Browsing by Author "Akande, T.M"

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    Beta- Thalassaemia Trait Screening Using Capillary Electrophoresis Among Voluntary Blood Donor in North Central Nigeria
    (College of Health Sciences, University of Ilorin, Ilorin, Nigeria., 2021-01) Durotoye, I A.; Salaudeen, AG; Sanni, E.O; Babatunde, A.S; Adekunle, D.K; Akande, T.M; Olawumi, H.O.; Musa, O.I
    Beta-thalassaemia(â-thalassaemia) carriers exists in malaria endemic zones of sub-Sahara Africa including Nigeria. Studies on â-thalassaemia in Nigeria are few in the literature. The high variation in the prevalence of â-thalassaemia in Nigeria as reported in previous studies raises concern. Newer screening techniques such as capillary electrophoresis is now being used in clinical laboratories. This study screened for â-Thalassaemia carriers among voluntary blood donors using capillary electrophoresis. A descriptive cross-sectional study was conducted among 100 voluntary blood donors among students of Kwara State Polytechnic, Ilorin, Nigeria with age range of 18-34years. The participants consist of 55 males (55%) and 45 females (45%). Capillary electrophoresis using the Minicap system was used for determining the Haemoglobin A2 and F quantification in alkaline buffer (PH 9.4). Data analysis was done using SPSS and p-value<0.05 was taken as the level of significance The mean age of the participants was 22.23 ± 3.3 SD years(mean age of males 23±3.3 and females 20±2.8) The mean HbA2 among the participants was 3.49± 0.9SD (Range 0.8-5.30%). The mean HbF was 1.43± 0.57SD (Range 0.80-2.50%). Three (3/100) of the subjects had both elevated HbA2 > 3.9% and HbF >1%, giving a prevalence of 3% for â thalassaemia >1%, giving a prevalence of 3% for â thalassaemia carriers among blood donors in this study. The prevalence of â thalassaemia carrier was 3% in our study and found among female folks. Data from this study will be useful in raising awareness and genetic counseling especially among female blood donors.
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    Comparative Assessment of Health Workers Performance and The Per-formance Factors at Primary, Secondary and Tertiary Hospitals in Kwara State, Nigeria
    (The Tropical Journal of Health Sciences. CHS Unilorin, 2018) Saka, M.J; Akande, T.M; Olarinoye, A.O; Raji, H.O; Saka, A.O
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    Determinants of voluntary blood donation among adults in communities of north central region of Nigeria
    (Osun State University, 2019-06-30) Salaudeen, AG; Durowade, K.A; Durotoye, I A.; Ahmed, A.; Sanni, E.O; M, O.I; Akande, T.M
    Objective: The collection of blood from voluntary, non-remunerated blood donors is an important measure for ensuring the safety, quality, availability and accessibility of blood. The study assessed factors affecting voluntary blood donation in North-central zone, Nigeria. Methods: The study design was descriptive cross-sectional, data was collected using a pre-tested interviewer administered questionnaire from 3104 respondents using multistage sampling technique. Data was analyzed using EPI INFO computer software package (version 3.5.3). Level of significance was pre-determined at p-value < 0.05 at a confidence level of 95%. Results: Respondents with good knowledge of voluntary blood donation had better practice of voluntary blood donation. Younger age groups were 8 times more likely to donate blood voluntarily than older respondents. Yoruba ethnic groups are 1.5 times more likely to donate blood than other ethnic groups. Conclusion: For Nigeria and other developing countries at large to achieve 100% voluntary blood donation drive by year 2020, it is critical to change the blood donation culture from replacement to that of volunteerism through more effective communication and mobilization of donors. These efforts must be rendered more methodical and accomplished through a wider range of strategies.
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    Determination of Normal and Variant Hemoglobin using Capillary Electrophoresis among Voluntary Blood Donors in North Central Nigeria: Implications on Blood Transfusion Services
    (Faculty of Medicine and Health Sciences, Omdurman Islamic University, Sudan, 2021-03-31) Durotoye, I A.; Salaudeen, AG; Sanni, E.O; Babatunde, A.S; Durowade, A.K; Olawumi, H.O.; Akande, T.M; Musa, O.I
    Background: Voluntary non-remunerated blood donation is a strategy adopted by World Health Organization aimed at ensuring safety and adequacy of blood supply. Sub-Saharan Africa has a high prevalence of hemoglobin disorders and therefore needs to adopt stringent measures in donor selection to ensure safety for the recipient of blood transfusion. This study aimed to analyze normal and variant hemoglobin among voluntary blood donors. Methods: In this descriptive cross-sectional study, 100 prospective blood donors including 55 (55%) males and 45 (45%) females, aged 18–34 years were recruited. Capillary electrophoresis using the Minicap system was used for determining the hemoglobin variants in alkaline buffer (PH 9.4). Data analysis was done using SPSS version 20 and p-value < 0.05 was considered as the level of significance Results: The mean age of the participants was 22.23 ± 3.3 SD years. The proportion of participants with genotype AA was 67 (67%), those with AS were 17 (22 %), while those with AC were 11 (11 %). While Hb A ≥ 90% was noted in 67 (67%) blood donors, Hb S was seen in 22 (22%) and Hb A2 > 3.5% in 57 (57%). Hb F > 2% was observed in 3% of the studied participants Conclusion: Variant hemoglobin is common among blood donors and this should be taken into consideration whenever blood is being crossmatched for recipients of blood transfusion. Data from this study will be useful in raising awareness and genetic counseling.
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    Marketing Anti Malaria Drugs by CTC-MS in Kwara State Nigeria
    (Ilorin Journal of Marketing., 2015) Saka, M. J; Akande, T.M; Saka, A.O; Musa, O.I; Abdulrahim, A
    Abstract igeria recently changed her antimalarial treatment policy from monotheraphy single Nbased to artemisinin-based combination therapy (ACT). Close to Community Medicine Sellers (CTC-MS) were defined to include all commercial retailers supplying malaria drugs. The study examines implementation of National malaria drug policy by Close to Community Medicine Sellers (CTC-MS) in Kwara state Nigeria. It was a descriptive cross sectional study, multi stage sampling techniques was adopted and interviewer administered questionnaires was used to collect data. EPI-INFO software statistical package was used to analysis. Despite high level of awareness (53.9%) of new treatment guidelines for malaria, ninety (43.0%) of the CTC- MS correctly differentiate between artesunate monotherapy and artemisinin-based combination therapy (ACT).Only 96 (46.6%) respondents sold artemisinin-based combination therapy (ACT) in the new policy for the treatment of malaria. Majority CTC-MS sold Chloroquine (84.0%) and Qunine (64.1%) respectively, (75.2%) of the respondents agreed to sell any form of monotherapy for the treatment of malaria. Due to non-availability (47.1%), competition from other providers (35.3%) and high cost (17.6%). Age, educational level, years of practice and type of training significantly affected response to the implementation of new malaria guideline. Mono therapy still considered to be adequate for treatment of malaria, there is increased marketing of antimalaria monotheraphy drugs and advised to consumers to purchase Artesunate monotheraphy for the treatment of malaria. Non-availability and high cost of ACT drugs are some of the factors responsible for the sales of monototheraphy anti malaria drugs. It is recommended that special interventions such as trainings, continuous professional medical education on new anti–malaria drugs and government to withdraw non-ACT antimalarials from the market. In addition age limit, years of practices and source of trainings should be considered by the formal or informal association of CTC-MS prior to approval to join the market for sales of anti-malaria drugs therapy.
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    Prevalence and Predictors of Helminthic Infections among Pupils in a Public Primary School on a North-Central City of Nigeria
    (JOURNAL OF COMMUNITY MEDICINE AND PRIMARY HEALTH CARE, 2014-09) Ameen H.A; Salaudeen A.G; Bolarinwa O.A; Uthman M.M.B; Musa O.I; Akande, T.M
    Abstract Background: The prevalence and intensity of helminthiasis are highest in children aged 5-15 years where it accounts for 12% of the total disease burden and 20 % of disability adjusted life years (DALYs) lost among this age group. This study therefore, aims to determine the prevalence and predictors of helminthiasis among pupils in a public primary school in a metropolitan city in north-central Nigeria. Methodology: A descriptive cross-sectional study was carried out between June and November 2010 among pupils registered for the academic year in Okelele Community Ilorin, Nigeria, using a multi- stage sampling technique in 3-stages to recruit 300 participants. A semi-structured, interviewer-administered questionnaire was used to collect quantitative data from respondents and their stool samples were also collected for microscopic examination. Findings The prevalence of helminthiasis was relatively high (32.0%) with a peak prevalence in the 9-12 years old age group. No statistically significant associations were found between prevalence of ascariasis and age, sex, maternal educational backgrounds and maternal occupational status (p > 0.05). Similarly, no statistically significant associations were found between prevalence of ascariasis and hygiene habits of pupils (p > 0.05). Conclusion: Soil-transmitted helminthic infections are still pervasive among school- age children. Implementation of school health service programme will go a long way to improving the environmental, personal and food hygiene habits of pupils thereby reducing helminthic infections among school children.
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    Traditional eye pencil: A rural- urban comparison of pattern of uptake and association with glaucoma among adults in selected communities of North Central Nigeria
    (African Health Research Organization, 2017) Durowade, K.A; Salaudeen, A.G.; Musa, O.I; Olokoba, L.B; Omokanye, L.O; Akande, T.M