Antibacterial Activities of Some Antidiarrheal Herbal Concoctions Locally Prepared in Ilorin, Nigeria, on Fecal Isolates
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Date
2015
Journal Title
Journal ISSN
Volume Title
Publisher
Centrepoint
Abstract
Antibacterial activity of herbal concoctions commonly used to treat diarrhea
in Ilorin, Nigeria was determined against fecal isolates. Aqueous extracts of
different combinations of the herbs used were prepared by soaking for
eighteen days. Samples were taken daily for four days and weekly thereafter
and used to challenge bacteria isolated from human feces. The efficacy of
the herbal extracts was compared with a standard antibiotic, streptomycin.
Most of the isolates were inhibited by the 48 hours herbal extracts.
Inhibition zone ranged from 11.4 to 20.0 mm and 4.6 to 19.8 mm for the
adult men and women extracts; and 9.6 to 32.0 mm for the children extract.
The minimum inhibitory concentration ranged from 25 to 100%. Apart from
Enterococcus feacalis and Staphylococcus aureus, susceptibility to the
herbal extracts compared favorably with reference drug, streptomycin with
percentage inhibition reaching 100, 120, 150 and 160 respectively for
Proteus vulgaris, Salmonella enteritica, Escherichia coli, and Klebsiella sp.
Aqueous extract of a combination of herbs used for treatment of diarrhea in
Ilorin has antibacterial activity comparable with streptomycin and can
therefore be recommended for use after determining its toxicity.
Description
Keywords
Antibacterial, herbal concoctions, fecal isolates, diarrhea
Citation
Saliu et al., 2015