Synthesis, Characterization and Biological Studies of Mixed Paracetamol - Ascorbic acid Metal Complexes

Simple item page
dc.contributor.authorBabamale, H. F.
dc.contributor.authorLawal, A.
dc.contributor.authorOloyede, E. A.
dc.contributor.authorRajee, O. A.
dc.date.accessioned2020-02-19T10:42:10Z
dc.date.available2020-02-19T10:42:10Z
dc.date.issued2016-09-25
dc.description.abstractMixed ligand-metal complexes of Paracetamol and Ascorbic acid were synthesized using FeCl2.4H2O, CuCl2.2H2O, NiCl2.6H2O, CoCl2.6H2O and ZnSO4 salts based on two concentrations (3mmol and 5mmol). The complexes were characterized using some physical techniques such as melting point, solubility, conductivity measurement and spectroscopic analyses such as UV-Visible spectroscopy, Atomic absorption spectroscopy, and Infrared spectroscopy. Based on the physical and spectroscopic results, the coordination of the metal was through the phenolic oxygen and carbonyl oxygen in paracetamol while it was through the carbonyl oxygen and C-2 hydroxyl group in ascorbic acid. The complexes were also screened for their antimicrobial activities against some isolates of Enterococcus faecalis, Staphylococcus aureus, Clostridium difficile, Klebsiella sp., Helicobacter pylorien_US
dc.identifier.issn1119-8362
dc.identifier.urihttp://hdl.handle.net/123456789/3742
dc.language.isoenen_US
dc.publisherWorld Bank Assisted National Agriculture Research Projects (NAARP), Faculty of Science, University of Port-Harcourt, Nigeriaen_US
dc.subjectMetalen_US
dc.subjectMixed ligand-metal complexesen_US
dc.subjectParacetamolen_US
dc.subjectAscorbic aciden_US
dc.subjectIsolatesen_US
dc.titleSynthesis, Characterization and Biological Studies of Mixed Paracetamol - Ascorbic acid Metal Complexesen_US
dc.title.alternativeJournal of Applied Science and Environmental Managementen_US
dc.typeArticleen_US

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
JASEM 2016- BABAMALE ET AL.pdf
Size:
182.67 KB
Format:
Adobe Portable Document Format
Description:
Main article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.69 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections