Traumatic Brain Injury and Metabolic Dysfunction Among Head Injured Patients in a Tertiary Hospital in North-Central Nigeria.

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dc.contributor.authorOlayaki, L.A
dc.contributor.authorYusuf, A.S
dc.contributor.authorAdeleke, N.A,
dc.contributor.authorAbolude, N.A,
dc.contributor.authorOdetayo, F,
dc.contributor.authorBiliaminu, S.A.
dc.contributor.authorAfolabi, O.A.
dc.date.accessioned2020-01-30T10:23:29Z
dc.date.available2020-01-30T10:23:29Z
dc.date.issued2015
dc.descriptionTraumatic brain Injuryen_US
dc.description.abstractTraumatic Brain Injury (TBI) is a common health problem which is one of the main causes of chronic disability and it is associated with hormonal and metabolic disorders. This work was carried out to investigate the relationship between some stress hormones (i.e. prolactin and cortisol) and plasma glucose level in TBI patients. Twenty-five TBI patients were included in the study consecutively. All patients underwent basal hormonal and plasma glucose evaluation within 24 hours of admission. One of the patients died during the acute phase. The results of the study show that prolactin and glucose levels were positively correlated with the Glasgow Coma Scale (GSC). Cortisol levels were observed to be highest in the moderate TBI group with GSC score of 9-13. The results also showed that 80% (20 patients) of the patients were age 40 years and below and 84% (21 patients) were males. In conclusion, present data show that prolactin, cortisol and plasma glucose are disturbed in TBI. The disturbances in the levels of prolactin and glucose are related to the severity of TBI. However, there is no direct relationship between cortisol and severity of TBI. Our results also show that TBI is more common in males and young people.en_US
dc.description.sponsorshipOlayaki Luqman Aribidesi, Yusuf Ayodeji Salman, Adeleke Nurudeen Abiola, Abolude Nafisat Atinuke, Odetayo Fatai, Biliaminu Sikiru Abayomi and Afolabi Olushola Abdulrahmanen_US
dc.identifier.citationOlayaki L.A, Yusuf A.S, Adeleke N.A, Abolude N.A, Odetayo F, Biliaminu S.A. & Afolabi O.A. (2015): Traumatic Brain Injury and Metabolic Dysfunction Among Head Injured Patients in a Tertiary Hospital in North-Central Nigeria. Sierra Leone Journal of Biomedical Research 7(2): 15-19.en_US
dc.identifier.urihttp://hdl.handle.net/123456789/3582
dc.language.isoenen_US
dc.publisherPublished by the College of Medicine and Allied Health Sciences, University of Sierra Leoneen_US
dc.subjectTraumatic Brain Injury,en_US
dc.subjectPlasma Glucose,en_US
dc.subjectCortisol,en_US
dc.subjectProlactinen_US
dc.titleTraumatic Brain Injury and Metabolic Dysfunction Among Head Injured Patients in a Tertiary Hospital in North-Central Nigeria.en_US
dc.typeArticleen_US

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