Chemical constituents and antiproferative properties of Turraea vogelli Hook. f. ex. Benth leaves
| dc.contributor.author | Hamid, Abdulmumeen Amao | |
| dc.contributor.author | Aiyelaagbe, O. Olapeju | |
| dc.contributor.author | Oguntoye, Stephen O. | |
| dc.contributor.author | Negi, Arvind Singh | |
| dc.contributor.author | Zubair, Marili F. | |
| dc.date.accessioned | 2026-05-04T10:34:09Z | |
| dc.date.available | 2026-05-04T10:34:09Z | |
| dc.date.issued | 2015-06-01 | |
| dc.description | N/A | |
| dc.description.abstract | Ethyl acetate and methanol extracts of Turraea vogelli leaves exhibited cytotoxic activity on leukaemia carcinoma K562 with IC50 values 85.00 and 85.22 ug/mL respectively. Isolation of the extracts afforded tetradec-7-enoic acid (1), pentadec-1-ene (2), ethyl tridec-7-enoate (3), Beta-sitosterol (4) and stigmasterol (5). The structures of these compounds were characterised by IR, 1D and 2D NMR and Mass Spectroscopy, and supported with literature data. Compounds 1 and 4 exhibited antiproliferative activity against K562 tumor cell lines with 1C50 of 57.27 and 27.56 ug/mL respectively. All isolated compounds exhibited low cytotoxicity against WRL and MCF - 7 tumor cell lines | |
| dc.description.sponsorship | TWAS-CSIR Postgraduate fellowship, and CSIR-Central Institute of Medicinal and Aromatic Plants (CSIR-CIMAP). | |
| dc.identifier.issn | 2141-3819 | |
| dc.identifier.uri | https://uilspace.unilorin.edu.ng/handle/123456789/17949 | |
| dc.language.iso | en | |
| dc.publisher | The Library and Publications Committee, University of Ilorin, Nigeria | |
| dc.subject | Turraea vogelli | |
| dc.subject | antiproliferative activity | |
| dc.subject | Beta-sitosterol | |
| dc.subject | stigmasterol | |
| dc.subject | ethyl tridec-7-enoate | |
| dc.title | Chemical constituents and antiproferative properties of Turraea vogelli Hook. f. ex. Benth leaves | |
| dc.title.alternative | 2015 | |
| dc.type | Article |