Interplay between Lipid Profile and Weight-Related Outcomes in Healthy Overweight Adults: In-sights from Comprehensive Analyses

No Thumbnail Available



Journal Title

Journal ISSN

Volume Title


Faculty of Basic Medical and Clinical Sciences, Ladoke Akintola University of Technology


Background: The escalating prevalence of overweight and obesity has heightened concerns about cardiovascu-lar health. The intricate interplay between lipid profile variables and weight-related outcomes plays a pivotal role in shaping cardiovascular risks among individuals with excess body weight. This study investigates the associa-tions between lipid profile variables and weight-related indicators in a cohort of healthy, overweight adults, shedding light on potential implications for cardiovascular risk management. Methods: The prevalence of metabolic syndrome, risk factors, and related lifestyle in adult Myanmar citizens were examined in the Inter-University Consortium for Political and Social Research Study (ICPSR146521) using prospective data. The patient's lipid profiles and demographic data were statistically analyzed using the statistical MedCalc tool. Statistical significance was determined using a 0.05 p-value. Results: Results demonstrate that while BMI is influenced by multiple factors beyond lipid profile variables, waist circumference exhibits moderate association with these variables. Notably, triglycerides significantly cor-related with waist circumference, suggesting a potential role in visceral fat accumulation. Additionally, the study highlights the impact of high-density lipoprotein (HDL) cholesterol levels on body weight, indicating that higher HDL levels are associated with lower body weights among healthy overweight adults. Conclusion: This study provides comprehensive insights into the complex relationship between lipid profile variables and weight-related outcomes among healthy, overweight adults. These findings underscore the im-portance of weight management strategies for cardiovascular health and suggest potential avenues for targeted interventions. By understanding the interplay between lipid profiles and obesity, clinicians and public health professionals can develop more effective strategies to mitigate cardiovascular risks in this demographic.



BMI, HDL, LDL, overweight, dyslipidemia, waist circumference