Prevalence of Dyslipidemia, Drug Therapy Problems, and Medication Adherence in Type 2 Diabetes Mellitus Patients in North Central Nigeria
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Date
2024-02-16
Journal Title
Journal ISSN
Volume Title
Publisher
Libyan International Medical University, Libya.
Abstract
Abstract Background Patients with diabetes mellitus have an increased risk of developing
dyslipidemia, predisposing them to macro- and microvascular consequences such as
coronary heart disease.
Aim The aim of this study was to assess the prevalence of dyslipidemia, drug therapy
problems (DTPs), and medication adherence in type 2 diabetes mellitus (T2DM)
patients in a tertiary hospital in North Central Nigeria.
Method This study was a cross-sectional convenient sampling of eligible patients
conducted in the General Outpatient Department of General Hospital, Ilorin, from
March to May 2022. A validated questionnaire was administered to obtain all relevant
information on sociodemographic information, and blood samples were collected in a
medium plain heparinized tube and sent to the laboratory where fasting blood sugar,
high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol
(LDL-C) values were calculated as appropriate. Morisky’s Medication Adherence Scale 8
(MMAS-8) was used to capture patient’s adherence level, and DTP was assessed using
the Pharmaceutical Care Network Europe (PCNE) Criteria version 7. Ethical approval
was obtained from the Ministry of Health, Ilorin. Statistical Package for Social Sciences
was used to analyze the data collected for descriptive and inferential statistics.
Results The mean age of the respondents was 60 0.7 years. Of the 60 respondents, 25
(41.67%) were males and 35 (58.33%) were females. All the respondents had dyslipidemia,
30% respondents were identified with a DTP of nonadherence, 16.7% needed additional
drug/monitoring, dosage was too low in 11.7%, and 11.6% could not afford their medications
due to high cost. In all, 45 (75%) respondents had poor sugar control and 33 (55%) had poor
blood pressure control. Using MMAS-8, the majority (41, [68.30%]) of the respondents were
found to have poor adherence to their diabetic medications.
Conclusion High prevalence of dyslipidemia, poor medication adherence, and DTPs
were found in the T2DM patients in this study
Description
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Keywords
dyslipidemia, type 2 diabetes mellitus, medication adherence, drug therapy problem, Framingham risk score
Citation
Aliyu, F.O. Orimogunje, T., Bello, S. I., Abdulbaki, M, Jamiu, M. O. & Ogaji, I. J. (2024): Prevalence of Dyslipidemia, Drug Therapy Problems, and Medication Adherence in Type 2 Diabetes Mellitus Patients in North Central Nigeria. Libyan International Medical University Journal. Published by Libyan International Medical University, Libya