Browsing by Author "Adesokan A.A"

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    Cigarette Smoking and Thyroid Hormone Levels in Nigerian Smokers
    (African Journal of Tropical Medicine and Biomedical Research March, 2017-03) Adunmo G.O; Adesokan A.A; Akanji, M.A ,; Biliaminu S.A ,; AbdulAzeez, I. M ,; AdunmoE.O
    ABSTRACT 4 Background: Cigarette smoking has been linked with thyroid disorders with inconsistent result with some studies linking cigarette smoking to increased thyroid hormone level and others to decreased thyroid hormone levels. Thus, the aim of this study is to further evaluate the effect of cigarette smoking on thyroid hormone pattern in non-alcoholic smokers in North Eastern Nigeria Methodology: Free Triodothyronine(fT3), Free thyroxine (fT4) and their regulatory hormone, Thyrotrophin stimulating Hormone(TSH) were evaluated in male current smokers (n=140), ex-smokers (n=12) and non-smokers (n=84). The current smokers were also categorized based on daily cigarette consumption (Light (<5 sticks/Day), Moderate (6-10 sticks/day) and Heavy (>10 sticks/day)) and duration of smoking (Short (5-10 years), Medium (11-20 years) and Long (>20 years). A structured questionnaire was used to get information on their clinical history, daily cigarette consumption and duration of smoking. Results: fT3 and fT4 were found to be significantly elevated in smokers (p<0.05) with no significant change in TSH level(p>0.05). No significant difference was observed between ex-smokers and non smokers. Conclusion: The results suggests a direct stimulatory effect of cigarette smoking on thyroid gland and thus at risk of hyperthyroidism, though this effect could be reversed by quitting smoking. Key words: Cigarette smoking; Hyperthyroidism; Free Thyroxine; Free Ttriiodothyronine; Thyroid hormones; Thyroid Stimulating Hormone. methods.
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    Effect of Chronic Cigarette Smoking on lipid profile – A Pilot study in North-Eastern Nigeria.
    (Sokoto Journal of Medical Laboratory Science, 2016) Adunmo G.O; Adesokan A.A; Biliaminu S.A,; Abdulazeez, I.M; Adunmo E.O
    Abstract Cigarette smoking is a major risk factor of atherosclerosis and coronary artery disease. It has been linked with alterations in lipid profile level but which fraction of lipids profile is affected by cigarette smoking remains controversial. In this study we evaluated the lipids profile among smokers in North-Eastern Nigerian. Total Cholesterol (Tc), High Density Lipoprotein Cholesterol (HDL-c) and Triglycerides (TG) were determined colometrically but Low Density Lipoprotein Cholesterol (LDL-c) was calculated. A total of One hundred and forty (140) current smokers, Twelve (12) Ex-smokers and Eighty four (84) controls were recruited. The current smokers were also categorized based on daily cigarette consumption; Light (<5 sticks/Day), Moderate (6-10 sticks/day) and Heavy (>10 sticks/day), and duration of smoking; Short (5-10 years ), Medium (11-20years) and Long (>20 years). Clinical history, daily cigarette consumption and duration of smoking were obtained from a semi–structured questionnaire. TC, LDL-c, and TG were all significantly elevated in current smokers compared with control (p<0.05) with a significant decrease in HDL level (p<0.05). They all correlated with duration and quantity of daily cigarette consumption. There was no significant difference between ex smokers and control, except for the significant increase in TG level observed. The results indicated an increased risk of dyslipidaemia in cigarette smokers which is pro-atherogenic and can potentially put smokers at a greater risk of cardiovascular diseases. Key words: Atherogenic indices, Atherosclerosis, Cholesterol; Lipids; Cigarette smoking; Cardiovascular Disease.