Antibaterial activity of the GC-MS characterized essential oil from the leaves of Crassocephalum crepidiodes from North Central Nigeria

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dc.contributor.authorRidwan Olanrewaju Ismaeel
dc.contributor.authorSaliu Bolanle Kudirat
dc.contributor.authorLamidi Ajao Usman
dc.contributor.authorFatihat Hassan
dc.contributor.authorOyeleye Medinat Adedeji
dc.contributor.authorEtimbuk Daniel Akpan
dc.contributor.authorSambo Ameen Olanrewaju Fadhilat
dc.date.accessioned2025-04-29T10:36:37Z
dc.date.available2025-04-29T10:36:37Z
dc.date.issued2025-02-21
dc.description.abstractThis study was carried out to isolate and evaluate the antibacterial activity of the leaf essential oil of Crassocephalum crepidiodes against selected bacteria. Hydrodistillation of 500 g of sample of the plant’s leaves (for four hours) gave a yield of 0.10 %(w/w) of volatile oil. The oil was characterized using GC-MS and the result showed abundant of monoterpenoids in the oil and D-limonene (77.1 %) was the predominant constituent. Meanwhile, linalool (2.6 %), α-pinene (5.5 %), β-caryophyllene (2.4 %), and α-terpineol (2.6 %) were minor relative to the amount of limonene but are significant constituents of the oil. The agar well diffusion method was used to determine the antibacterial activity of the oil against Enterococcus faecalis, Bacillus cereus, Staphylococcus aureus, Streptococcus pneumoniae, Salmonella typhi and Salmonella sp. Gram-positive bacteria were more susceptible to the oil than Gram-negative bacteria. S. aureus was the most susceptible to inhibition at the lowest concentration (25 %) used in this study. Therefore, the oil has applications for the treatment of infections caused by the Gram-positive bacteria, especially S. aureus.
dc.identifier.citationCrassocephalum, crepidiodes, Staphylococcus, aureus, D- limonene
dc.identifier.issn2958-9630
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/123456789/15680
dc.language.isoen
dc.publisherJournal of Essential Oil & Plant Composition
dc.relation.ispartofseries3(1); 19-25
dc.titleAntibaterial activity of the GC-MS characterized essential oil from the leaves of Crassocephalum crepidiodes from North Central Nigeria
dc.typeArticle

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