Chelation, Characterization and Antimicrobial screening of Mixed Isoniazid - Vitamin C complexes

Simple item page
dc.contributor.authorBamigboye, M. O.
dc.contributor.authorObaleye, J. A.
dc.contributor.authorLawal, A.
dc.contributor.authorBabamale, H. F.
dc.contributor.authorAjibola, A. A.
dc.contributor.authorAdimula, V. O.
dc.contributor.authorLawal, M.
dc.date.accessioned2020-02-19T11:22:10Z
dc.date.available2020-02-19T11:22:10Z
dc.date.issued2017-05-04
dc.description.abstractIn this study, mixed Zn(II), Cu(II), Co(II) complexes of Isoniazid and vitamin C were synthesized and characterized by melting point, conductivity measurement, Fourier Transform Infra-red (FT-IR), Atomic Absorption Spectroscopy and elemental analyses. The bonding nature of the mixed parent ligands and the structure of the complexes were based on analytical and spectroscopic techniques. The complexes were proposed to have the formula [M1L1L2(Cl2)], [M2L1L2(SO4)], [M3L1L2(Cl2)] where M1 = Zn(II), M2 = Cu(II), M3= Co (II) L1= Isoniazid and L2 = Vitamin C. The infra-red data relate to the results of the most informative and indicative region. The result of spectra data confirmed that the two ligands were bidentate in their mode of coordination with the metal ions. The complexes are in octahedral geometry and the molar conductance was found to be non-electrolytic in nature. Antimicrobial test was carried out against four bacterial species namely Bacillus subtilus, Staphylococuss aureus, Escherichia coli and Pseudomonas aeroginosa. All the complexes showed higher antibacterial activity at the same concentration against the microorganisms used compared to the ligandsen_US
dc.identifier.urihttp://hdl.handle.net/123456789/3760
dc.language.isoenen_US
dc.publisherFaculty of Natural Sciences, Al- Hikmah University, Ilorin, Nigeriaen_US
dc.subjectCoordinationen_US
dc.subjectSpectraen_US
dc.subjectEvaluationen_US
dc.subjectBidentateen_US
dc.titleChelation, Characterization and Antimicrobial screening of Mixed Isoniazid - Vitamin C complexesen_US
dc.title.alternativeAl-Hikmah Journal of Pure and Applied Sciencesen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
AL- HIKMAH 2017- BAMIGBOYE ET AL.pdf
Size:
286.33 KB
Format:
Adobe Portable Document Format
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.69 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections