Browsing by Author "Akanbi, K."

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    Hepatitis B surface antigenaemia and risk factors of transmission among apparently healthy students of University of Ilorin, Ilorin-Nigeria
    (College of Natural and Applied Science, University of Port Harcourt, Port Harcourt, Nigeria, 2012) Udeze, A.O.; Aliyu, A.S.; Kolawole, O.M.; Okonko, I.O.; Sule, W.F.; Akanbi, K.
    This study aimed at determining the prevalence of Hepatitis B surface antigenaemia among first year students of University of Ilorin, Ilorin Nigeria. A total of 200 students (119 males and 81 females: ages 16 to 40 years), who consented voluntarily after thorough explanation of the purpose of the study, were selected. The sera of the participants were tested for the presence of HBsAg by parallel diagnostic method using Diaspot® HBsAg test kit and Smart CheckTM HBsAg device. Of the 200 samples tested, 18 (9.0%) were HBsAg positive. The result also showed that 13 (10.9%) out of the 119 males were positive, while 5 (6.2%) out of the 81 females were positive. Analysis of the results by age groups showed that subjects ≤20 years had a prevalence of 9.8%, subjects of age range 21-30 years had a prevalence of 8.1% while subjects of age range 31-40 years had zero prevalence. Analysis of the results according to the risk factors of transmission showed that subjects who reported circumcision only had a prevalence of 7.4%, while subjects who reported history of medical operation and blood transfusion had a prevalence of 10.0%. Among subjects who reported HBV vaccination only, prevalence of 8.3% was recorded, while 12.5% prevalence was recorded for subjects who reported a combination of circumcision, medical operation and blood transfusion. This study however confirmed the presence of Hepatitis B surface antigenaemia among apparently healthy first year students of the University of Ilorin. General surveillance, mass immunization and public health education to stop the spread of the infection on campus and indeed the whole society is advocated.
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    Serosurvey of Herpes simplex virus type-2 infection among HIV infected individuals accessing a secondary health care facility in Kwara State, North Central Nigeria.
    (Faculties of Life and Physical Sciences, University of Ilorin, 2017) Odebisi-Omokanye, M.B.; Udeze, A.O.; Akanbi, K.; Jimoh, N.K.; Imam, M.A.
    Herpes Simplex Virus type 2 (HSV-2) is a commonly opportunistic infection among HIV seropositive subjects and acts synergistically with HIV to accelerate disease progression. This is across sectional, Hospital-based study designed to determine the prevalence of HSV-2 IgM and IgG antibodies among HIV-1infected individuals accessing the HAART Clinic of General Hospital Offa, Kwara State Nigeria. Blood samples were collected from consenting 276 (age range 11-70; mean age of 36.8 years) HIV-1 infected individuals after collecting pertinent socio-demographic data using questionnaires. The blood was separated into plasma and packed cells. The former was tested for the presence of anti- HSV-2 IgM and IgG using ELISA test kits from Diagnostic Automation INC., USA. Data were analyzed using Chi square test with SPSS version 21 software and the level of significance was determined to be P < 0.05.Out of 276 samples tested, 116 (42.0%) and 39 (14.1%) were respectively positive for HSV-2 IgG and IgM antibodies. These respectively represent latent and active HSV-2 infections. Gender, occupation and clinical state of the subjects were the main correlates of IgM serpositivity while gender, occupation, marital status and CD4+ count correlates with IgG seropositivity. The prevalence of anti-HSV-2 IgM and IgG antibodies in this cohort of HIV-infected individuals is high. There is therefore the need for routine test for HSV-2 infection among HIV infected individuals to determine the extent of infection and proper management especially the active infections