Thaumatococcus danielli leaves; It’s Chemical composition, antioxidant and antimicrobial activities.
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Date
2017
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Journal ISSN
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Faculty of Science Obafemi Awolowo University, Ile-Ife, Nigeria.
Abstract
The preliminary phytochemical investigation of n-hexane, ethyl acetate and methanol extracts of Thaumatococcus
daniellii leaves revealed the presence of fats and oils, terpenoids, flavonoids, steroids and glycosides. The
antimicrobial tests against some strains of bacteria and fungi showed inhibitions at moderate to high
concentrations. Methanol extract of the plant exhibited low 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical
scavenging activity with IC of 615.14 μg/ml. Gas chromatography-mass spectrometry (GC-MS) 50
characterization of n-hexane, ethylacetate and methanol extracts of T. daniellii leaves identified , thirteen and
fifteen compounds, with tetracontane (28.76%) and L-ascorbic acid (15.07%); hexadecanoic acid (21.62%) and
γ-sitosterol (11.06%); and naphthalene-1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-
,[1R(1.alpha.,7.beta.,8a.alpha.] (26.90%) and hexadecanoic acid (12.60%) being the major compounds
respectively. The GC-MS analysis revealed various peaks of bioactive compounds of which the antioxidant and
antimicrobial activities of the plant have been attributed to the prominent compounds in synergy with all the
other compounds present in smaller quantities in the extracts.