Synthesis, Characterization and Antimicrobial activities of some Mixed Ascorbic acid –Nicotinamide Metal Complexes

dc.contributor.authorLawal, A.
dc.contributor.authorAmolegbe, S. A.
dc.contributor.authorRajee, A. O.
dc.contributor.authorBabamale, H. F.
dc.contributor.authorYunus-Issa, M. T.
dc.date.accessioned2019-10-30T14:09:18Z
dc.date.available2019-10-30T14:09:18Z
dc.date.issued2015-01-25
dc.description.abstractThe present study aimed at synthesizing copper(II) and zinc(II) complexes of mixed ascorbic acid and nicotinamide and physiochemically characterize by solubility test, melting point, conductivity t e s t , i n f r a r e d , e l e c t r o n i c a n d p r o t o n n u c l e a r m a g n e t i c r e s o n a n c e t e c h n i q u e s . T h e r e s u l t o f t h e physiochemical studies indicated 1:1 stoichiometry and were supported by the spectroscopic data. T h e a n t i m i c r o b i a l a c t i v i t i e s o f t h e m i x e d c o m p l e x e s w e r e c a r r i e d o u t a g a i n s t B a c i l l u s s u b t i l i s , Escherichia coli, Staphylococcus aureus, Penicillum , spp Aspergillus flavus and Aspergillus niger. The result of the infrared data showed that ascorbi c acid coordinates through the oxygen of the carbonyl group and that of enolic C-2 hydroxyl grou p, while nicotinamide coordinates through the nitrogen atom of the pyridine ring. The result of t he antimicrobial studies showed that the mixed complexes have higher inhibitory activity than the original ligands against the tested bacteria and fu ngi speciesen_US
dc.identifier.urihttp://hdl.handle.net/123456789/3202
dc.language.isoenen_US
dc.publisherFaculty of Science, Bayero University Kano. Nigeriaen_US
dc.subjectAscorbic aciden_US
dc.subjectNicotinamideen_US
dc.subjectSynthesisen_US
dc.subjectAntimicrobialen_US
dc.subjectComplexesen_US
dc.titleSynthesis, Characterization and Antimicrobial activities of some Mixed Ascorbic acid –Nicotinamide Metal Complexesen_US
dc.title.alternativeBayero J. Pure and Applied Sciencesen_US
dc.typeArticleen_US

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