Serum brain natriuretic peptide in healthy Nigerian newborn babies

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dc.contributor.authorIssa, A
dc.contributor.authorAbdulkadir, Mohammed Baba
dc.contributor.authorAdesiyun, O.O.
dc.contributor.authorOwolabi, B
dc.contributor.authorBello, S.O.
dc.contributor.authorBakare, R.R.
dc.date.accessioned2023-01-09T12:56:17Z
dc.date.available2023-01-09T12:56:17Z
dc.date.issued2021
dc.description.abstractBackground: Brain natriuretic peptide (BNP) is a sensitive biomarker that is valuable in the management of childhood heart failure. Studies have reported racial differences in the level of BNP, especially in the adult population. The level of BNP in healthy Nigerian newborn babies is unknown. Hence, we determined the level of BNP in healthy term appropriate for gestational age (AGA) newborn babies. Methods: This was a cross- sectional study,85 healthy term AGA newborn babies aged 24 to 72 hours. The babies had relevant demographic parameters docu mented in a proforma and BNP assay analysed using ELISA method. Results: The median IQR serum BNP level was 341.43 (313.39 to 425.45) pg/ml. The median level in females, was higher than males, {393.86 (296.97- 460.62) pg/ml vs328.05 (313.61-389.39) pg/ml, p >0.05}.There was no significant relationship between serum BNP and birth weight, chronological age, gestational age, or mode of delivery (p>0.05 in each case). Conclusion: The study demonstrated high BNP levels in healthy term Nigerian newborns. There was no relationship between BNP, the chronological age, birth weight, gender, gestational age or mode of delivery in babies between 24 to 72 hours of lifeen_US
dc.identifier.citation11. Issa, A., Abdulkadir, M. B., Adesiyun, O. O., Owolabi, B., Bello, S. O., & Bakare, R. R. (2021). Serum brain natriuretic peptide in healthy Nigerian newborn babies. Nigerian Journal of Paediatrics, 48(1), 8-11en_US
dc.identifier.urihttps://uilspace.unilorin.edu.ng/handle/20.500.12484/8280
dc.language.isoenen_US
dc.publisherPaediatric Association of Nigeriaen_US
dc.subjectBrain natriuretic peptide, term babies, healthy, Nigeriaen_US
dc.titleSerum brain natriuretic peptide in healthy Nigerian newborn babiesen_US
dc.typeArticleen_US

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