Association between Blood Pressure Dipping Patterns and Left Ventricular Hypertrophy among Apparently Healthy Normotensive Nigerians.
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Date
2021
Journal Title
Journal ISSN
Volume Title
Publisher
College of Health Sciences, Ekiti state University, Ado-Ekiti.
Abstract
ackground
Abnormal blood pressure dipping pattern has been associated left ventricular hypertrophy among Africans with systemic
hypertension. However, more studies are required to show whether abnormal blood pressure (BP) dipping patterns are
associated with left ventricular hypertrophy (LVH) in healthy normotensive patients. This study determined the
association between BP dipping patterns and left ventricular hypertrophy among normotensive Nigerians.
Methods
This was a cross-sectional study in which 120 normotensive individuals with no co-morbidities had ambulatory blood
pressure monitoring (ABPM) and echocardiography. We defined extreme dippers, normal dippers, non-dippers and
reverse dippers as nocturnal systolic BP decline of (≥ 20%), (10% to 19%), (0 to 9%) and (<0%) respectively.
Results
Fifty-four (45%) were males, the mean age and body mass index were 37.0 ± 10.1years and 24.0 ±4.2 kg/m2 respectively.
Sixty-nine (57.5%) were non-dippers and 71 (59.2%) had LVH. Reverse dippers had the highest left ventricular mass
index, it was not statistically significant. Binary logistic regression showed age as the only predictor of left ventricular
hypertrophy (OR=1.055, 95% CI=1.004-1.109; p-value = 0.033).
Conclusions
A high prevalence of non-dipping pattern and left ventricular hypertrophy was found among apparently healthy Nigerian
normotensives. Increasing age was the only predictor of LVH in our study population. Hence, ABPM and
echocardiography are recommended to accurately assess cardiovascular risk in apparently healthy Nigerian
normotensives.
Description
Keywords
Dipping patterns, healthy, normotensive, echocardiography, left ventricular hypertrophy, Nigeria.
Citation
The Nigerian Stethoscope 3(1):26-30.