals were treated for twenty-eight days. On the 29th day, the rats were sacrificed and the testes were carefully removed for semen and biochemical analysis. Body weight, reproductive and vital organ weights were determined. Sperm parameters (motility, morphology, count and viability), tissue testosterone, luteinizing hormone (LH), Malondialdehyde (MDA) and Catalase were also determined using standard methods. Data were analysed using one-way ANOVA followed by Duncan new multiple range post hoc test. The result showed ASMO significantly increased (p<0.05) the final body weight, weight of reproductive and vital organs. Moreover, 200mg/kg body weight dose of ASMO significantly increased (p<0.05) the sperm parameters but 500mg/kg body weight dose significantly decreased it. ASMO also caused a significant dose dependent increase (p<0.05) in testosterone and catalase level but a significant decrease (p<0.05) in MDA and LH level compared with the control. In conclusion, this study revealed that ASMO has androgenic effects in male rats and thus provides a basis for the traditional use of Moringa oleifera in the management of male sexual disorders
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    Effect of Ice Cooling Jacket on Cardiovascular Responses to Treadmill Exercise in Untrained adults.
    (The Library and Publications Committee, University of Ilorin, 2015) Niyi-Odumosu, F.A; Esu, K.D.,; Ayinla, M.T.,; Gwadabe, S.M.; Dominic, O.L.
    Hyperthermia has been shown to be a limiting factor to endurance exercise performance while pre-cooling combats the debilitating effect of heat stress induced fatigue. Most studies demonstrated attenuated heart rate response during endurance exercise after pre-cooling, none of these examined blood pressure changes. Therefore, the objective of this study is to recognize, quantify, and compare changes that may occur in blood pressures and heart rate after pre-cooling (wearing of ice jacket) following treadmill exercise. Twelve (n=12) healthy nonathletic young male adults volunteered after obtaining written consent. Mean ± S.E.M age, weight, height and B.M.I were 22.0±0.8 years, 60±3.0 kg, 1.7±0.2 m, and 21.0±1.0 kg/m2. Day 1, participants performed treadmill exercise to exhaustion (Bruce protocol). Two readings of blood pressures and heart rates were taken before, at exhaustion and five minutes into recovery. Day 2, participants wore ice jackets for about 30 minutes before the exercise. There was a significant reduction (p<0.05) in the heart rate at exhaustion from 101.3 ± 6.5 to 98.1 ± 5.7 and during recovery from 95.3 ± 5.0 to 79.4 ± 3.6 with no significant change in the blood pressures after pre-cooling. Findings are in support of previous studies and may suggest that wearing of ice-cooling jacket attenuates heart rate with no significant change in the blood pressures following isotonic treadmill exercise in untrained young male adults.
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    Low glycaemic index foods, a better option for pre-exercise meals.
    (College of Medicine, Ambrose Alli University,, 2017) Ojulari, L.S.,; Ayinde, T.O.,; Kadir, R.E.,; Biliaminu, S.A.,; Nafiu, A.B.,; Ayinla, M.T.,; Jimoh-Abdulghaffaar, H.O.,; Imam-Fulani, A.O.; Fatai, R.A.