Chemical Composition and Antibacterial Activity of Fruit Essential Oil of Ocimum gratissimum (Linn). Grown in North Central Nigeria
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Date
2012
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Nigeria Journal of Pure and Applied Sciences
Abstract
Fresh pulverized fruits of Ocimum gratissimum (Linn) was hydrodistilled to afford 0.5% v/w oil. The oil was analysed by GC and GC-MS. The essential oil is characterized by high abundance of eugenol (53.7%) suspected to be principally responsible for the biological activity observed. Other principal constituent were 1,8-cineole (16.9%), β-ceryophylene (5.7%), allo-ocimene (5.5%), γ-muurolene (5.0%), γ-humulene (4.8%) and β-selinene (3.2%). The O. gratissimum fruit oil was active against most of the tested bacteria: Bacillus megaterium, Staphylococcus epidermidis, Escherichia coli with MIC of 25 mg mol-1
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Keywords
Ocimum gratissimum, Fruits, Antibacteria, GC-MS