Some Biochemical and Haematological Studies on the Prevalence of Congenital Malaria in Ilorin, Nigeria.
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Date
2007
Journal Title
Journal ISSN
Volume Title
Publisher
The Nigerian Society for Experimental Biology
Abstract
Abstract: A seven month study (March-September 2006) on the prevalence of congenital malaria was carried out at
the labour unit of three different hospitals within Ilorin metropolis: Eyitayo Hospital, Surulere Medical
Hospital and Children Specialist Hospital Centre Gboro Ilorin. A total of 130 blood samples were
collected from the mothers and their newborn babies and examined for malaria parasite using both thin
and thick films. Maternal packed cell volume (PCV) and genotype was also determined using haematocrit
method and cellulose acetate electrophoresis respectively. The prevalence rate of maternal, fetal, placental
and cord parasitaemia were 37(28.46%), 29(22.31%), 33(25.38%) and 30(23.08%) respectively. Malaria
infected maternal blood had a mild reduction in PCV level (p<0.05). Genotype showed strong correlation
with maternal, fetal, placental and cord parasitaemia (p<0.05). However, the effect of malaria prophylaxis
was shown to be more protective for the placental parasitaemia (p<0.05). Finally maternal age and parity
did not show strong correlation with Maternal, fetal, placental and cord parasitaemia (p>0.05).
Description
Keywords
Malaria, Mothers, Newborns
Citation
Kolawole, O.M, Jimoh A.G, Babatunde A.S, Balogun O.R & Kanu I.G. (2007). Some Biochemical and Haematological Studies on the Prevalence of Congenital Malaria in Ilorin, Nigeria. Biokemistri. 19 (2); 59-64.