A new sesquiterpene, prosoterpene, from Prosopis africana (Guill. & Perr.) Taub.

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dc.contributor.authorAli, R.
dc.contributor.authorSalawu, K.M.
dc.contributor.authorAamer, M.
dc.contributor.authorJahan, H.
dc.contributor.authorTufail, P.
dc.contributor.authorIrshad, R.
dc.contributor.authorKhan, F.A.
dc.contributor.authorSener, B.
dc.contributor.authorChoudhary, M.I.
dc.contributor.authorWang, Y
dc.date.accessioned2023-03-31T08:01:39Z
dc.date.available2023-03-31T08:01:39Z
dc.date.issued2022
dc.description.abstractA new sesquiterpene (Prosoterpene, 1) and eleven reported compounds (2–12) of several classes, such as flavonoids, alkaloids, phenolic acids, and long-chain alcohols, were isolated from the BuOH extract of Prosopis africana (Guill. & Perr.) Taub. Compounds 2–10 were reported for the first time from this plant. Isomers 11 and 12 were separated for the first time. Extensive spectroscopic techniques and literature comparisons were used to characterise their structures. Furthermore, compounds 3, 5–8, and 10–12 were performed for anti-glycation and cytotoxicity activities. Compound 3 (quercetin-3-O-a-L-rhamnoside) exhibited moderate anti-glycation activity. All tested compounds were noncytotoxic against MCF-7 (breast cancer), NCI-H460 (lung cancer), Hela (cervical cancer), and BJ (normal human fibroblast) cell lines.en_US
dc.description.sponsorshipThe authors are very grateful for the support from Higher Education Commission, Pakistan for support to the NRPU 2021 # 17603. We acknowledge the National Administration of Traditional Chinese Medicine, P. R. China, and Health & Population Welfare Department, Government of Sindh, Pakistan, for the support to ‘Sino-Pakistan Cooperation Center on Traditional Chinese Medicine (No. GZYYGJ2020023)’ located at the International Center for Chemical and Biological Sciences, University of Karachi, Pakistan. Higher Education Commission (HEC), Pakistan.en_US
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/20.500.12484/8952
dc.language.isoenen_US
dc.publisherNatural Product Researchen_US
dc.subjectProsopis africana; sesquiterpene; prosoterpene; quercetin-3-O-a-Lrhamnoside; anti-glycationen_US
dc.titleA new sesquiterpene, prosoterpene, from Prosopis africana (Guill. & Perr.) Taub.en_US
dc.typeArticleen_US

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