Serum urea and creatinine levels in pregnant women attending Antenatal clinic in General Hospital Suleja- Niger state

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2015

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Faculty of Physical Sciences, University of Ilorin

Abstract

Levels of renal function parameters (urea and creatinine) were assessed in normal pregnant women attending General Hospital Suleja- Niger State in order to identify the association between these biochemical parameter and gestation period (first, second and third trimester) compared to those of normal non- pregnant women as a control. A total of 200 women were participating in the study, they include 150 pregnant women and 50 nonpregnant women. The result obtained showed a significant (p<0.05) lower value in mean serum urea level in the pregnant group during the 3rd trimester of the pregnancy, while the mean value of urea shows a non-significant (p<0.05) decrease throughout the 1st and 2nd trimester of the pregnancy when compared with the control group. There was a significant difference in serum creatinine between the 1st and 3rd trimester, which were higher in the 3rd trimester than in the 1st and 2nd tirmester of the pregnancy, but no significant difference in serum creatinine between 1st and 2nd trimester of the pregnancy when compared with the control group. All these changes could be due to physiological adaptations of the mother to the growing fetus. Keywords: Serum creatinine, urea, pregnant women, General Hospital, Suleja.

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