Isovitexin from Kigelia pinnata, A Potential Eco-friendly Nematicidal Agent.
No Thumbnail Available
Date
2014
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Tropical Agriculture. University of West Indies, Trinidad
Abstract
Synthetic pesticides are usually environmentally hazardous. In an attempt to obtain an eco-friendly alternative to
synthetic nematicidal agents, isovitexin, a flavonoid glycoside isolated from butanol fraction of the leaf extract of
Kigelia pinnata was examined for its in vitro nematicidal potential. The chemical structure of the isovitexin was
confirmed by comparing its UV, IR, MS and NMR spectroscopic data with that reported in literature. The
compound induced a hundred percent mortality at 24 h of exposure and inhibited egg hatch of Meloidogyne
incognita at a concentration of 0.16 mg/mL. There was no significant difference (p<0.05) in the action of isovitexin
and the synthetic nematicide, oxamyl, when tested at the same concentration. The bioactivity and toxicity
evaluation on ‘molinspiration’ and ‘toxpredict’ evaluators indicated that isovitexin is a potentially bioactive
compound with low genotoxic carcinogenicity and high enzyme inhibition activity. The biodegradability evaluation indicated that it belongs to a class 2 persistent chemical. The results of this study could be harnessed to make isovitexin commercially available as a natural nematicide. This is the first account of isovitexin being
isolated from Kigelia pinnata and evaluated for nematicidal potential.
Description
Nematode Control
Keywords
Kigelia pinnata; Meloidogyne incognita; flavonoid glycoside; nematicide; genotoxic; carcinogenicity.
Citation
Atolani, O., Fabiyi, O. A. and Olatunji, G.A. (2014). Isovitexin from Kigelia pinnata, A Potential Eco-friendly Nematicidal Agent. Tropical Agriculture. Volume 91 (2): 67-74.