Serum zinc levels as a predictor of clinical features and outcome of paediatric acute lower respiratory infections in Nigeria.

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dc.contributor.authorIbraheem, Rasheedat
dc.contributor.authorJohnson, 'Wahab
dc.contributor.authorAbdulkarim, Aishatu
dc.contributor.authorAbdulkadir, Mohammed
dc.contributor.authorOladele, Damilola
dc.contributor.authorBiliaminu, Sikiru
dc.date.accessioned2018-06-05T08:29:53Z
dc.date.available2018-06-05T08:29:53Z
dc.date.issued2013
dc.description.abstractBackground: Malnutrition, especially macronutrient deficiency, has been shown to be interrelated with ALRI-related morbidity and mortality. However the import of zinc deficiency has only recently become the focus of research attention. Objective: The current study was carried out in Ilorin, Kwara State, Nigeria to determine the relationship between serum zinc levels, clinical features and outcome in hospitalized children with acute lower respiratory infections (ALRI). Method: A descriptive cross-sectional hospital-based study involving 120 children aged two months to five years with ALRI. Socio-demographic, clinical and laboratory data were obtained. The serum zinc was analyzed with a Jenway™ spectrophotometer after initial preparation with the QuantiChrom™ zinc assay kit. Results: Children with tachypnoea and crepitations had significantly lower mean serum zinc levels compared to the corresponding values in those without these features (each p<0.05). Significantly higher mean serum zinc level was recorded in children with grunting respiration compared with those without grunting (p=0.028). Age-related tachypnoea, grunting, and crepitations remained significant (each p<0.05) following a linear regression analysis. The mean serum zinc level in children with multiple complications was significantly lower than the corresponding level recorded in children who had one complication, p=0.020. No significant difference was found between the mean serum zinc level of the children who were discharged compared with the corresponding level recorded in those that died, p=0.589. Conclusion: The presence of crepitations had the strongest clinical association with a low serum zinc level. Children managed for ALRI would benefit from post-treatment zinc supplements and appropriate zinc-rich sources of food at discharge.en_US
dc.identifier.citationIbraheem, R.M., Johnson, ‘W.B.R., Abdulkarim, A.A., Abdulkadir, M.B., Oladele, D. & Biliaminu S.A. (2013): Serum zinc levels as a predictor of clinical features and outcome of paediatric acute lower respiratory infections in Nigeria. Nigerian Journal of Paediatrics. 40(4); 200-205en_US
dc.identifier.urihttps://www.ajol.info/index.php/njp/article/view/94315
dc.identifier.urihttp://hdl.handle.net/123456789/362
dc.language.isoenen_US
dc.publisherPeadiatric Association of Nigeriaen_US
dc.subjectChildrenen_US
dc.subjectZincen_US
dc.subjectRespiratory infectionsen_US
dc.titleSerum zinc levels as a predictor of clinical features and outcome of paediatric acute lower respiratory infections in Nigeria.en_US
dc.typeArticleen_US

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